- COVID-19 epidemiological studies
- COVID-19 and Mental Health
- Virology and Viral Diseases
- Infection Control and Ventilation
- Hip disorders and treatments
- Respiratory viral infections research
- Lower Extremity Biomechanics and Pathologies
- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
- Birth, Development, and Health
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Food Allergy and Anaphylaxis Research
- Viral Infections and Outbreaks Research
- Hepatitis Viruses Studies and Epidemiology
- Breastfeeding Practices and Influences
- Syphilis Diagnosis and Treatment
- COVID-19 Pandemic Impacts
- Orthopaedic implants and arthroplasty
- Cancer Risks and Factors
- Herpesvirus Infections and Treatments
- Bone and Joint Diseases
- COVID-19 and healthcare impacts
- Influenza Virus Research Studies
Center for Disease Dynamics, Economics & Policy
2021-2025
Pennsylvania State University
2021-2025
Hospital for Sick Children
2019-2025
Museum of Heilongjiang Province
2021
Nuffield Orthopaedic Centre
2020
University of Oxford
2017-2020
London School of Hygiene & Tropical Medicine
2020
Office of Infectious Diseases
2019
Non-pharmaceutical public health measures (PHMs) were central to pre-vaccination efforts reduce Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) exposure risk; heterogeneity in adherence placed bounds on their potential effectiveness, and correlation adoption makes assessing the impact attributable an individual PHM difficult. During Fall 2020 semester, we used a longitudinal cohort design university student population conduct behavioral survey of intention adhere PHMs, paired...
Infants are often assumed to be immune measles through maternal antibodies transferred during pregnancy and, in many countries, receive their first measles-containing vaccine at 12 15 months. Immunity may wane before this time measles-eliminated settings, placing infants risk for and complications. We investigated humoral immunity <12 months of age Ontario, Canada.We selected sera collected a tertiary pediatric hospital from who were born ≥37 weeks' gestational age. excluded with conditions...
Abstract Objective: In this study, we aimed to capture perspectives of healthcare workers (HCWs) on coronavirus disease 2019 (COVID-19) and infection prevention control (IPAC) measures implemented during the early phase COVID-19 pandemic. Design: A cross-sectional survey HCWs. Participants: HCWs from Hospital for Sick Children, Toronto, Canada. Intervention: self-administered was distributed We analyzed factors influencing HCW knowledge self-reported use personal protective equipment (PPE),...
The aim of this study was to examine the real time in vivo kinematics hip patients with cam-type femoroacetabular impingement (FAI).A total 50 (83 hips) underwent 4D dynamic CT scanning hip, producing osseous models pelvis and femur being moved through flexion, adduction, internal rotation. location size cam deformity its relationship angle flexion pelvic tilt, position were recorded.In these FAI, there significant correlation between alpha point (mean 41.36°; 14.32° 57.95°) (R = -0.5815 p <...
Abstract Background Returning university students represent large-scale, transient demographic shifts and a potential source of transmission to adjacent communities during the COVID-19 pandemic. Methods In this prospective longitudinal cohort study, we tested for IgG antibodies against SARS-CoV-2 in non-random residents living Centre County prior Fall 2020 term at Pennsylvania State University following conclusion term. We also report seroprevalence collected end Results Of 1313 community...
Abstract Returning university students represent large-scale, transient demographic shifts and a potential source of transmission to adjacent communities during the COVID-19 pandemic. In this prospective longitudinal cohort study, we tested for IgG antibodies against SARS-CoV-2 in non-random residents living Centre County prior Fall 2020 term at Pennsylvania State University following conclusion term. We also report seroprevalence collected end Of 1313 community participants, 42 (3.2%) were...
Objective The aim of this study was to determine the effects activity and cam morphology on cartilage composition during adolescence investigate development with age. Design Cross-sectional observational cohort individuals from football club academies an age-matched control population, aged 9 18 years. Assessments included questionnaires T2-mapping hips. Primary imaging outcome measures were T2 relaxation time acetabular femoral cartilage, average alpha angle, lateral epiphyseal extension....
Pertussis causes significant morbidity and mortality in infants aged <6 months. Maternal pertussis vaccination during pregnancy has been recommended Canada since 2018 to reduce these negative outcomes. In the absence of routine immunization coverage data, our objective was evaluate uptake Toronto, Canada.We recruited mother-infant pairs at The Hospital for Sick Children, between 2020. We performed logistic regression examine associations demographics self-reported vaccination.76/243 mothers...
To investigate maternal antibody levels to varicella in infants <12 months of age Ontario, Canada.In this study, we included specimens from age, born at ≥37 weeks gestational who had sera collected The Hospital for Sick Children (Toronto, Canada) between 2014-2016. We tested using a glycoprotein-based enzyme-linked immunosorbent assay (gpELISA). measured susceptibility (antibody concentration <150mIU/mL) and mean concentration, assessed the probability one 11 multivariable logistic...
Mathematical models are established tools to assist in outbreak response. They help characterise complex patterns disease spread, simulate control options public health authorities decision-making, and longer-term operational financial planning. In the context of vaccine-preventable diseases (VPDs), vaccines one most-cost effective response interventions, with potential avert significant morbidity mortality through timely delivery. Models can contribute design vaccine by investigating...
Non-pharmaceutical public health measures (PHMs) were central to pre-vaccination efforts reduce Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) exposure risk; heterogeneity in adherence placed bounds on their potential effectiveness, and correlation adoption makes assessing the impact attributable an individual PHM difficult. During Fall 2020 semester, we used a longitudinal cohort design university student population conduct behavioral survey of intention adhere PHMs, paired...
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