A5100653546- Computational Drug Discovery Methods
- Food composition and properties
- Heavy Metals in Plants
- Traumatic Brain Injury and Neurovascular Disturbances
- Renal and related cancers
- Cytokine Signaling Pathways and Interactions
- Ginseng Biological Effects and Applications
- Surgical Sutures and Adhesives
- Wound Healing and Treatments
- Inertial Sensor and Navigation
- Berberine and alkaloids research
- Acute Ischemic Stroke Management
- Chronic Kidney Disease and Diabetes
- Phytochemicals and Antioxidant Activities
- Synthesis and biological activity
- Antimicrobial agents and applications
- Selenium in Biological Systems
- SARS-CoV-2 and COVID-19 Research
- Satellite Image Processing and Photogrammetry
- Cannabis and Cannabinoid Research
- Renal Diseases and Glomerulopathies
- Phytoestrogen effects and research
- Cerebrovascular and Carotid Artery Diseases
- Space Satellite Systems and Control
- Protein Kinase Regulation and GTPase Signaling
Second Hospital of Hebei Medical University
2024
Beijing Children’s Hospital
2024
China Aerospace Science and Technology Corporation
2024
Wuhan University of Technology
2024
Hebei Medical University
2024
Chongqing University
2023-2024
Capital Medical University
2024
Shanghai University
2022
Xinxiang Medical University
2018
Zhengzhou University
2014
The natural compound berberine has been reported to exhibit anti-diabetic activity and improve disordered lipid metabolism. In our previous study, we found that such compounds upregulate expression of sirtuin 1—a key molecule in caloric restriction, it is, therefore, great interest examine the lipid-lowering combination with a 1 activator resveratrol. Our results showed resveratrol had enhanced hypolipidemic effects high fat diet-induced mice was able decrease accumulation adipocytes level...
Under the selective pressure of nirmatrelvir, a peptidomimetic covalent drug targeting SARS-CoV-2 Mpro, various drug-resistant mutations on Mpro have been acquired in vitro. Among mutations, L50F and E166V, along with combination are particularly representative pose considerable obstacles to effective treatment COVID-19. Our previous study identified NMI-001 NMI-002 as novel nonpeptide inhibitors that target possessing unique scaffolds binding modes different from those nirmatrelvir. In view...
Background and objectiveCerebral edema (CED) is a serious complication of acute ischemic stroke (AIS), especially in patients with large hemispheric infarction (LHI). Herein, deep learning-based approach implemented to extract CSF from T2-Weighted Imaging (T2WI) evaluate the relationship between quantified cerebrospinal fluid outcomes.Methods.Patients LHI who underwent magnetic resonance imaging (MRI)were included. We used learning algorithm segment T2WI. The ratio was calculated its degree...
Achieving underwater adhesion possesses a significant challenge, primarily due to the presence of interfacial water, which restricts potential applications adhesives. In this study, we present straightforward and environmentally friendly one-pot approach for synthesizing solvent-free supramolecular TPFe bioadhesive composed thioctic acid, proanthocyanidins, FeCl3. The exhibits excellent biocompatibility photothermal antibacterial properties demonstrates effective on various substrates in...
This paper studies the inherent image motion, solely introduced by orbital motion and Earth’s rotation during along-track dynamic TDI imaging, based upon assumption that ideal attitude compensation is achieved, perfect satellite platform employed. After being classified into angle-rotation, size-scaling, Earth-rotation motions, characteristics of are systematically analyzed. To best our knowledge, size-scaling discussed for first time, which has never been noticed traditional imaging but...
Abstract Background Proteinuria is a prevalent symptom of pediatric nephrology, while kidney biopsy remains the gold standard for tissue analysis, and it currently controversial. We report rare case that mutation in AMN gene was considered to cause chronically isolated proteinuria also suggest renal should be chosen with caution children chronic non-nephrotic levels genetic testing may feasible early precise diagnosis. Case presentation A 35-month-old boy presented excessive urine foaming...
Abstract Background and Objective Biofortification with inorganic selenium has become a key strategy to enhance content in crops. This study aimed investigate the changes of phenolic compounds their effects on antimicrobial antioxidant activities during vitro digestion biofortified germinated black soybeans (GBS‐Se). Findings The bioaccessibility total polyphenols flavonoids GBS‐Se were significantly lower than those (GBS). p ‐Coumaric acid salicylic GBS increased oral phase; syringic...