A5033330705- Hearing, Cochlea, Tinnitus, Genetics
- Ear Surgery and Otitis Media
- Sinusitis and nasal conditions
- Vestibular and auditory disorders
- Head and Neck Surgical Oncology
- Oral and Maxillofacial Pathology
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Bone Tumor Diagnosis and Treatments
- Obstructive Sleep Apnea Research
- Nasal Surgery and Airway Studies
- Ear and Head Tumors
- Glaucoma and retinal disorders
- Voice and Speech Disorders
- Noise Effects and Management
- Allergic Rhinitis and Sensitization
- Vaccine Coverage and Hesitancy
- Infections and bacterial resistance
- Cervical Cancer and HPV Research
- Salivary Gland Tumors Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Axon Guidance and Neuronal Signaling
- Tumors and Oncological Cases
- Neonatal Respiratory Health Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
University of Palermo
2021-2025
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2021-2024
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by a type 2 pattern of inflammation. Mepolizumab was approved for the treatment CRSwNP in 2021. However, there lack real-life studies. This work aimed to evaluate effectiveness and safety profile during first year setting. A multicentric observational cohort study carried out. total 67 patients were enrolled Otorhinolaryngology Unit three University Hospitals considered therapy. All recorder characteristics age (at...
This study aimed to evaluate the effectiveness and safety of dupilumab during first year treatment in a real-life setting, focusing on improvement nasal polyp score (NPS) as well specific symptoms, quality life olfactory function.A multicentric observational cohort was carried out. A total 170 patients were enrolled Otorhinolaryngology Unit three University Hospitals considered for therapy. All recorder characteristics age (at application visit), sex, smoke habits, previous local systemic...
Objectives: The aim of this study is to analyze the correlation between nasal anatomical variants and clinical radiological features odontogenic sinusitis demonstrate their possible involvement in genesis disease. Methods: This a retrospective multicentric 70 patients with (OS). Before surgery, all performed classic mini 22-item Sino-Nasal Outcome Test (SNOT-22 SNOT-8) Lund–Mackay Score (LMS). Each anomaly was collected, including paradoxical middle turbinate (PMT), chonca bullosa (CB),...
Tumours of the nasal septum are a rare and heterogeneous group lesions in sinonasal tract. The management different this site is debated. aim study to share our experience on clinical condition stimulate other centres publish theirs.We retrospectively analysed databases tumours treated at Sections Otolaryngology (ENT) two University Hospitals (Palermo Genova) between 2012 2020.From databases, cohort 32 patients with were selected. All underwent an endoscopic examination. Large preoperative...
To date, histological biomarkers expressed by laryngeal cancer are poorly known. The identification of associated with squamous cell carcinoma (SCC), would help explain the tumorogenesis and prevent possible recurrence lesion after treatment. For this reason, aim study is to investigate, for first time, Orphanin expression in 48 human specimens SCC evaluate its correlation patients prognosis. We analyzed pathological from detect presence using an immunohistochemistry test. compared findings...
Since the introduction of Highly Active Anti-Retroviral Therapy (HAART), there has been a significant increase in survival HIV-infected patients. Consequently, increased attention on potential neoplastic pathologies, such as Kaposi's sarcoma, associated with AIDS these individuals.
ChatGPT is an advanced language model developed by OpenAI, designed for natural understanding and generation. It employs deep learning technology to comprehend generate human-like text, making it versatile various applications. The aim of this study assess the alignment between Rhinology Board’s indications ChatGPT’s recommendations treating patients with chronic rhinosinusitis nasal polyps (CRSwNP) using biologic therapy. An observational cohort involving 72 was conducted evaluate...
Background: Newborns admitted to neonatal intensive care units (NICUs) are at higher risk of developing sensorineural hearing loss (SNHL), which may improve over time. The aim this study was describe the prevalence main factors for SNHL in a NICU cohort, focusing on children who underwent auditory maturation. Methods: An observational 378 NICUs, were followed least 18 months, with periodic audiologic assessments. Results: Out patients, 338 had normal and 40 hearing-impaired; we found...
