A5018210613- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Dengue and Mosquito Control Research
- Malaria Research and Control
- Insect symbiosis and bacterial influences
- COVID-19 epidemiological studies
- Insect Pest Control Strategies
- Insect and Pesticide Research
- T-cell and Retrovirus Studies
- Virology and Viral Diseases
- Animal Disease Management and Epidemiology
- Public Health and Social Inequalities
- HIV/AIDS oral health manifestations
- HIV, Drug Use, Sexual Risk
- SARS-CoV-2 and COVID-19 Research
- Insects and Parasite Interactions
- Diabetic Foot Ulcer Assessment and Management
- HIV/AIDS Research and Interventions
- Herpesvirus Infections and Treatments
- Dermatological diseases and infestations
- Forest Insect Ecology and Management
- Vector-Borne Animal Diseases
- Trypanosoma species research and implications
- Sexual function and dysfunction studies
- Food Security and Health in Diverse Populations
Autonomous University of Yucatán
2012-2025
Management Support Technology (United States)
2019
Emory University
2019
Background The combination of Wolbachia -based incompatible insect technique (IIT) and radiation-based sterile (SIT) can be used for population suppression Aedes aegypti . Our main objective was to evaluate whether open-field mass-releases w AlbB-infected Ae males, as part an Integrated Vector Management (IVM) plan led by the Mexican Ministry Health, could suppress natural populations in urbanized settings south Mexico. Methodology/Principal findings We implemented a controlled...
Response to Zika virus (ZIKV) invasion in Brazil lagged a year from its estimated February 2014 introduction, and was triggered by the occurrence of severe congenital malformations. Dengue (DENV) chikungunya (CHIKV) invasions tend show similar response lags. We analyzed geo-coded symptomatic case reports city Merida, Mexico, with goal assessing utility historical DENV data infer CHIKV ZIKV introduction propagation. About 42% 40,028 cases reported during 2008–2015 clustered 27% city, these...
The socioecological conditions of Mexican regions are conducive to the spread vector-borne diseases. Although there established treatment guidelines for dengue and rickettsiosis, diagnosis is complicated. objective this work was identify epitopes Rickettsia virus that could be used in serology screening against For this, with high histocompatibility complex class II binding efficiency OmpB protein rickettsii NS2B were identified silico through a reverse vaccinology strategy. selected grouped...
Background In the absence of vaccines or drugs, insecticides are mainstay Aedes -borne disease control. Their utility is challenged by slow deployment resources, poor community compliance and inadequate household coverage. Novel application methods required. Methodology principal findings A 10% w/w metofluthrin “emanator” that passively disseminates insecticide from an impregnated net was evaluated in a randomized trial 200 houses Mexico. The devices were introduced at rate 1 per room...
Abstract Background Current urban vector control strategies have failed to contain dengue epidemics and prevent the global expansion of Aedes -borne viruses (ABVs: dengue, chikungunya, Zika). Part challenge in sustaining effective ABV emerges from paucity evidence regarding epidemiological impact any method. A strategy for which there is limited targeted indoor residual spraying (TIRS). TIRS a modification classic malaria that accounts aegypti resting behavior by applying insecticides on...
We conducted an analytical cross-sectional survey to estimate the prevalence of and factors associated with active head lice infestation. In total 140 children, aged 6 16-years, from a public school in rural Yucatan, Mexico, were examined by wet-combing. A structured questionnaire was used collect information on individuals conditions surrounding environment. Head infestation found 19 out children tested (13.6%) this both lower income (OR 9.9, 95% CI 2.15-45.79, p = 0.003) higher frequency...
Quantification of adult Aedes aegypti abundance indoors has relied on estimates relative density (e.g. number adults per unit sampling or time), most commonly using traps timed collections aspirators. The lack the sensitivity and a numerical association between absolute Ae. represent significant gap in vector surveillance. Here, we describe use sequential removal to estimate numbers indoor resting calculate calibration coefficients for Prokopack aspirator city Merida, Yucatan State, Mexico....
Dengue is the most prevalent mosquito-borne viral disease of humans and caused by four serotypes dengue virus. To estimate incidence other arboviruses, we analyzed baseline first year follow-up a prospective school-based cohort study their families in three cities state Yucatan, Mexico. Through enhanced surveillance activities, acute febrile illnesses participants were detected yearly blood samples collected to evaluate infection incidence. A Cox model was fitted identify hazard ratios...
We conducted a baseline characterization of the abundance and seasonality Aedes aegypti (Linnaeus, 1762)-a vector dengue, chikungunya, Zika-in two suburban localities Yucatan, Mexico, as first step in implementation an integrated management (IVM) plan combining 'traditional control' (source reduction/truck-mounted ultra-low volume [ULV] spraying) incompatible insect technique/sterile technique for population suppression Mexico. Weekly entomological collections with ovitraps BG-sentinel traps...
