Junjun Chen

ORCID: 0000-0002-3783-6085
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Climate Change and Health Impacts
  • Pregnancy and preeclampsia studies
  • Birth, Development, and Health
  • Landslides and related hazards
  • Child Nutrition and Feeding Issues
  • Gestational Diabetes Research and Management
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Tactile and Sensory Interactions
  • Thermoregulation and physiological responses
  • Hair Growth and Disorders
  • Pediatric Hepatobiliary Diseases and Treatments
  • Wound Healing and Treatments
  • Autism Spectrum Disorder Research
  • Skin Protection and Aging
  • Land Use and Ecosystem Services
  • Epigenetics and DNA Methylation
  • Rock Mechanics and Modeling
  • Fetal and Pediatric Neurological Disorders
  • Intestinal Malrotation and Obstruction Disorders
  • Cancer-related gene regulation
  • Evaluation Methods in Various Fields
  • Educational Reforms and Innovations
  • Hip and Femur Fractures

Johns Hopkins University
2022-2025

Nanchang University
2022-2024

East China Normal University
2024

China University of Mining and Technology
2024

Johns Hopkins Medicine
2023

Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2022

Wenzhou Medical University
2022

Peking University
2022

Jiangxi Provincial Cancer Hospital
2022

Dongguan People’s Hospital
2017

Tissue injury induces metabolic changes in stem cells, which likely modulate regeneration. Using a model of organ regeneration called wound-induced hair follicle neogenesis (WIHN), we identified skin-resident bacteria as key modulators keratinocyte metabolism, demonstrating positive correlation between bacterial load, glutamine and Specifically, through comprehensive multiomic analysis single-cell RNA sequencing murine skin, show that bacterially induced hypoxia drives increased metabolism...

10.1126/sciadv.abo7555 article EN cc-by-nc Science Advances 2023-01-04

The human hand's hybrid structure combines soft and rigid anatomy to provide strength compliance for versatile object grasping. Tactile sensing by skin mechanoreceptors enables precise dynamic manipulation. Attempts replicate the hand have fallen short of a true biomimetic robotic with tactile sensing. We introduce natural prosthetic composed joints endoskeleton three independent neuromorphic layers inspired physiology. Our innovative design capitalizes on strengths both robots, enabling...

10.1126/sciadv.adr9300 article EN cc-by-nc Science Advances 2025-03-05

Background and objectives Pulmonary nocardiosis (PN) is a rare but life-threatening disease that caused by Nocardia spp. The aim of this study was to characterize the common risk factors, clinical features, imaging findings, treatment outcomes PN, which are useful for an early diagnosis patient management. Methods From January 2009 June 2013, retrospective performed on all PN cases were diagnosed at our hospital. Results included 17 patients who with PN. Of these patients, 4 developed...

10.1371/journal.pone.0090724 article EN cc-by PLoS ONE 2014-03-03

This study aimed to construct a signature of N6-methyladenosine (m6A) regulator-related genes that could be used for the prognosis head and neck squamous cell carcinoma (HNSCC) clarify molecular immune characteristics benefits checkpoint inhibitor (ICI) therapy using prognostic define subgroups HNSCC. showed eighteen m6A regulators were abnormally expressed in Cancer Genome Atlas (TCGA) HNSCC tissues compared with those normal tissues. We constructed 12 Cox risk model, combined least...

10.3389/fimmu.2022.809872 article EN cc-by Frontiers in Immunology 2022-02-03

The relationship between first-trimester GWG ( T 1 GWG) and risk of hypertensive disorders pregnancy (HDP) remained uncertain. This study aimed to investigate the association de novo HDP. Meanwhile, we explored mediated effect constructed an early category evaluate predictive capacity for was defined as weight difference 13 ± gestational weeks pre-conception. HDP group having diagnosis HDP, including hypertension or pre-eclampsia (PE) during current pregnancy. Early according within each...

10.3389/fnut.2022.862323 article EN cc-by Frontiers in Nutrition 2022-04-13

Background Particulate matter (PM) is detrimental to the respiratory and circulatory systems. However, no study has evaluated lag effects of weekly exposure fine PM during period from preconception delivery on risk hypertensive disorders pregnancy (HDPs). Objective We set out investigate effect windows HDPs a scale. Methods Data women with de novo normotensive pregnant who were part Peking University Retrospective Birth Cohort, based hospital information system Tongzhou district, obtained...

