A5102861043- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Global Cancer Incidence and Screening
- Ovarian cancer diagnosis and treatment
- Advances in Oncology and Radiotherapy
- Global Health and Surgery
- Uterine Myomas and Treatments
- Intraperitoneal and Appendiceal Malignancies
- Economic and Financial Impacts of Cancer
- Cancer Risks and Factors
- BRCA gene mutations in cancer
- Colorectal and Anal Carcinomas
- Palliative Care and End-of-Life Issues
- Primary Care and Health Outcomes
- Pelvic and Acetabular Injuries
- Genetic factors in colorectal cancer
- Global Health Workforce Issues
- Renal cell carcinoma treatment
- Cancer-related molecular mechanisms research
- Congenital Diaphragmatic Hernia Studies
- Sarcoma Diagnosis and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Genital Health and Disease
- Cardiomyopathy and Myosin Studies
- Clinical practice guidelines implementation
Massachusetts General Hospital
2015-2024
Harvard University
2015-2024
Mbarara University of Science and Technology
2023-2024
Newcastle University
2024
Boston University
2023-2024
King's College London
2023
British Heart Foundation
2023
Mbarara National Referral Hospital
2023
Harvard Global Health Institute
2022
Partners In Health
2018
Objective: To determine the efficacy of conservative management atypical hyperplasia and well-differentiated carcinoma endometrium in women under age 40. Methods: Pathology records were searched to identify 40 diagnosed with or between January 1990 1996. All available biopsy, curettage, hysterectomy specimens reviewed. Follow-up was obtained from patients' gynecologists. Results: Sixty-seven identified. Atypical found 32 patients 35 patients. Seven excluded analysis; four declined all...
Purpose Cervical cancer is the leading cause of death among 20 million women with HIV worldwide. We sought to determine whether infection affected survival in invasive cervical cancer. Patients and Methods enrolled sequential patients Botswana from 2010 2015. Standard treatment included external beam radiation brachytherapy concurrent cisplatin chemotherapy. The effect on was estimated by using an inverse probability weighted marginal Cox model. Results A total 348 were enrolled, including...
Purpose The decision about prophylactic oophorectomy is difficult for many premenopausal women with BRCA1/2 mutations because of concerns and controversy the use hormone replacement therapy (HRT) after oophorectomy. Patients Methods A Markov analytic model used most current epidemiologic data to assess expected outcomes or without HRT (to age 50 years life) in cohorts mutations. Sensitivity analyses were conducted impact alternative assumptions effects HRT, oophorectomy, risks cancer...
To address gaps in access to cervical cancer screening and early diagnosis of breast services Sub-Saharan African (SSA), this scoping review was conducted explore facilitators barriers that exist on the patient-, provider-, system-level. An extensive literature search accordance with methodology Cochrane guidelines. Our criteria were limited original research studies community or clinical settings SSA within last 10 years (2010-2020). Themes found from included patient knowledge provider...
Abstract Addressing the global disparity in cancer care necessitates development of rapid and affordable nucleic acid (NA) testing technologies. This need is particularly critical for cervical cancer, where molecular detection human papillomavirus (HPV) has emerged as an accurate screening method. However, implementing this transition low- middle-income countries been challenging due to high costs centralized facilities required current NA tests. Here, we present CreDiT (CRISPR Enhanced...
To investigate disparities in treatment and outcomes between African-American white women with endometrial cancer.
Purpose Chemotherapy for ovarian cancer is usually administered by medical oncologists (MOs) or gynecologic (GOs). GOs perform a broad spectrum of surgical and activities while managing limited number diseases; MOs specialize in the administration chemotherapy but manage array diseases. We asked whether survival, treatment, toxicity differed according to type specialist providing after surgery. Patients Methods Using Surveillance, Epidemiology, End Results (SEER) -Medicare data patients ≥ 65...
Vaginal cuff dehiscence with small bowel evisceration after hysterectomy is a rare event that may be occurring more frequently the advent of robotic laparoscopic hysterectomies.Two women underwent total for menorrhagia and stage I endocervical adenocarcinoma, respectively. Each presented 7-8 weeks postoperatively abdominal pain vaginal pressure intercourse. The protruded into vagina through dehisced cuff. Both cuffs were repaired vaginally delayed absorbable suture. One repair required...
Journal Article Persistence of Cell-Mediated and Humoral Immune Responses in Healthy Children Immunized with Live Attenuated Varicella Vaccine Get access Barbara Watson, Watson Division Allergy, Immunology, Infectious Diseases, Joseph Stokes Jr. Research Institute, Children's Hospital Philadelphia, Pennsylvania Reprints or correspondence: Dr. 34th St. Civic Center Blvd., PA 19104. Search for other works by this author on: Oxford Academic PubMed Google Scholar Renu Gupta, Gupta Thomas...
In this study, we have explored the relationship between interleukins and human basophil activation. Previous studies by ourselves others found that recombinant (rh) IL-3 causes histamine release. The ability to release has also been claimed for IL-1 but cannot confirm this. experiments with basophils of 29 donors (excluding one D2O responder), 100 ng/ml rhIL-1 alpha was 1.3 +/- 1% (SEM), whereas beta, it 0.8 1%. Both -1 beta were used at concentrations 0.01 1000 without causing Neither...
To compare peri- and postoperative outcomes complications of laparoscopic vs. robotic-assisted surgical staging for women with endometrial cancer at two established academic institutions.Retrospective chart review all that underwent total hysterectomy pelvic para-aortic lymphadenectomy by or approach over a four-year period three surgeons institutions. Intraoperative were measured. Secondary included operative time, blood loss, transfusion rate, number lymph nodes retrieved, length hospital...
Abstract Background Though obesity has been said to be associated with a number of malignancies including cervical cancer, its association intraepithelial neoplasia (CIN) is still contentious issue. This study was designed determining the prevalence and between CIN. Methods an unmatched case control study, involving women (cases) those negative for lesions or malignancy (controls) at cancer clinic Mbarara Regional Referral Hospital, in south-western Uganda, April November 2022. Cases...
Objective. This study investigates geographic variation in chemotherapy utilization for ovarian cancer both absolute and relative terms examines area characteristics associated with this variation. Data Sources. Surveillance, Epidemiology, End Results (SEER) Medicare data from 1990 to 2001 patients over 65 a diagnosis of between 1999. Chemotherapy within year was identified by billing codes. The hospital referral region (HRR) represents the unit analysis. Study Design. A logit model...
Purpose: To determine whether (1) black and white women with endometrial cancer were treated by different surgical specialties in types of hospitals (2) differences specialty hospital type contributed to racial survival. Methods: Retrospective cohort study 12,307 aged 65 years older who underwent treatment between 1991 1999 the 11 Surveillance Epidemiology End Results registries. Results: Black more likely have a gynecologic oncologist perform their surgery be at that higher volume, larger,...