A5036017941- Per- and polyfluoroalkyl substances research
- Bioinformatics and Genomic Networks
- Birth, Development, and Health
- Metabolomics and Mass Spectrometry Studies
- Health, Environment, Cognitive Aging
- Pharmaceutical and Antibiotic Environmental Impacts
- Effects and risks of endocrine disrupting chemicals
- Neonatal Respiratory Health Research
- Heavy Metal Exposure and Toxicity
- Pregnancy and preeclampsia studies
- Ovarian function and disorders
- Atmospheric chemistry and aerosols
- Gestational Diabetes Research and Management
- Pesticide and Herbicide Environmental Studies
- Preterm Birth and Chorioamnionitis
Peking University
2022-2024
National Health and Family Planning Commission
2022-2024
Permeabilities of various trace elements (TEs) through the blood–follicle barrier (BFB) play an important role in oocyte development. However, it has not been comprehensively described as well its involved biological pathways. Our study aimed to construct a distribution model concerned TEs and explore their related We finally included total 168 women from cohort vitro fertilization-embryo transfer conducted two reproductive centers Beijing City Shandong Province, China. The concentrations 35...
Spontaneous preterm birth (SPB) is affected by various environmental exposures. However, there still an urgent need to efficiently integrate exposomic information build its prediction model and unveil the potential toxic pathways. Here, we conducted a nested case-control study recruiting 30 women with SPB delivery (cases) without (controls) at their early pregnancy. We analyzed biomarkers of external chemical exposure, lipidomics, immunity, resulting in 1081 exposure features. A logistic...
ABSTRACT Exposome has become the hotspot of next-generation health studies. To date, there is no available effective platform to standardize analysis exposomic data. In this study, we aim propose one new framework and build up novel integrated “ExposomeX” expediate discovery “Exposure-Biology-Disease” nexus. We have developed 13 standardized modules accomplish six major functions including statistical learning (E-STAT), exposome database search (E-DB), mass spectrometry data processing...
With the wide application as an alternative for perfluorooctane sulfonate (PFOS), perfluorobutane (PFBS) has been frequently detected in aquatic environment. However, toxicity of PFBS is still poorly understood. This study investigated with using freshwater algae Scenedesmus obliquus ( S. ) indicator, and PFOS was also examined comparison. The results showed that exhibited much lower to than PFOS. EC 50 value higher 1800 mg·L -1 after 7 days exposure PFBS. By contrast, a 158.91 obtained...
Abstract Exposome has become the hotspot of next-generation health studies. To date, there is no available effective platform to standardize analysis exposomic data. In this study, we aim propose one new framework and build up novel integrated “ExposomeX” expediate discovery “Exposure-Biology-Disease” nexus. We have developed 13 standardized modules accomplish six major functions including statistical learning (E-STAT), exposome database search (E-DB), mass spectrometry data processing...