- Laser Material Processing Techniques
- Additive Manufacturing Materials and Processes
- Advanced Surface Polishing Techniques
- Solid State Laser Technologies
- Cancer-related molecular mechanisms research
- Welding Techniques and Residual Stresses
- Laser-induced spectroscopy and plasma
- Kidney Stones and Urolithiasis Treatments
- High Entropy Alloys Studies
- Pediatric Urology and Nephrology Studies
- Laser Design and Applications
- Additive Manufacturing and 3D Printing Technologies
- Tribology and Wear Analysis
- Parkinson's Disease Mechanisms and Treatments
- Nanocluster Synthesis and Applications
- Ureteral procedures and complications
- Advanced machining processes and optimization
- Tunneling and Rock Mechanics
- Seismic Waves and Analysis
- Advanced Sensor and Energy Harvesting Materials
- Polymer Nanocomposites and Properties
- Reproductive Biology and Fertility
- Circular RNAs in diseases
- Ovarian function and disorders
- Neurological disorders and treatments
Dalian Maritime University
2025
First Affiliated Hospital of Harbin Medical University
2019-2024
Zhongyuan University of Technology
2020-2024
Xuchang University
2024
China Academy of Engineering Physics
2022-2024
Harbin Medical University
2013-2024
Lanzhou University
2024
Lanzhou University Second Hospital
2024
Hefei First People's Hospital
2023
Anhui Medical University
2023
Abstract This paper tried to explore ANRIL expression in ovarian cancer and how it affects cisplatin-sensitivity of cells via regulation let-7a/high-mobility group protein A2 (HMGA2) axis. qRT-PCR was used detect let-7a levels tissues cell lines (SKOV3 SKOV3/DDP). Then were randomly assigned into Blank, negative control siRNA, inhibitor, siRNA+let-7a-inhibitor groups. CCK-8 assay applied for assessing viability treated with different concentrations cisplatin. Flow cytometry employed test...
Preventing the thermal damage of diamond abrasives is major challenge composites in field super-hard tools by laser additive manufacturing. In presented work, we established a quantitative framework to accurately evaluate behaviour and relevant microstructure-performance characteristics, using CuSn10-diamond composite powder bed fusion-laser beam (PBF-LB). By simulating history molten pool microstructure characterisation, critical temperature 1491.6°C graphitisation was obtained. Below...
ABSTRACT Patches can help fix security vulnerabilities and optimize software performance, thereby enhancing the quality of software. Unfortunately, patches generated by automated program repair tools are not always correct, as they may introduce new bugs or fail to fully rectify original issue. Various methods for evaluating patch correctness have been proposed. However, most face challenge capturing long‐distance dependencies in evaluation, which leads a decline predictive performance...
Importance Global developmental delay (GDD) is characterized by a complex etiology, diverse phenotypes, and high individual heterogeneity, presenting challenges for early clinical etiologic diagnosis. Cognitive impairment the core symptom, despite pivotal role of genetic factors in GDD development, understanding them remains limited. Objectives To assess utility detection patients with to examine potential molecular pathogenesis identify targets intervention. Design, Setting, Participants...
A nanosecond-millisecond combined pulse laser (CPL) drilling method was proposed for alumina ceramic. The total energy consumption of the CPL 1/7 that a conventional millisecond laser, and quality better. simulation results demonstrated that, due to nonuniform reflection in keyhole, ellipse keyhole ablated by off-axis incident nanosecond pulses had no effect on circularity through hole. In addition, multireflection enhanced absorption, so could be used as target limiting absorption...
A novel combined laser pulses (CLPs) consisting of a millisecond (ms) pulse and an assisted nanosecond (ns) train was proposed for drilling alumina ceramic. The processing efficiency quality were well improved by spatially temporally superposing the ms ns beams. As result, due to multi-reflection keyhole ejection melt, superposed CLPs could decrease energy consumption order magnitude compared with conventional pulse. On other hand, spatial distribution on focal plane elliptical off-axis...
Aluminum is a kind of metal that we often encounter. It can also be absorbed by the human body invisibly and will affect our bodies to certain extent, e.g., causing symptoms associated with Alzheimer's disease. Therefore, detection aluminum particularly important. The methods detect ions include precipitation electrochemical methods, which are cumbersome costly. Fluorescence fast sensitive method low cost non-toxicity. Traditional fluorescent nanomaterials have high cost, toxicity, cause...
Abstract The total heat input by the laser directly affects temperature distribution of rotor shaft during cladding process, and then its coaxiality. This article uses ANSYS for numerical simulation to study effect on deformation process. Simulate analyze stress fields inside using thermal coupling. results show that changing pitch, axial width irradiation duration change induced input, a more uniform can be generated in shaft. increase uniformity reduce cladding. Using equipment, iron based...
Background . PD patients present high incidence of pain with unknown pathogenesis. Objective We investigated the relation COMT polymorphisms rs4633 and rs6267 pain. Subjects Methods One hundred 105 controls were evaluated simplified Mc GILL scale VAS scale. assessed H&Y grade, UPDRS score, HAMD Polymorphisms detected by PCR direct sequencing. Results Fifty-seven percent experienced pain, consisting PD-related (64.91%) (the majority was dystonia pain) non-PD-related (35.09%) (psychogenic...
Polycystic ovary syndrome (PCOS) is an endocrine disease that increases the risk of infertility. Circular RNAs (circRNAs) play important roles in regulating biological processes PCOS. Our study was designed to explore function circ-FURIN PCOS.Circ-FURIN expression detected using RT-qPCR. The protein AVEN, BCL2, XIAP and AREL1 measured western blot. Dual-luciferase reporter RNA pull-down assays were applied clarify interaction between miR-195-5p or BCL2. Functionally, cell proliferation...
Although superhydrophobic surfaces have various promising applications, their fabrication methods are often limited to 2D plane that vulnerable abrasion and adhesion the substrate. Herein, an ultraviolet (UV) curable ink with bulk superhydrophobicity, consisting of poly(dimethylsiloxane) (PDMS) resins, hydrophobic silica, solvent (porogen), was successfully developed for UV-assisted direct write printing processing. After UV curing followed by evaporation, generated porous structure...
This paper proposes a novel construction of efficient certificateless aggregate signature (CLAS) scheme.On basis the computational Diffie-Hellman (CDH) assumption, proposed scheme can be proven existentially unforgeable against adaptive chosen-message attacks.The new also requires small constant pairing computations for verification, which is independent number signers.Most importantly, certain synchronization aggregating randomness avoided by scheme.All signers don't need to share same...