In the practice of sleep medicine, first step is identification those patients at high risk for apnea. Nearly every physician and hospital has preferred methods screening. Many patient questionnaires or surveys as well some objective physical measurements have been suggested to predict presence Screening established, laboratory home testing are widely available. An early assessment with a examination can help direct treatment planning. The Friedman tongue position, lingual tonsil hypertrophy...

Circadian misalignment plays an important role in disease processes and can affect severity, treatment outcomes, even survivorship. In this study, we aim to investigate whether expression daily oscillation patterns of core circadian clock genes were disturbed patients with obstructive sleep apnea/hypopnea (OSA) syndrome. We performed real-time quantitative reverse transcriptase-polymerase chain reactions examine the nine leukocytes peripheral blood collected at 12 AM, 6 PM, PM from 133 OSA...

Objectives/Hypothesis Evaluate morbidity and mortality rates for patients with different levels of hyperparathyroidism (HPT) undergoing parathyroidectomy (PTX), specifically comparing primary to secondary tertiary hyperparathyroidism. Assess predictive factors increased mortality. Study Design Retrospective national database review. Methods Patients PTX, defined by Current Procedural Terminology codes 60500, 60502, 60505, the treatment HPT, were identified in American College Surgeons...

Objective To identify factors that may be associated with lingual tonsil hypertrophy (LTH). Study Design Case series chart review. Setting Tertiary academic center. Subjects and Methods Retrospective review identified 380 patients from August 2013 to April 2014 graded tonsils, documented during routine flexible laryngoscopy. Lingual tonsils were using a 0 4 scale: = complete absence of lymphoid tissue, 1 tissue scattered over tongue base, 2 covers entirety base limited thickness, 3 5 10 mm...

Objectives/Hypothesis To determine whether the Epworth Sleepiness Scale (ESS) can be improved by having a bed partner or roommate (“partner”) also fill out questionnaire; and to assess applicability of eight items in questionnaire, particularly an urban population. Study Design Retrospective chart review. Methods A retrospective review was conducted identify charts subjects with ESS score collected from both subject partner. Consensus scores were identified. Self‐reported compared consensus...

Objective To identify standard clinical parameters that may predict the presence and severity of obstructive sleep apnea/hypopnea syndrome (OSA). Design Case series with chart review. Setting Tertiary academic medical center. Subjects Methods A total 325 adult patients (274 men 51 women; mean age, 44.2 years) habitual snoring completed comprehensive polysomnography anthropometric measurements, including modified Mallampati grade (also known as updated Friedman's tongue position [uFTP]),...

Objective Whereas uvulopalatopharyngoplasty (UPPP) was the standard surgical procedure for obstructive sleep apnea prior to 2007, multilevel surgery has become since that time. This study compares morbidity and mortality rates of stand-alone UPPP with those includes UPPP. Methods Patients undergoing between 2007 2014 were identified in American College Surgeons National Surgical Quality Improvement Program database. defined by Current Procedural Terminology codes 42145 42950. Primary...

To develop an adequate model using reliable clinical and physical factors to predict pediatric obstructive sleep apnea/hypopnea syndrome (OSAS).Complete anthropometric measurements including BMI z score, tonsil size grading, updated Friedman tongue position (uFTP) were evaluated. Subjective assessments of symptoms/signs, snoring visual analog scale (VAS), nasal obstruction, mouth breathing, recorded.Eighty-eight children (57 boys 31 girls, mean age = 9.0 years) confirmed have OSAS by...

To compare peripapillary and macular vascular densities (PVDs MVDs) between patients with obstructive sleep apnea/hypopnea syndrome (OSA) control subjects symptoms of sleep-related breathing disorders only by swept-source optical coherence tomography angiography (OCTA).In this prospective study, 192 participants underwent a full-night polysomnography to determine OSA severity subsequently received OCTA measurements as well AngioTool software analysis.A total 146 (51 mild, 43 moderate, 52...

The increased risk of cardiovascular diseases owing to a high level serum homocysteine has been widely reported. Literature demonstrated that patients with obstructive sleep apnea/hypopnea syndrome (OSA) had higher than control group. This study aimed investigate the alteration levels in severe OSA receiving transoral robotic surgery (TORS).Retrospective chart review.Tertiary academic medical center.Data polysomnography (PSG) and before at least 3 months after were collected analyzed via...

