A5048995685- Cardiac electrophysiology and arrhythmias
- Acute Ischemic Stroke Management
- Lymphoma Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Trauma and Emergency Care Studies
- Neuroscience and Neural Engineering
- Cardiac pacing and defibrillation studies
- Electrospun Nanofibers in Biomedical Applications
- Anatomy and Medical Technology
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cell Adhesion Molecules Research
- Parathyroid Disorders and Treatments
- Radiopharmaceutical Chemistry and Applications
- Surgical Sutures and Adhesives
- Atrial Fibrillation Management and Outcomes
- 3D Printing in Biomedical Research
- Medical Imaging and Pathology Studies
- Cardiac Arrhythmias and Treatments
- Additive Manufacturing and 3D Printing Technologies
- Graphene and Nanomaterials Applications
- Venous Thromboembolism Diagnosis and Management
- Wound Healing and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Blood transfusion and management
- Cellular Mechanics and Interactions
University of Pittsburgh Medical Center
2024
University of Pittsburgh
2024
The University of Texas at Austin
2020-2023
Houston Institute for Clinical Research
2021
Abstract A major challenge in chronic wound treatment is maintaining an appropriate moisture balance throughout the healing process. Wound dehydration hinders due to impeded molecule transport and cell migration with associated tissue necrosis. In contrast, wounds that produce excess fluid contain high levels of reactive oxygen species matrix metalloproteases impede recruitment, extracellular reconstruction, angiogenesis. Dressings are currently selected based on relative amount exudate no...
INTRODUCTION Traumatic brain injury (TBI) patients on antiplatelet therapy face higher mortality because of impaired platelet function, which may be treated by transfusion. The value testing function in this cohort remains controversial. We aimed to evaluate the relationship between assays and outcomes TBI receiving transfusions. hypothesized that magnitude change assay performance following a transfusion would predict meaningful clinical outcomes. METHODS A patients, aged 18 89 years, with...
Few studies have examined heat transfer and thermal injury on the epiesophageal surface during radiofrequency application, or compared risk of esophageal between standard high-power, short-duration (HPSD) ablation. We studied thermodynamics HPSD ablation at different tissue interfaces left atrium esophagus, focusing temperature changes injury.Fresh porcine heart sections were secured to a custom holder submerged in temperature-controlled, circulating water bath. During ablation, thermistors...
Trauma is the leading cause of death in individuals up to 45 years age. Alterations platelet function are a critical component trauma-induced coagulopathy (TIC), yet these changes and potential resulting dysfunction incompletely understood. The lack clinical assays available explore this patient population has hindered detailed understanding role platelets TIC. objective study was assess trauma ex vivo flow-dependent hemostatic capacity microfluidic model. We hypothesized that patients would...
Background: The impact of left ventricular systolic dysfunction on survival and hospitalizations in patients with transthyretin cardiomyopathy (ATTR-CM) remains underexplored. Methods: Patients confirmed ATTR-CM were categorized into HFrEF (LVEF < 50%) HFpEF ≥ groups. Regression models identified predictors reduced ejection fraction. Kaplan-Meier analysis, multivariable Cox proportional hazards models, time-varying used to assess heart failure (HF) hospitalization rates. Results: 132...