Fangyan Zhong

ORCID: 0000-0002-3244-4023
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About
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Research Areas
  • Head and Neck Cancer Studies
  • RNA modifications and cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Breast Cancer Treatment Studies
  • Advanced Radiotherapy Techniques
  • Effects of Radiation Exposure
  • DNA Repair Mechanisms
  • Lung Cancer Diagnosis and Treatment
  • Cancer-related molecular mechanisms research
  • Cancer Immunotherapy and Biomarkers
  • Metabolomics and Mass Spectrometry Studies
  • Lung Cancer Treatments and Mutations
  • Epigenetics and DNA Methylation
  • Advances in Oncology and Radiotherapy
  • Artificial Intelligence in Healthcare and Education
  • Cancer-related Molecular Pathways
  • Cancer, Hypoxia, and Metabolism
  • Cleft Lip and Palate Research
  • Esophageal Cancer Research and Treatment
  • Frailty in Older Adults
  • Cancer, Lipids, and Metabolism
  • Viral-associated cancers and disorders
  • Medical Imaging and Analysis
  • Head and Neck Surgical Oncology

Jiangxi Provincial Cancer Hospital
2022-2025

Nanchang University
2019-2024

First Affiliated Hospital of Nanchang University
2021

Versus Arthritis
2021

National and Kapodistrian University of Athens
2021

Weatherford College
2021

This study aimed to construct a signature of N6-methyladenosine (m6A) regulator-related genes that could be used for the prognosis head and neck squamous cell carcinoma (HNSCC) clarify molecular immune characteristics benefits checkpoint inhibitor (ICI) therapy using prognostic define subgroups HNSCC. showed eighteen m6A regulators were abnormally expressed in Cancer Genome Atlas (TCGA) HNSCC tissues compared with those normal tissues. We constructed 12 Cox risk model, combined least...

10.3389/fimmu.2022.809872 article EN cc-by Frontiers in Immunology 2022-02-03

Rationale Nasopharyngeal carcinoma (NPC) is a malignant tumor that endemic in Southeast Asia, North Africa, and southern China. There an urgent need for effective early diagnosis treatment of this disease since NPC currently often detected at advanced stages. Methods To reveal the underlying metabolic mechanisms discover potential diagnostic biomarkers NPC, we employed ultrahigh‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry (UHPLC‐Q‐TOF‐MS)...

10.1002/rcm.9469 article EN Rapid Communications in Mass Spectrometry 2023-01-03

Abstract Background and Purpose To identify anatomic prognostic factors their potential roles in refining M1 classification for de novo metastatic nasopharyngeal carcinoma (M1‐NPC). Materials Methods All M1‐NPC treated with chemotherapy and/or radiotherapy between 2010 2019 from two centers (training validation cohort) were included. The value of disease extent involved organs overall survival (OS) assessed by several multivariable analyses (MVA) models. A new was proposed validated a...

10.1002/cam4.6816 article EN cc-by Cancer Medicine 2023-12-01

Hepatocellular carcinoma (HCC) is one of the common cancers with a high incidence and mortality. The human replication factor C (RFC) family contains 5 subunits that play an important role in DNA damage repair. RFCs are abnormally expressed variety cancers; some them differentially HCC tissues related to tumor growth. However, expression, prognostic value, effect targets whole RFC still unclear. To address these issues, we performed multidimensional analysis patients by Oncomine, UALCAN,...

10.1177/1176934321994109 article EN cc-by-nc Evolutionary Bioinformatics 2021-01-01

Objective: This study aims to delineate the current research hotspots and developmental trajectories of artificial intelligence (AI) in nasopharyngeal carcinoma (NPC) through bibliometric analysis, offering visualized insights scholars clinicians. Methods: We utilized Web Science Core Collection database collate articles pertinent AI applications NPC. The extracted data were processed using CiteSpace, VOSviewer, R-Bibliometrix for analysis knowledge mapping, facilitating a comprehensive...

10.2139/ssrn.4749861 preprint EN 2024-01-01

133 Background: To calculate the percentage of tumor-infiltrating lymphocytes (TILs) in nasopharyngeal carcinoma (NPC) using deep-learning (DL) algorithms based on digital pathology images and differentiate outcome. Methods: We recruited 435 patients with primary non-metastatic NPC 63 de novo metastatic received immunotherapy. TIL DL was calculated convolutional neural network model, its ability to metastasis risk independent prognostic value were analyzed Kaplan–Meier survival multivariate...

10.1200/jco.2024.42.23_suppl.133 article EN Journal of Clinical Oncology 2024-08-10

We explored the dosimetric efficacy of abdominal deep inspiration breath hold (aDIBH) technique using an audio-guided device in patients with left breast cancer undergoing postoperative adjuvant radiotherapy compared to free breathing (FB).

10.1186/s43046-024-00234-2 article EN cc-by Journal of the Egyptian National Cancer Institute 2024-09-23

Geriatric 8 score (G8) was an independent prognostic factor for survival and toxicities in various malignancies, but it has never been tested nasopharyngeal carcinoma (NPC).To evaluate the value of G8 predicting elderly patients with NPC.Patients NPC aged ≥70 who received intensity-modulated radiation therapy were recruited into this study. The overall (OS), progression-free (PFS), locoregional recurrence rate (LRR), distant metastasis (DMR) between > 14 ≤ calculated using Kaplan-Meier...

10.1080/00016489.2023.2190769 article EN cc-by-nc-nd Acta Oto-Laryngologica 2023-03-30

Abstract Purpose To evaluate the outcomes in elderly patients with nasopharyngeal carcinoma (NPC) treated by intensity modulated radiation therapy (IMRT). Methods Patients NPC aged ≥ 70 years old who received intensity-modulated 60 Gy were recruited into this study. The overall survival (OS), progression-free (PFS), cancer-specific (CSS), locoregional recurrence-free rate (LRFR) and distant metastasis-free (DMFR) calculated using Kaplan–Meier method. Cox proportional hazards model was...

10.1007/s44178-023-00047-8 article EN cc-by Holistic Integrative Oncology 2023-07-06
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