Objective. This study reports our experience in a selected cohort of patients affected by mild-moderate OSAS, without tonsillar obstruction, and treated with pharyngoplasty. Methods. In case-control retrospective study, we compared modified expansion sphincter pharyngoplasty (MESP) to barbed reposition (MBRP) adult oropharyngeal transversal collapse BMI ≤ 30 kg/m2, obstructive sleep apnoea syndrome (OSAS). A clinical evaluation, including collection anthropometric data endoscopy, was...
Reporting our experience in treating chronic obstructive sialadenitis with a protocol consisting of sialoendoscopy and intraductal instillation antibiotics, steroids n-acetyl-cysteine (NAC) solution.Prospective study patients no apparent lithiasic obstructions, recurrent non-lithiasic sialoadenitis not solved sialoendoscopy. In all cases, was performed. All the affected by where inflammation resolved were excluded from study. The mid-term follow-up performed at 12 months via phone interview,...
Pneumolabyrinth is a condition characterised by the presence of air within inner ear and rare complication after cochlear implant surgery. One causes pneumolabyrinth may be increase in pressure middle ear. The use continuous positive airway (CPAP) an effective treatment strategy for obstructive sleep apnoea. According to recent study, CPAP should delayed 1 or 2 weeks subjects undergoing surgery; however, there currently no indication delay We report case patient on who underwent left...
Solitary fibrous tumor (SFT) is a rare mesenchymal that usually arises from the pleura but can also occur in extrapleural sites, such as sinonasal region. It causes aspecific symptoms, including nasal obstruction and discharge, postnasal drip, anosmia, epistaxis, headache. may be difficult to distinguish these symptoms those caused by other lesions this site, especially when tissues undergo iatrogenic damage following surgical removal.This case report shows right septal solitary tumor, which...
Noise-induced hearing loss (NIHL) is defined as the sensorineural caused by acute acoustic trauma or chronic exposure to high-intensity noises. Exposure noises can lead irreversible damage inner ear and, consequently, a permanent shift of threshold. Police officers are particularly at risk damages. The aim this study evaluate police in relation occupational factors and clinical-anamnestic characteristics collecting analyzing existing data evidence available public databases.A systematic...
Migraine vertigo (MV) and Ménière's disease (MD) share several signs symptoms such as tinnitus, fullness, photophobia, phonophobia, headache spells lasting hours.The aim of the present study was to prospectively observe patients with MV a sporadic audiological symptom evaluated clinical examination, Vestibular Evoked Myogenic Potentials (VEMPs), ECochG v-HIT.The finding VEMP asymmetry, according our cut-off 33% difference between sides, resulted in 20 cases, which 6 had asymmetry both...
Background: this prospective study investigated the correlation between oral bacterial microflora and found in voice prostheses (VPs) among 20 patients who had undergone laryngectomy. The aim was to explore associations microflora’s presence malfunction of VPs, along with association predominant microorganism longevity VPs. Methods: research process included gathering medical histories, conducting ENT examinations, replacing performing check-ups every four months for a period 15.5 months....
Nasal and paranasal sinus masses can arise from a wide range of conditions, both benign malignant, as well congenital or acquired. Diagnosing these is often challenging, requiring combination nasal endoscopy, imaging studies, histopathological analysis. Initial frequently involves computed tomography cone beam (CBCT) to evaluate the bony anatomy cavity surrounding sinuses, while magnetic resonance (MRI) typically used for detailed assessment soft tissues aid in differential diagnosis when...
Objectives To evaluate the diagnostic role of combined electrocochleography and pure-tone audiometry monitoring during dehydrating test in Ménière's disease consider its suitability as a tool to differentiate those patients with unclear differential diagnosis therefore identify clear endolymphatic hydrops responsive test. study efficacy therapy on vertiginous symptoms hearing loss disease. Study Design Prospective case series. Settings University hospital, secondary referral center. Patients...