10.2196/41442 article EN cc-by JMIR Public Health and Surveillance 2022-12-01

Effectively identifying high-risk patients with de novo hypertensive disorder of pregnancy (HDP) is required to enable timely intervention and reduce adverse maternal perinatal outcomes. Electronic medical record pregnant women HDP were extracted from a birth cohort in Beijing, China. The outcomes included fetal morbidities, mortality, or any other complications. A multitude machine learning statistical methods employed develop two prediction models, one for complications the deteriorations....

10.3390/healthcare10112307 article EN Healthcare 2022-11-18

10.21037/qims-22-37 article CA Quantitative Imaging in Medicine and Surgery 2022-06-08

Reading has been playing an important role in learning English. In April of 2022, the new English Curriculum Standard also stated significance and value early reading. It means we have stepped into a era core competences, developing competencies based on extensive reading activities. can develop ESL students’ linguistic abilities, cultivate their culture consciousness advance thinking quality improve ability. And these abilities are key dimension cultivating students' competences. Strategies...

10.23977/curtm.2024.070123 article EN Curriculum and Teaching Methodology 2024-01-01

133 Background: To calculate the percentage of tumor-infiltrating lymphocytes (TILs) in nasopharyngeal carcinoma (NPC) using deep-learning (DL) algorithms based on digital pathology images and differentiate outcome. Methods: We recruited 435 patients with primary non-metastatic NPC 63 de novo metastatic received immunotherapy. TIL DL was calculated convolutional neural network model, its ability to metastasis risk independent prognostic value were analyzed Kaplan–Meier survival multivariate...

10.1200/jco.2024.42.23_suppl.133 article EN Journal of Clinical Oncology 2024-08-10

Background Despite mounting evidence linking neurological diseases with climate change, the link between autism spectrum disorder (ASD) and global warming has yet to be explored. Aims To examine relationship incidence of ASD from 1990 2019 estimate trajectory 2020 2100 globally. Method We extracted meteorological data TerraClimate 2019. association temperature variation, we adopted a two-stage analysis strategy using generalised additive regression model. Additionally, projected future under...

10.1192/bjo.2024.790 article EN cc-by-nc-nd BJPsych Open 2024-11-01

Background: Gestational hypertension and pre-eclampsia are the major de novo subtypes of hypertensive disorder pregnancy (de HDP) that can pose severe health problems to pregnant woman her fetus. Therefore, effectively identifying high-risk patients with HDP is required enable timely intervention reduce adverse maternal perinatal outcomes.Method: Data women satisfied other inclusion criteria were extracted from a 7-year birth cohort (2012-2019) at child care center in Beijing, China. The...

10.2139/ssrn.4080972 article EN SSRN Electronic Journal 2022-01-01

特殊形貌磷酸锆钠粉体的制备与表征 陈军军, 王 晶, 惠 香 (大连交通大学 辽宁省无机超细粉体制备及应用重点实验室, 大连 116028) 摘 要: 采用水热法、以八水合氧氯化锆和多聚磷酸钠为原料、水为介质, 一步制备出了单相 Na 2 Zr(PO 4 ) 粉体。利 用 XRD、SEM、TG-DSC 等检测方法, 系统地考察了水热条件和煅烧温度对磷酸锆钠粉体微观结构的影响。结果 表明, 原料摩尔配比为 n(ZrOCl ⋅8H O) : n(Na 5 P 3 O 10 )=1:2、无需调变 pH 值的中性条件下, 于 140℃水热 14 h, 即可 制得分散性较好、尺寸较均一、由片组装而成的类线团形貌的 粉体; 适当延长水热时间和提高水热温 度均有利于粉体的形成, 且温度越高

10.15541/jim20130602 article ZH-CN Journal of Inorganic Materials 2014-01-01

Objective To investigate the effects of diagnosis fetal ventricular septal defect (VSD) on outcomes. Methods From January 1, 2014 to November 30, 2016, 23 041 fetuses 011 pregnant women in second trimester pregnancy who were examined by systematic prenatal ultrasonography (grade Ⅲ) Dongguan People′s Hospital Affiliated Southern Medical University, chosen as research subjects. After obstetrician comprehensive assessments and consultations with wishes family members, VSD fetus diagnosed...

10.3877/cma.j.issn.1673-5250.2017.06.018 article EN 2017-12-01

<sec> <title>BACKGROUND</title> Particulate matter (PM) is detrimental to the respiratory and circulatory system. However, no study was found evaluating lag effects of weekly exposure fine PM from preconception delivery on risk hypertensive disorders pregnancy (HDP). </sec> <title>OBJECTIVE</title> To investigate effect windows PMs HDP in week scale. <title>METHODS</title> De novo normotensive pregnant women this were Peking University Retrospective Birth Cohort Tongzhou based hospital...

10.2196/preprints.41442 preprint EN 2022-07-26
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