Arbovirus infection in Aedes aegypti has historically been quantified from a sample of the adult population by pooling collected mosquitoes to increase detectability. However, there is significant knowledge gap about magnitude natural arbovirus within areas active transmission, as well sensitivity detection such an approach. We used indoor Ae. sequential sampling with Prokopack aspirators collect all inside 200 houses suspected ABV transmission city Mérida, Mexico, and tested specimens...
Background The integration of house-screening and long-lasting insecticidal nets, known as insecticide-treated screening (ITS), can provide simple, safe, low-tech Aedes aegypti control. Cluster randomised controlled trials in two endemic localities for Ae . south Mexico, showed that ITS conferred both, immediate sustained (~2 yr) impact on indoor-female infestations. Such encouraging results require further validation with studies quantifying more epidemiologically-related endpoints,...
Abstract Insecticide-based approaches remain a key pillar for Aedes -borne virus (ABV, dengue, chikungunya, Zika) control, yet they are challenged by the limited effect of traditional outdoor insecticide campaigns responding to reported arboviral cases and emergence resistance in mosquitoes. A three-arm Phase II unblinded entomological cluster randomized trial was conducted Merida, Yucatan State, Mexico, quantify impact targeted indoor residual spraying (TIRS, application insecticides Ae....
ABSTRACT. Since the Zika virus (ZIKV) pandemic in 2015–2017, there has been a near absence of reported cases Americas outside Brazil. However, conditions for Aedes -borne transmission persist Latin America, and threat ZIKV is increasing as population immunity wanes. Mexico only 70 laboratory-confirmed infection since 2020, with no recorded Yucatán peninsula. Here, we provide evidence active transmission, despite official case reports, city Mérida, Mexico, capital state Yucatán. Capitalizing...
ABSTRACT We evaluated a commercially available immunochromatographic dipstick test to detect Trypanosoma cruzi infection in 366 human serum samples with known serological results from Argentina, Ecuador, Mexico, and Venezuela. One hundred forty-nine of (40.7%) 171/366 (46.7%) tested positive by serology, respectively. Dipstick sensitivity was calculated be 84.8% (range between countries, 77.5 95%), specificity 97.9% (95.9 100%).
Dengue transmission in Mexico has become a major public health problem. Few epidemiological studies have examined the seroprevalence of dengue Mexico, and recent estimates are needed to better understand dynamics. We conducted survey among 1,668 individuals including all age groups three urban settings Yucatan, Mexico. Children (< 19 years old) were selected randomly from schools. The adults (≥ healthcare facilities. Participants asked provide venous blood sample answer brief questionnaire...
Background The implementation of vector control interventions and potential introduction new tools requires baseline data to evaluate their direct indirect effects. objective the study is present seroprevalence dengue infection in a cohort children 0 15 years old followed during 2015 2016, risk factors role enhanced surveillance strategies three urban sites (Merida, Ticul Progreso) Yucatan, Mexico. Methods A school family members was randomly selected areas with different demographic, social...
We report demographic, epidemiologic, and clinical findings for a prospective cohort of pregnant women during the initial phase Zika virus introduction into Yucatan, Mexico. monitored 115 signs active or recent infection. The estimated cumulative incidence infection was 0.31 ratio symptomatic to asymptomatic cases 1.7 (range 1.3-4.0 depending on age group). Exanthema most sensitive sign but also least specific. Conjunctival hyperemia, joint edema, exanthema were combination that had highest...
To evaluate the protective effect of house screening (HS) on indoor Aedes aegypti infestation, abundance and arboviral infection in Merida, Mexico.In 2019, we performed a cluster randomised controlled trial (6 control 6 intervention areas: 100 households/area). Intervention clusters received permanently fixed fiberglass HS all windows doors. The study included two cross-sectional entomologic surveys, one baseline (dry season May 2019) post-intervention (PI, rainy between September October...
Fitting long-lasting insecticidal nets (LLIN) as screens on doors/windows has a significant impact indoor-adult Aedes aegypti (L.), with entomological reductions measured in previous study being for up to 2 yr post-installation, even the presence of pyrethroid-resistant populations. To better understand mode LLIN protection, bioassays were performed evaluate effects field deployment (0, 6, and 12 mo) damage type (none, central, lateral, multiple) efficacy. Contact confirmed that residual...
El loxoscelismo es ocasionado cuando el veneno dermonecrótico producido por las arañas del género Loxosceles, conocidas como “arañas violinistas”, ingresa al organismo de una persona a través su mordida. En México ocurre un subregistro los casos la ausencia pruebas laboratorio para diagnóstico y dificultad cuadro clínico. objetivo este trabajo describir caso cutáneo mordedura Loxosceles yucatana en residente Yucatán, México. tipo más frecuente menos severo. presente se diagnosticó medio...