A5009297379- earthquake and tectonic studies
- Seismology and Earthquake Studies
- Geological and Geochemical Analysis
- Seismic Waves and Analysis
- High-pressure geophysics and materials
- Earthquake Detection and Analysis
- Cellular transport and secretion
- Seismic Imaging and Inversion Techniques
- Microtubule and mitosis dynamics
- Methane Hydrates and Related Phenomena
- Cellular Mechanics and Interactions
- Geological and Geophysical Studies
- Geophysics and Sensor Technology
- Protist diversity and phylogeny
- Lipid Membrane Structure and Behavior
- Renal Diseases and Glomerulopathies
- Erythrocyte Function and Pathophysiology
- Seismic Performance and Analysis
- Genetic Neurodegenerative Diseases
- Landslides and related hazards
- Geological formations and processes
- Wnt/β-catenin signaling in development and cancer
- Geotechnical and Geomechanical Engineering
- Photosynthetic Processes and Mechanisms
- Geological Modeling and Analysis
Okayama University
2015-2024
National Research Institute for Earth Science and Disaster Resilience
2015-2024
Sumitomo Mitsui Banking Corporation
2024
Ministry of Education, Culture, Sports, Science and Technology
2017-2018
Isuzu Advanced Engineering Center (Japan)
2017
Japan Science and Technology Agency
2015-2016
The University of Tokyo
2001-2014
Takeda (Japan)
2014
University of Cambridge
2008-2013
Cancer Research UK
2008-2012
Volcanic eruptions are caused by the release of pressure that has accumulated due to hot volcanic fluids at depth. Here, we show extent regions affected pressurized can be imaged through measurement their response transient stress perturbations. We used records seismic noise from Japanese Hi-net network measure crustal velocity changes below 2011 moment magnitude (M(w)) 9.0 Tohoku-Oki earthquake. interpret coseismic reductions as related mechanical weakening crust dynamic associated with...
Abstract Noise‐based crustal seismic velocity changes are known to be affected by environmental perturbations, such as rainfall, atmospheric pressure loading, and temperature changes. Similar geodetic observations, these external perturbations can mask the effects of tectonic volcanic processes. In this study, we benefit from dense Hi‐net short‐period network that covers entire Japan measure continuous in velocities over a few years, using noise‐based monitoring. Some strong seasonal...
Summary Cytokinesis controls the proper segregation of nuclear and cytoplasmic materials at end cell division. The chromosomal passenger complex (CPC) has been proposed to monitor final separation two daughter cells cytokinesis in order prevent abscission presence DNA cleavage site, but precise molecular basis for this is unclear. Recent studies indicate that could be mediated by assembly filaments comprising components endosomal sorting required transport-III (ESCRT-III). Here, we show CPC...
Anillin, one of the first factors recruited to cleavage site during cytokinesis, interacts with actin, myosin II and septins, is essential for proper organization actomyosin contractile ring. We employed affinity-purification methodology coupled mass spectrometry identify Anillin-interacting molecules in Drosophila cells. isolated several actin proteins, three five septins RacGAP50C (Tum), a component centralspindlin complex. Using drug RNA interference (RNAi) treatments we established that...
Abstract After the occurrence of 2011 magnitude 9 Tohoku earthquake, seismicity in overriding plate changed. The appears to form distinct belts. From spatiotemporal distribution hypocenters, we can quantify evolution after earthquake. In some earthquake swarms near Sendai (Nagamachi‐Rifu fault), Moriyoshi‐zan volcano, Senya fault, and Yamagata–Fukushima border (Aizu‐Kitakata area, west Azuma volcano), observe temporal expansion focal area. This is attributed fluid diffusion. Observed...
Formins are conserved actin nucleators which promote the assembly of filaments for formation diverse structures. In fission yeast Schizosaccharomyces pombe, formin cdc12p is required specifically in actin-based contractile ring during cytokinesis. Here, using a mutational analysis cdc12p, we identify regions responsible and localization. Profilin-binding residues FH1 domain regulate processive barbed-end capping by FH2 domain. Studies photobleaching (FRAP) sensitivity to latrunculin A...
The endocytic protein dynamin participates in the formation of actin-based membrane protrusions such as podosomes, pseudopodia, and invadopodia, which facilitate cancer cell migration, invasion, metastasis. However, role at leading edge cells is unclear. In this study, we demonstrate that ubiquitously expressed 2 isoform facilitates migration by stabilizing F-actin bundles filopodia lung line H1299. Pharmacological inhibition decreased filopodial formation. Furthermore, cortactin mostly...
