A5083094349- Crystallization and Solubility Studies
- Chemical and Physical Properties in Aqueous Solutions
- Analytical Chemistry and Chromatography
- Pharmacological Effects of Natural Compounds
- CAR-T cell therapy research
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Calcium Carbonate Crystallization and Inhibition
- Drug Solubulity and Delivery Systems
- Ionic liquids properties and applications
- Virus-based gene therapy research
- Ga2O3 and related materials
- ZnO doping and properties
- Advanced Photocatalysis Techniques
- Cancer Research and Treatments
Yangzhou University
2018-2023
Chongqing University of Technology
2019
Lanzhou University
2019
Methanol (n-propanol, isopropanol, and propylene glycol) water were mixed in different proportions to form four solvents, which applied dissolve bifonazole. The mole fraction of bifonazole was determined by the isothermal dissolution equilibrium technique within T = 278.15–318.15 K P 101.1 kPa under condition that system reached equilibrium. increase ratio organic solvent solvents temperature promoted solubility formed mixing methanol most beneficial for all solution systems at same...
The equilibrium solubility of 4-amino-2,6-dimethoxypyrimidine in different kinds binary mixed solvents—methanol + water (283.15–323.15 K), ethanol isopropanol and DMF K)—was measured by a dissolution technique under p = 101.1 kPa. experimental value has certain functional relationship with temperature the mass fraction methanol (ethanol, isopropanol, DMF). Within all fractions organic solvents temperature, was more soluble system than other three systems. Besides, calculated thermodynamic...
The equilibrium solubility (mole fraction) of difenoconazole in methanol, ethanol, n-propanol, isopropanol, N,N-dimethylformamide (DMF), acetonitrile, acetone, propylene glycol (PG), ethylene (EG), and water methanol/ethanol/isopropanol/PG + was measured by isothermal saturation method at 278.15–323.15 K under 101.2 kPa. pure solvents increased with increasing temperature, the mixed proportional to temperature ratio cosolvents. correlated Apelblat, NRTL, λh models. Jouyban-Acree (JA),...
Four liquid mixtures formed by mixing water and four organic solvents (methanol, ethanol, ethylene glycol, N,N-dimethylformamide (DMF)) in different ratios were used as solvents, fenbendazole was a solute. The concentration of the solute within T = 283.15–328.15 K mixed determined static techniques at p 101.1 kPa. experimental solubility obviously affected solution system temperature solvent concentration. High high beneficial to dissolution solutes. Conversely, low hinder dissolution. In...
The equilibrium solubility of 6-bromo-2-methylquinoline in various binary blends [ethanol/isopropanol/N,N-dimethylformamide (DMF)/methanol + water] and ten monosolvents (methanol, ethanol, n-propanol, isopropanol, ethyl acetate, toluene, acetone, acetonitrile, DMF, water) was studied by the isothermal method at 278.15–323.15 K under 101.2 kPa. Among pure solvents, maximum mole fraction obtained toluene (3.318 × 10–2), followed acetate (2.991 acetone (2.764 acetonitrile (2.528 DMF (2.220...
The equilibrium solubility is the basis of purification and further theoretical studies biapenem. In this work, biapenem in 10 pure solvents (methanol, ethanol n-propanol, isopropanol, acetone, N,N-dimethylformamide (DMF), acetonitrile, dimethyl sulfoxide (DMSO), N-methyl pyrrolidone (NMP), ethyl acetate) solvent mixtures (ethyl acetate + methanol) was measured by using a static method at temperatures from 283.15 to 323.15 K, p = 101.2 kPa. To sum up, highest NMP lowest acetone. high low...
In this study, the moxidectin solubility in four kinds of aqueous cosolvent mixtures methanol + water, ethanol isopropanol and ethylene glycol (EG) water was determined by gravimetric method at investigated temperatures 278.15–323.15 K under 101.2 kPa. All cosolvents (methanol, ethanol, isopropanol, EG) displayed good dissolving capability, order from high to low mole fraction scale is as follows: (0.2229, 323.15 K) > (0.1053, (4.552 × 10–2, EG (2.103 (2.491 10–5, K). From data obtained for...