Evidence has proved that high neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) were risk factors for cardiovascular comorbidities. The alterations of NLR PLR following obstructive sleep apnea (OSA) treatment under studied thus should be investigated. This study aimed to evaluate the changes inflammatory biomarkers including in severe OSA patients after surgical interventions upper airway, their relationships with improvements polysomnographic (PSG) parameters.This...

Objectives (1) Evaluate hearing outcomes of patients after planned malleus removal during ossicular chain reconstruction. (2) Analyze results for titanium (Ti) and hydroxyapatite (HA) total prostheses (TOPs) partial (POPs). (3) Compare Ti HA prostheses. Study Design Retrospective case series with chart review. Setting Tertiary health care organization. Subjects Methods A review was conducted 139 consecutive who presented chronic otitis media perforation (with or without cholesteatoma) were...

<h3>Importance</h3> This study adds to the literature on efficacy and low complication rates associated with minimally invasive, single-stage, multilevel surgery for Asian adults obstructive sleep apnea (OSA) whom conservative treatment had failed. Overall, our experience has produced results that make this procedure an option select patients snoring OSA. <h3>Objective</h3> To investigate effectiveness safety of anatomy-based, in OSA population. <h3>Design, Setting, Participants</h3>...

To assess 10-year data on subjective and objective improvements in patients with mild to moderate obstructive sleep apnea (OSA) after single-stage multilevel minimally invasive surgery.Case series chart review.Tertiary academic center.A review was conducted of 601 diagnosed OSA who were treated surgery from January 2005 2015. Patients a combination procedures that included various nasal procedures, palatal stiffening, radiofrequency tongue base reduction. Demographics parameters collected;...

Obstructive sleep apnea/hypopnea syndrome (OSA) could compromise oxygenation of the optic nerve and cause glaucomatous neuropathy; however, there were no studies to investigate changes visual function retinal microstructures in OSA patients after upper airway surgery. We aim assess sensitivity fiber layer thickness before surgery.This prospective single-blind study enrolled with from a tertiary academic medical center who had unsuccessful conservative therapy then underwent The referred for...

Obstructive sleep apnea/hypopnea syndrome (OSA) results in repeated oxygen desaturation, arousals, and episodic nocturnal activation of sympathetic nervous system during sleep. Untreated OSA is strongly associated with an increase cardio- cerebrovascular disorders, as well the damages ophthalmological microstructures. However, previous literature only simply studied association between ophthalmic disorders OSA. In present study, we first investigated alterations ocular surface tear film...

Objectives/Hypothesis To determine the effect of treatment obstructive sleep apnea (OSA) with custom‐made mandibular advancement devices (MADs) on C‐reactive protein (CRP) levels in patients apnea/hypopnea syndrome (OSAHS). Study Design Case series chart review. Methods Charts consecutive fitted for OSAHS between December 2011 and November 2012 were reviewed. Demographics such as age, sex, body mass index (BMI) collected. Prefitting postfitting polysomnograms Pre‐ posttreatment...

It is generally assumed that mouth opening decreases the hypopharyngeal cross-sectional area (HA) and tongue protrusion (TP) increases HA. We hypothesize a substantial number of patients do not exhibit this expected pattern.Prospective cohort conducted at tertiary academic center.With flexible fiberoptic scope in position, airway was visualized assessed 189 with closed. Patients were then asked to open neutral position (MOTN) determine effect on airway. The same methodology used compare MOTN...

To retrospectively study the effects of minimally invasive single-stage multilevel surgery (MISS MLS) for treating patients with obstructive sleep apnea/hypopnea syndrome (OSA) on quality life (QOL).All OSA obstruction who failed or refused continuous positive airway pressure (CPAP) treatment and then underwent Pillar implants temperature-controlled radiofrequency base tongue (RFBOT) were enrolled. The subjective symptoms QOL (SF-36 Taiwan Standard Version 1.0) parameters collected...

The aim of this study was to evaluate the effects upper airway surgery on daytime sleepiness in nonobese patients with obstructive sleep apnea/hypopnea syndrome (OSA).This retrospective included 121 consecutive adult OSA from a tertiary academic medical center. Patients who refused continuous positive pressure therapy, or whom it unsuccessful, and then underwent were enrolled. Evaluations excessive using Epworth Sleepiness Scale (ESS) major parameters objective full-night polysomnography...