A5041805549- Extracellular vesicles in disease
- Autophagy in Disease and Therapy
- Mesenchymal stem cell research
- Soybean genetics and cultivation
- Metabolomics and Mass Spectrometry Studies
- Cancer, Hypoxia, and Metabolism
- Mitochondrial Function and Pathology
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Sirtuins and Resveratrol in Medicine
- Phytase and its Applications
- Sunflower and Safflower Cultivation
- Pomegranate: compositions and health benefits
- Traditional Chinese Medicine Analysis
- Lysosomal Storage Disorders Research
- Calcium signaling and nucleotide metabolism
- Phytoestrogen effects and research
- Sesame and Sesamin Research
- Skin and Cellular Biology Research
- Seed Germination and Physiology
- Plant pathogens and resistance mechanisms
- Plant Ecology and Taxonomy Studies
- Machine Learning and ELM
- Scoliosis diagnosis and treatment
- Cancer-related molecular mechanisms research
Kermanshah University of Medical Sciences
2012-2024
Children's Hospital of Philadelphia
2022-2023
University of California, San Francisco
2023
Mount Sinai Health System
2021
Babol University of Medical Sciences
2020
COVID-19 outbreak has put the whole world in an unprecedented difficult situation bringing life around to a frightening halt and claiming thousands of lives. Due COVID-19's spread 212 countries territories increasing numbers infected cases death tolls mounting 5,212,172 334,915 (as May 22 2020), it remains real threat public health system. This paper renders response combat virus through Artificial Intelligence (AI). Some Deep Learning (DL) methods have been illustrated reach this goal,...
Abstract The current study aimed to investigate the effects of human placental mesenchymal stromal cell‐derived small extracellular vesicles (hPMSC‐sEVs) as a treatment for COVID‐19. This double‐blind, randomized, controlled clinical trial was conducted on two groups patients with COVID‐19‐associated acute respiratory distress syndrome. After randomization, control group received standard and placebo, intervention arm plus hPMSC‐sEVs. number hospital deaths considered primary outcome....
Background: Cancer-associated fibroblasts (CAFs) play an important role in the initiation and progres- sion of tumor cells. These cells can trigger signaling pathways involved progression. HOTAIR, increased long non-coding RNA (lncRNA) breast cancer, has a vital tumorigenesis development cancer Methods: In this study, fibroblast cell culture medium was used to investigate its possible inducing HOTAIR expression PI3K/Akt/mTOR pathway CAFs normal (NFs) were isolated from tumors 6 patients with...
Cancer is among the leading causes of death worldwide and affects a considerable number individuals. Chemotherapy one most common treatment for this condition hair loss prevalent side effects. In study, we report successful patient suffering from persistent chemotherapy-induced alopecia (PCIA) with extracellular enriched vesicles (EVs) derived human placental mesenchymal stromal cells (MSCs).The was 36-year-old woman history invasive ductal carcinoma, underwent six courses chemotherapy...
Autoimmune diseases are caused by an imbalance in the immune system, producing autoantibodies that cause inflammation leading to tissue damage and organ dysfunction. Systemic Lupus Erythematosus (SLE) is one of most common autoimmune a major contributor patient morbidity mortality. Although many drugs manage disease, curative therapy remains elusive, current treatment regimens have substantial side effects. Recently, therapeutic potential exosomes has been extensively studied, novel evidence...
: Background: Staphylococcus aureus is the causative agent of a high percentage nosocomially acquired infections and food-borne illnesses. Antimicrobial resistance S. aureus, especially methicillin-resistant (MRSA), continues to be concernfor clinicians worldwide.Objectives: The aim this study was investigate effects salt stress on antimicrobial drug protein profile aureus.Materials Methods: (ATCC 25823) grown in trypticase soy broth at 37°C. Cells exponential growth phase were gradually...
Allogeneic peripheral blood stem cells transplantation (PBSCT) is now among the treatments for different haematological diseases and malignancies such as acute myeloid leukaemia (AML).1, 2 Although this treatment very advanced, graft-versus-host disease (GVHD) still most common severe side effect.3, 4 Considering time course, GVHD can be divided into two forms: chronic.4, 5 The cumulative incidence of chronic (cGVHD) during first year high 43.8 ± 10% recipients allogeneic marrow...
Although bracing for adolescent idiopathic scoliosis can prevent curve progression and reduce the risk future surgery, children frequently do not wear their braces as prescribed. The purpose of this study is to investigate how a broad array psychosocial characteristics predict compliance with brace wear.This was single institution, prospective cohort study. All adolescents prescribed first-time were eligible. Patients parents completed separate series questionnaires that assessed baseline...
Research has indicated that lower socioeconomic status is associated with delays in the treatment of anterior cruciate ligament (ACL) injuries; however, there a paucity literature evaluating its association patient-reported outcomes (PROs). Using Area Deprivation Index (ADI), validated proxy for status, study aimed to determine how relative disadvantage related PROs after primary ACL reconstruction (ACLR) pediatric patients.This retrospective cohort included all patients 18 years old or...
Background:: Doxorubicin (DOX) is a chemotherapy drug that widely used in cancer therapy, especially Triple-Negative Breast Cancer (TNBC) patients. Nevertheless, cytoprotective autophagy induction by DOX limits its cytotoxic effect and resistance Therefore, finding new way essential for increasing the effectiveness of this treatment. Objective:: This study aimed to investigate L-lysine on cytotoxicity, probably through modulation TNBC cell lines. Methods:: We two lines, MDA-MB-231...
In Brief Mini-abstract: The coronavirus disease 2019 pandemic has presented a unique set of challenges to the field global surgery. this perspective article, authors discuss changes in peri- and post-coronavirus era with anticipated opportunities for patients providers.
Proteomics is a powerful technique to study proteomes extracted from biological sources. Proteome analysis classically based on two-dimensional electrophoresis (2D-E) for protein separation and mass spectrometry (MS) the identification. The serum useful diagnosis that can be used as an indicator of physiological or clinical status patient. One central critical steps sample application, therefore this method should considered optimized 2-DE with immobilized pH gradient. aim was focused...
The pyruvate dehydrogenase complex (PDC) is a multi-enzyme of the mitochondria that provides link between glycolysis and Krebs cycle. PDC plays an essential role in producing acetyl-CoA from glucose regulation fuel consumption. In general, enzyme regulated two different ways, end-product inhibition posttranslational modifications (more extensive phosphorylation dephosphorylation subunit E1). Posttranslational this are by various factors. Sirtuins class III histone deacylatases catalyze...