A5005003245- Advanced biosensing and bioanalysis techniques
- Nanoparticles: synthesis and applications
- Silk-based biomaterials and applications
- Food composition and properties
- Pulmonary Hypertension Research and Treatments
- Phytochemicals and Antioxidant Activities
- Biosensors and Analytical Detection
- Graphene and Nanomaterials Applications
- Proteins in Food Systems
- RNA Interference and Gene Delivery
- Advanced Sensor and Energy Harvesting Materials
- Phytoestrogen effects and research
- Plant Virus Research Studies
- Electrochemical Analysis and Applications
- Bacteriophages and microbial interactions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Conducting polymers and applications
- Electrospun Nanofibers in Biomedical Applications
- Phytase and its Applications
- Heavy Metals in Plants
- Carbon and Quantum Dots Applications
- Essential Oils and Antimicrobial Activity
- Air Quality and Health Impacts
- Antioxidant Activity and Oxidative Stress
- Antibiotics Pharmacokinetics and Efficacy
Shanghai University
2016-2025
Ocean University of China
2025
Nantong University
2025
Guangzhou Medical University
2016-2019
First Affiliated Hospital of Guangzhou Medical University
2016-2019
State Key Laboratory of Respiratory Disease
2016-2019
Johns Hopkins Medicine
2016
Johns Hopkins University
2016
Geisinger Medical Center
2016
Yunnan Agricultural University
2016
Developing efficient therapeutic strategies for combating bacterial infection remains a challenge owing to the indiscriminate utilization of antibiotics and prevalence multidrug-resistant (MDR) bacteria. Herein, highly graphitic-N-doped graphene quantum dots (N-GQDs) with NIR-II photothermal conversion properties were synthesized first time antibacterial therapy. The obtained N-GQDs exhibited strong NIR absorption ranging from 700 1200 nm, achieving high efficiency 77.8% 50.4% at 808 1064...
Animal model of cigarette smoke (CS) -induced chronic obstructive pulmonary disease (COPD) is the primary testing methodology for drug therapies and studies on pathogenic mechanisms disease. However, researchers have rarely run simultaneous or side-by-side tests whole-body nose-only CS exposure in building their mouse models COPD. We compared evaluated these two different methods exposure, plus airway Lipopolysaccharides (LPS) inhalation, our COPD model. Compared with control group, exposed...
This study evaluated the volatile organic compounds (VOCs) and taste properties of Gorgon Euryale seeds processed by five methods (steaming, boiling, microwaving, roasting, stir-frying) using electronic tongue (E-tongue), nose (E-nose), gas chromatography-mass spectrometry (GC-MS), chromatography-ion mobility (GC-IMS). A total 44 40 VOCs were identified GC-MS GC-IMS, respectively. Pyrazines (2-ethyl-3,5-dimethylpyrazine, 2,3-diethyl-5-methylpyrazine) furans (2-pentylfuran, 2-ethylfuran)...
ABSTRACT Multidrug-resistant Escherichia coli poses a significant threat to the healthcare system by causing treatment failure in infected patients. The use of beta-lactam combination with beta-lactamase inhibitor has been shown be an effective strategy solve this problem. In vitro antimicrobial susceptibility experiments have demonstrated activity aztreonam and clavulanate. investigation, we conducted transcriptomic analysis reveal downstream differential gene expression E. ymmD45 (a strain...
Acute kidney injury (AKI) is a common side effect of acetaminophen (APAP) overdose. Dihydromyricetin (DHM) the most abundant flavonoid in rattan tea, which has wide range pharmacological effects. In current study, APAP-induced AKI models were established both vivo and vitro. The results showed that DHM pretreatment remarkably alleviated by promoting antioxidant capacity through nuclear factor erythroid-related 2 (Nrf2) signaling pathway vivo. addition, reduced ROS production mitochondrial...
The interaction between three flavonoids, i.e., Luteolin (LTL), Quercetin (QCT), and Naringenin (NGN) bovine lactoferrin (BLF) at pH 7.4 was investigated by fluorescence quenching spectra, synchronous UV-visible absorption spectra. results indicate the of BLF quenched via static quenching. main force QCT LTL with van der Waals interactions hydrogen bonds. Electrostatic played a major role in binding process NGN BLF. Synchronous used to study conformational changes values constant (Ka) number...
A transparent, conductive, smooth, and temperature sensitive thin films was fabricated characterized in this paper. Silk fibroin could be processed into transparent films, which can act as ideal opto-electronic substrates. As pure silk film is nonconductive, ultra-long silver nanowires coating platinum sputtering were used to strengthen its conductivity. Ultra-long reduce the junctions between wires, improve conductivity of film. The new nanowire-metal-organic composite possesses excellent...
Biofortification using inorganic selenium has become an effective strategy to enhance content in crops. In the present study, effects of biofortification on chemical composition and antioxidant capacity black soybean (BS) during germination were studied. The contents selenium, total sugar, vitamin C, γ-aminobutyric acid, polyphenols, flavonoids biofortified germinated soybeans (GBS-Se) significantly increased compared (GBS). However, soluble protein, fat, reducing sugar decreased, while...
Background: Chronic respiratory disease-associated pulmonary hypertension (PH) is an important subtype of PH, which lacks clinical epidemiological data in China. Methods: Six hundred and ninety three patients hospitalized from 2010 to 2013 were classified by echocardiography according arterial systolic pressure (PASP): mild (36≤ PASP <50 mmHg); moderate (50≤ <70 mmHg) severe (PASP ≥70 mmHg). Results: Dyspnea (93.51%) was the most common symptom. Hemoptysis observed group (6.42%)...
For decades, stem cell therapies for pulmonary hypertension (PH) have progressed from laboratory hypothesis to clinical practice. Promising preclinical investigations laid both a theoretical and practical foundation application of mesenchymal cells (MSCs) PH therapy. However, the underlying mechanisms are still poorly understood. We sought study effects MSCs on treatment PH.