A5016179380- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Nitric Oxide and Endothelin Effects
- Eicosanoids and Hypertension Pharmacology
- Psychedelics and Drug Studies
- Historical and socio-economic studies of Spain and related regions
- Nicotinic Acetylcholine Receptors Study
- Public Health and Social Inequalities
- Urbanism, Landscape, and Tourism Studies
- Health, Education, and Physical Culture
- Cardiac Ischemia and Reperfusion
- Biomedical Ethics and Regulation
- Neuropeptides and Animal Physiology
- Advertising and Communication Studies
- Tryptophan and brain disorders
- Forensic Toxicology and Drug Analysis
- Smoking Behavior and Cessation
- Electron Spin Resonance Studies
- Environmental and sustainability education
- Finance, Taxation, and Governance
- Latin American Cultural Politics
- Communication and COVID-19 Impact
- Journalism and Media Studies
- Migraine and Headache Studies
- Sleep and Wakefulness Research
Universidad Nacional de Córdoba
2018-2024
Consejo Nacional de Investigaciones Científicas y Técnicas
1999-2007
Universitat Pompeu Fabra
2003-2005
University of Buenos Aires
1998
It has been shown previously that the endogenous opioid system may be involved in behavioral effects of nicotine. In present study, participation enkephalins on nicotine responses investigated by using preproenkephalin knock-out mice. Acute nicotine-induced hypolocomotion remained unaffected these contrast, antinociception elicited tail-immersion and hot-plate tests acute administration was reduced mutant animals. The rewarding properties were then place-conditioning paradigm. Nicotine...
In addition to their classical known effects, such as analgesia, impairment of cognition and learning appetite enhancement, cannabinoids have also been related the regulation cardiovascular responses implicated in pathology. Elevated levels endocannabinoids extreme hypotension associated with various forms shock well abnormalities that accompany cirrhosis. contrast, beneficial effects on system, a protective role atherosclerosis progression cerebral myocardial ischaemia. addition, it has...
To assess the involvement of endothelial α 2 ‐adrenoceptors in clonidine‐induced vasodilatation, mesenteric artery Sprague Dawley rats was cannulated and perfused with Tyrode solution (2 ml min −1 ). We measured perfusion pressure, nitric oxide (NO) perfusate using chemiluminescence, tissue cyclic GMP by RIA. In phenylephrine‐precontracted mesenteries, clonidine elicited concentration‐dependent vasodilatations associated to a rise luminal NO. One hundred n M rauwolscine or 100 μ L ω ‐nitro‐...
Numerous studies have shown the existence of functional links between endogenous cannabinoid and opioid systems. However, extensive research is still needed to elucidate biochemical mechanisms involved in this cannabinoid-opioid interaction. Mice lacking mu- (MOR), delta- (DOR) kappa- (KOR) receptors been generated some specific pharmacological effects induced by cannabinoids reported be modified these animals. In order clarify further possible modification responses we now evaluated...
Abstract The involvement of µ‐opioid receptors in the rewarding properties MDMA was explored receptor knockout mice using conditioning place preference paradigm. associated release dopamine nucleus accumbens investigated by vivo microdialysis. A significant effect (10 mg/kg, i.p.) observed both wild‐type and mice. also induced similar increases decreases 3,4‐dihydroxyphenylacetic acid homovanillic dialysates No differences basal levels dopamine, or acids between were observed. In summary,...
La pandemia de COVID-19 generó una crisis mundial que puso en tensión distintos planos la existencia humana. En el plano salud, modelo biomédico hegemónico imperó los modos explicar y ofrecer soluciones; sin embargo, su mirada biologicista resultó insuficiente, lo cual habilitó preguntas reflexiones sobre dimensión sociohistórica situada cuerpos tela juicio las formas producción capitalista sus vínculos con viviente. este artículo se realiza revisión crítica del para, luego, dialogar desde...
The classical notion of science as being neutral and devoid responsibilities for the problematic consequences results scientific research has been progressively eroded. In this new context, scientists are compelled to go outside their traditional refuge, lab, render account society, systematically. present paper analyzes context in which these transformations have occurred most recent history. Moreover, it reflects about reasons why organizations begun promote idea that communicating general...
1 The effects of the chronic in vivo inhibition nitric oxide synthase (NOS) with N ω ‐nitro‐ l ‐arginine methyl ester (L‐NAME) on vascular contractility were studied rat perfused mesenteric bed. treatment L‐NAME during 4 weeks induced a rise systolic blood pressure (basal: 115.1 ± 6.5 mmHg; treatment: 171.7 7.7 mmHg, n = 16, P < 0.05). 2 After NOS inhibition, potentiation maximal vasoconstrictor responses to noradrenaline, phenylephrine and KCl was same extent as that observed after vitro...
En este artículo nos proponemos visibilizar las tramas de comunicación en salud que persisten atadas a un modelo biomédico hegemónico y cuya pretensión universalidad dificulta la creación manifestación concepciones una manera integral situada. A partir abordaje reflexivo, intentaremos contribuir con propuestas divergentes los enfoques vinculados divulgación contenidos científicos técnicos como mera operación “traducción”, para repensar posibilidades articular sensible trama socio-cultural,...
1Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain 2Laboratory of Molecular Neurobiology, Department Psychiatry, University Bonn, 53105 Germany E-mail: [email protected] Abstracts the 11th Biennial EBPS Meeting