Water as an auxiliary solvent is added to various alcohol solvents (methanol, ethanol, and isopropanol) N,N-dimethylformamide (DMF) form a variety of liquid mixtures, which are divided into different types according proportions. Starting from pure water, 0.1 mass fraction organic at time until the ratio 1. The abovementioned mixtures used dissolve halosulfuron-methyl 278.15–323.15 K under 101.2 kPa by means isothermal static technique. experimental solubility was calculated validated using...
This study used five pure solvents as raw materials and formed four sets of mixed by mixing methanol, ethanol, n-propanol, N,N-dimethyl formamide (DMF) in water. According to the principle isothermal static state, reaction temperature was increased from 278.15 323.15 K at 5 intervals. Under normal pressure (101.1 kPa) a constant mole fraction solute, equilibrium solubility thifensulfuron methyl obtained using high-performance liquid chromatography (HPLC). The influence on solute cannot be...
The efficacy of traditional therapies for oral carcinoma (OC) is limited. Oncolytic adenovirus, a novel strategy cancer therapy, shows potential use in OC treatment. However, its clinical application limited by pre-existing neutralizing antibodies. Thus, this study aimed to examine the new modified adenovirus against vitro and vivo.A multiple (MMAD) armed with IL-13 (MMAD-IL-13) was constructed, effect on Cal-27 cells examined. potency MMAD-IL-13 examined vivo. For experiment, CCK-8 kit used...
Water as an auxiliary solvent is added to various alcohol solvents (methanol, ethanol, ethylene glycol (EG)) and N,N-dimethylformamide (DMF) form a variety of liquid mixtures, which are divided into different types according proportions. Starting from pure water, 0.1 mass fraction organic at time, until the ratio 1. The above-mentioned mixtures used dissolve rimsulfuron 278.15–323.15 K under 101.1 kPa by means isothermal static technique. Considering that there many factors change...
The solubility of 2-amino-5-bromopyrazine in the co-solvent mixtures methanol, ethanol, isopropanol, and propylene glycol (PG) plus water 10 monosolvents (methanol, N,N-dimethylformamide (DMF), n-propanol, n-butanol, acetone, ethylene (EG), PG, water) was experimentally measured by isothermal method at 278.15–323.15 K under 101.2 kPa. temperature dominated trend pure mixed solvents, especially high temperatures had a positive effect on dissolution. For solvent system, maximum obtained DMF....
The solubility of 2-amino-3-chloropyrazine (ACPY) in some binary cosolvent mixtures (methanol, isopropyl alcohol, ethylene glycol (EG), N,N-dimethylformamide (DMF)) plus water and the experimental 2-amino-3,5-dibromopyrazine (ADPY) (ethanol + water), (isopropyl alcohol (EG (PG water) were all determined by isothermal saturation method from 278.15 K to 323.15 at 101.2 kPa. trend system temperature change solvent partner are both factors that affect dissolution. As goes higher, amount...
In the liquid dispersion structure, pure methanol, ethanol, isopropanol, and N,N-dimethyl formamide (DMF) play a major role in dissolution then water was added sequence for dilution to obtain system with different composition structures, concentration gradient between each mixed 0.1 (mass fraction). The drug nicorandil whose solubility be tested is it, using isothermal method, high temperature of 323.15 K as starting point an interval 5 low 278.15 K. pressure conditions did not require...
Diflufenican equilibrium solubilities when dissolved in a series of cosolvent mixtures (ethanol + water), (ethylene glycol, EG (propylene PG and (N,N-dimethyl formamide, DMF water) were determined analyzed by the isothermal saturation method from 278.15 to 323.15 K at an ambient pressure 101.2 kPa. Four pure organic solvents including ethanol, EG, PG, showed great dissolving capacity various aqueous cosolvency systems their solubility (in mole fraction) order was as follows: (2.983 × 10–3,...