Betül Sevınır

ORCID: 0000-0002-3232-7652
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Research Areas
  • Neutropenia and Cancer Infections
  • Childhood Cancer Survivors' Quality of Life
  • Glioma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Head and Neck Surgical Oncology
  • Myasthenia Gravis and Thymoma
  • Autoimmune and Inflammatory Disorders Research
  • Bone health and treatments
  • Antibiotics Pharmacokinetics and Efficacy
  • Parvovirus B19 Infection Studies
  • Bone Tumor Diagnosis and Treatments
  • Cultural and Sociopolitical Studies
  • Sarcoma Diagnosis and Treatment
  • Testicular diseases and treatments
  • Adolescent and Pediatric Healthcare
  • Genetic and rare skin diseases.
  • Pituitary Gland Disorders and Treatments
  • Hepatitis B Virus Studies
  • Nosocomial Infections in ICU
  • Oral health in cancer treatment
  • Pharmacological Effects and Toxicity Studies
  • Vascular Malformations and Hemangiomas
  • Hematological disorders and diagnostics
  • Hepatitis C virus research
  • Ocular Oncology and Treatments

Bursa Uludağ Üni̇versi̇tesi̇
2012-2024

Sağlık Bilimleri Üniversitesi
2023

İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
2023

Bursa Technical University
2023

Acıbadem Adana Hospital
2023

Izmir University
2023

Adli Tıp Kurumu
2020

Trakya University
2019

İstanbul Eğitim ve Araştırma Hastanesi
2012

Pediatrics and Genetics
2003

Catheter-associated bloodstream infections (CABSIs) are common complications encountered with cancer treatment. The aims of this study were to analyze the factors associated recurrent infection and catheter removal in pediatric hematology-oncology patients. All cases CABSIs patients attending Department Pediatric Hematology-Oncology between January 2008 December 2010 reviewed. A total 44 episodes CABSIs, including multiple involving same catheter, identified 31 children cancer. overall rate...

10.3109/08880018.2013.772683 article EN Pediatric Hematology and Oncology 2013-03-04

The objective of the present study was to determine type, frequency, reason why complementary and alternative medicine (CAM) treatments are used, factors related with their use, effects CAM usage on long-term survival. Families a total 120 children cancer between 0–18 years age, including 50 (41.7%) girls 70 (58.3%) boys, participated in our study. authors found that 88 patients (73.3%) used at least one method, most common (95.5%) which biologically based therapies. Most frequently...

10.3109/08880018.2012.670368 article EN Pediatric Hematology and Oncology 2012-04-27

Disorders of sex development are defined as conditions in which the chromosomal, gonadal, and anatomic is discordant. Patients usually present with atypical appearing genitalia. In assessment neonates disorders development, first, it important to determine whether this situation requires prompt evaluation, then karyotype, hormone levels, underlying etiology should be determined soon possible. All these procedures performed guidance a multidisciplinary team reference centers. As physical...

10.5152/turkpediatriars.2018.01818 article EN Türk Pediatri Arşivi 2019-02-22

The national protocol aimed to improve the outcome of high risk neuroblastoma patients by high-dose chemotherapy and stem cell rescue with intensive multimodal therapy.After 6 induction cycles, without disease progression were nonrandomly (by physicians' and/or parent's choices) allocated into two treatment arms, which designed continue conventional (CCT), or myeloablative therapy autologous (ASCR).Fifty-six percent (272 patients) was evaluated as risk. Response rate 71%. Overall event-free...

10.4103/0973-1482.183205 article EN Journal of Cancer Research and Therapeutics 2017-01-01

In this study, we aimed to determine serum adrenomedullin levels and compare them with of C-reactive protein (CRP) procalcitonin (PCT). Cancer patients aged 0–18 years who experienced febrile neutropenia attacks were included in the study. Adrenomedullin, CRP, PCT analyzed at admission, day 3, days 7–10 later. Fifty episodes that developed 37 The mean age was 7.5 ± 4.7 (1–18) years. had leukemia (73%), solid tumors (19%), lymphoma (8%). percentages clinically documented infection (CDI),...

10.3109/08880018.2015.1057310 article EN Pediatric Hematology and Oncology 2015-08-13

The aim of this case–control study was to compare the dental health a group long-term survivors childhood cancer with that age- and gender-matched healthy controls. All children who had been progress- and/or disease-free for at least 5 years were selected. Caries indices permanent dentition (DMF/T) primary (dmf/t) calculated. Past data collected from medical records read separately by one authors. mean age subjects initial diagnosis disease 4.3 ± 0.3 yr (range 0.5–14 yr). time lapse...

10.1080/08880010802237849 article EN Pediatric Hematology and Oncology 2008-01-01

Hepatoblastoma, an embryonal tumor, is one of the most common primary liver tumors in childhood. It secretes human chorionic gonadotropin (hCG), which can cause precocious puberty (PP). Herein, we present a case with PP who had enlarged penile size noticed during diagnosis hepatoblastoma. Laboratory examination revealed increased testosterone, alpha-fetoprotein (AFP), and hCG levels. Serum follicle-stimulating hormone (FSH) luteinizing (LH) levels were within prepubertal ranges. The...

10.4274/jcrpe.v1i6.281 article EN cc-by-nc-nd Journal of Clinical Research in Pediatric Endocrinology 2009-11-19

Anemia, which is a common problem in cancer patients, has negative effect on survival by decreasing the efficacy of chemotherapy and particularly radiotherapy, as well impairing quality life (QoL) patients. Recombinant human erythropoietin (rHuEPO) decreases patient's need for transfusions increases their QoL. The aim this study was to evaluate weekly single-dose EPO treatment transfusion rates, QoL, hemoglobin (Hb) levels. In addition, patients were followed up long period assess impact...

