A5052673051- Polysaccharides and Plant Cell Walls
- Microbial Metabolites in Food Biotechnology
- Polysaccharides Composition and Applications
- Proteins in Food Systems
- Phytochemistry and Bioactive Compounds
- Parasitic Infections and Diagnostics
- Phytochemicals and Antioxidant Activities
- Sesquiterpenes and Asteraceae Studies
- Plant biochemistry and biosynthesis
- Fungal Biology and Applications
- Cancer Cells and Metastasis
- Parasitic infections in humans and animals
- Natural Compound Pharmacology Studies
- Plant Surface Properties and Treatments
- Seaweed-derived Bioactive Compounds
- Bee Products Chemical Analysis
- Cynara cardunculus studies
- Tea Polyphenols and Effects
- Natural Antidiabetic Agents Studies
Universidade Federal do Paraná
2019-2023
Chamomile is one of the most ancient medicinal herbs known to mankind and among its traditional uses are calming effects. However, few studies explored effects on central nervous system (CNS). In this study we further proceed with structural elucidation polysaccharides from chamomile tea. A highly substituted 4-O-methyl-glucuronoxylan (fraction SN-50R) was purified chemically characterized, presenting Xyl:GlcA ratio 1.7:1, Mw 500 kDa total sugar content 98%. Its bioactivity pain CNS...
Chamomile is one of most known species medicinal plants. It has valuable pharmacological properties that produce positive effects in many therapeutical uses. Some these are attributed to the presence secondary metabolites but already primary can also effects. In this study we elucidate fine chemical structure polysaccharides present infusion chamomile flower chapters. After ethanolic precipitation, were obtained from tea (fraction MRW, 3.2% yield), purified and characterized as an inulin...
This study investigated the antineoplastic effects and toxicity of long-term treatment with polysaccharides from sweet green pepper (Capsicum annuum [CAP]), concomitant CAP + methotrexate (MTX) on mammary tumor cells in vivo vitro. Ehrlich were subcutaneously inoculated female Swiss mice. The (31 days) (100 mg kg−1, p.o.) reduced growth did not induce toxicity. combined protocol 100 kg−1 (p.o.) 1 MTX (i.p.) for 21 days inhibited 95%, higher than inhibition induced by alone (1.0 or 2.5 i.p.)....
Baccharis trimera is a native medicinal plant from South America popularly known as "carqueja". Its infusion traditionally ingested for the treatment and prevention of hepatic disorders. Up to now, only crude aqueous extract or hydroethanolic fractions, containing secondary metabolites, have been studied correlated with their biological action on liver. Here we report that an inulin type fructan present in B. contributes hepatoprotective effect species. In vitro, at 300 μg/mL, was able...
Mannans has been attracted the interest in various sectors due to its promising applications. The low toxicity of mannans allows for their use cosmetics, pharmaceutical, and biomedical industries. In this study, α-D-mannan extraction conditions from Aureobasidium pullulans by alkaline were optimized using a Box-Behnken design (BBD). effect temperature (°C), pH time (hours) on yield α-mannan was investigated. that produced highest (26%) 92 °C, 3 h 13. addition, structure confirmed methylation...
Giardia intestinalis (syn. G. lamblia, duodenalis) is a protozoa parasite that produces one of the most frequent waterborne causes diarrhea worldwide. This protozoan infects mammals, including humans, and colonizes small intestine, adhering to intestinal cells. The mechanism by which multifactorial, causing malabsorption. treatment giardiasis uses chemotherapeutic drugs such as nitroimidazoles, furazolidone, paromomycin, benzimidazole compounds. However, they are toxic, refractory, may...