Dynamin is a mechanochemical GTPase essential for membrane fission during clathrin-mediated endocytosis. forms helical complexes at the neck of clathrin-coated pits and their structural changes coupled with GTP hydrolysis drive fission. its binding protein amphiphysin cooperatively regulate remodeling fission, but precise mechanism remains elusive. In this study, we analyzed dynamin-amphiphysin using electron microscopy (EM) high-speed atomic force (HS-AFM). Interestingly, HS-AFM analyses...
Membrane remodeling is required for dynamic cellular processes such as cell division, polarization, and motility. BAR domain proteins dynamins are key molecules in membrane that work together deformation fission. In striated muscles, sarcolemmal invaginations termed T-tubules excitation–contraction coupling. BIN1 DNM2, which encode a protein dynamin 2, respectively, have been reported to be causative genes of centronuclear myopathy (CNM), hereditary degenerative disease skeletal muscle,...
A recent extensive seismic wide‐angle experiment revealed a new image of crustal and uppermantle structure across Northern Honshu Arc, Japan. The western part the arc recorded deformation by Miocene back spreading Sea crust is composed highly deformed Tertiary sedimentary layers, relatively low velocity (5.75–5.9 km/s) crystalline basement 15‐km thick lower with 6.6–7.0 km/s. Clear westward thinning from 32 to 27 km represents extensional backarc spreading. attains maximum thickness...
Determining the structure of subduction zones is important for understanding mechanisms generation interplate phenomena such as megathrust earthquakes. The peeling off uppermost part a subducting slab and accretion to bottom an overlying plate (underplating) at deep regions has been inferred from exhumed metamorphic rocks seismic imaging, but direct evidence this process lacking. By comparing reflection profiles with microearthquake distributions in central Japan, we show that repeating...
Cytokinesis is a highly ordered cellular process driven by interactions between central spindle microtubules and the actomyosin contractile ring linked to dynamic remodelling of plasma membrane. The mechanisms responsible for reorganizing membrane at cell equator its coupling in cytokinesis are poorly understood. We report here that Syndapin, protein containing an F-BAR domain required curvature, contributes around cytokinesis. Syndapin colocalizes with phosphatidylinositol 4,5-bisphosphate...
Intense swarm‐like seismicity associated with shallow normal faulting was induced in Ibaraki and Fukushima prefectures, Japan, following the 2011 Tohoku‐Oki earthquake. This shows a systematic spatiotemporal evolution, but little is known of heterogeneity crustal structure this region, or its influence on evolution seismicity. Here, we elucidate high‐resolution model region determine precise hypocenter locations. Hypocenters Prefecture reveal planar earthquake alignment dipping SW at ~45°,...
[1] Focal mechanisms have been determined from P wave polarity data as well body amplitudes for 154 microearthquakes that occurred around the Atotsugawa fault in central Japan between 2002 and 2004. While we found many with a pure strike-slip mechanism is similar to faulting style of fault, considerable number reverse components are also occurring. Most axes horizontal oriented WNW-ESE direction, which conforms general tectonic trend this area. In contrast, T wide range plunge, suggesting...
We have generated a high-resolution catalog called the "Japan Unified hIgh-resolution relocated Catalog for Earthquakes" (JUICE), which can be used to evaluate geometry and seismogenic depth of active faults in Japan. > 1.1 million hypocenters from NIED Hi-net events occurred between January 2001 December 2012, 40 km. apply relative hypocenter determination method data each grid square, entire Japan is divided into 1257 squares parallelize relocation procedure. double-difference method,...
The northern Fossa Magna (NFM) is a back-arc rift basin filled with thick Tertiary sediments, which show strong NW-SE shortening deformation. In the NFM, there exist two major active fault systems, Itoigawa-Shizuoka Tectonic Line system (ISTL) and Western Nagano Basin (WNB), both of have great potentials to cause destructive earthquakes. By reanalyzing five sets refraction/wide-angle reflection data, we successfully obtained detailed consistent models crustal structure in NFM region. It was...
To understand the mechanism of an intensive non-volcanic seismic swarm in Kii Peninsula, Japan, we used a dense linear array to measure fine-scale variations velocities and converted teleseismic waves. A low-velocity anomaly confined just beneath area is clearly imaged, which correlates spatially with uplifted surface highly conductive strong attenuative body. These results suggest that fluids such as partial melt or water are present this area. It notable island arc Moho below at depth...