10.3109/08880018.2011.570857 article EN Pediatric Hematology and Oncology 2011-06-27

Abstract: Neurocutaneous melanosis (NCM) is rare and characterized by the proliferation of melanocytes in central nervous system. A 6‐day‐old infant boy was referred to our department with giant congenital melanocytic nevi convulsions. On physical examination patient had a black‐brown pigmented nevus covering his face, neck, scalp, shoulders, back, chest, abdomen. Numerous satellite lesions were noted on upper extremities. In right bulbar conjunctiva, brown plaque present. Magnetic resonance...

10.1046/j.1525-1470.2003.20412.x article EN Pediatric Dermatology 2003-07-01

The objective of this study was to compare the effectiveness piperacillin-tazobactam (PIP/TAZO) plus amikacin (AMK) (PIP/TAZO+AMK) versus cefoperazone-sulbactam (CS) AMK (CS+AMK) for treatment febrile neutropenia (FN) in children with cancer. designed prospectively and randomized 0- 18-year-old lymphoma or solid tumor who were hospitalized FN diagnosis. Consecutively patients received either PIP/TAZO 360 mg/kg/day 4 doses 15 3 CS 100 intravenously. Treatment modification defined as any...

10.3109/08880018.2012.756565 article EN Pediatric Hematology and Oncology 2013-01-09

Bone mineral density (BMD) and anthropometric measurements in pediatric cancer patients were evaluated compared at early late posttreatment periods. Sixty-six who recovered completely following treatment longer than least a 6-month period included the study. Patients cross-sectionally prospectively with regard to BMD twice; first being mean of 2.62 ± 1.44 years second 6.55 1.71 after completion treatment. Rates osteoporosis osteopenia or evaluation 25.8% 39.4% 10.6% 19.7%, respectively. Mean...

10.3109/08880018.2011.603819 article EN Pediatric Hematology and Oncology 2011-09-21

Introduction: The aim of this study is to evaluate late side effects that affect quality life in children with sacrococcygeal teratoma (SCT).Patients and methods: patients SCT were evaluated retrospectively. data expressed by percentage the subgroups compared statistically.Results: A total 40 identified median age 12 days (range: 1 day-14.6 years), 27 whom analyzed urodynamic available for 24 anal manometric evaluations 20. Chronic constipation need laxative was reported (7/27) 25.9%, fecal...

10.1080/08880018.2018.1504151 article EN Pediatric Hematology and Oncology 2018-10-22

Varicella is a primary infection, occurring in persons with no specific antibody or cell-mediated immunity to varicellazoster virus (VZV). tends be mild disease otherwise healthy children. However, immunocompromised individuals the mortality rate and frequency of serious complications are greatly increased, despite availability passive immunization antiviral chemotherapy.1 The predisposition development severe varicella results from impairment immune response varicella-zoster rather than...

10.1097/00006454-199602000-00015 article EN The Pediatric Infectious Disease Journal 1996-02-01

Tumors of the urinary bladder are rare in children and nearly all them mesodermal origin. Herein we report a case transitional cell carcinoma 13-year-old boy who presented after blunt abdominal trauma. It should be remembered that hematuria could develop trauma children, for reasons other than itself (e.g. tumors tract).

10.1111/j.1442-2042.2005.01035.x article EN International Journal of Urology 2005-03-01

A case of POF in the maxilla a 10-year-old child is presented.This reported view its absence and difficulty diagnosis due to radiological resemblance lymphoma osteosarcoma, further aggravated by clinical scenario.

10.4172/2161-1122.1000110 article EN Dentistry 2011-01-01

In low-grade glioma, metastasis is rarely seen. Few cases of leptomeningeal dissemination have been reported in children. Vertebral bone has not so far. Herein described the case a pediatric patient with diagnosis pilocytic astrocytoma, and detected at time diagnosis, who then received radiotherapy chemotherapy upon development vertebral during treatment.

10.1111/ped.13121 article EN Pediatrics International 2016-11-13

ÖzÇocukluk çağında torakal kitlelerin önemli bir kısmı mediastende görülür.Mediastende farklı dokulardan köken alan kitleleri daha kolay tanımlamak için mediasten üst ve alt; alt de ön, orta arka olarak bölümlere ayrılır.Mediasten malign veya non-malign olabilir.Kitlelerin büyüklüklerine bulunduğu yere göre belirtileri değişebilir.Ön mediastendeki kitleler çok hava yollarına ana damarlara yapabileceği basılar, olası intramedüller uzanım sinir köklerine basılar nedeniyle önem...

10.4274/jcp.81905 article TR Güncel Pediatri 2016-04-01

e15075 Background: Cisplatin induced ototoxicity (CIO), with permanent hearing loss is observed in >60% pediatric patients Turkey. PEDMARK (Sodium Thiosulfate anhydrous) reduced the risk of CIO cases non-metastatic solid tumors Phase 3 studies (SIOPEL 6 & COG ACCL0431). We aimed to evaluate investigational product provided for via a National Compassionate Use Treatment Protocol (CUP) Methods: Patients (1 month <18 years) localized, nonmetastatic tumor, standard-risk hepatoblastoma...

10.1200/jco.2024.42.16_suppl.e15075 article EN Journal of Clinical Oncology 2024-06-01
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