A5047000716- Folate and B Vitamins Research
- Pregnancy and preeclampsia studies
- Cleft Lip and Palate Research
- Gestational Diabetes Research and Management
- Heavy Metal Exposure and Toxicity
- Birth, Development, and Health
- Craniofacial Disorders and Treatments
- Trace Elements in Health
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Air Quality and Health Impacts
- Urological Disorders and Treatments
- Epigenetics and DNA Methylation
- Congenital Anomalies and Fetal Surgery
- Prenatal Screening and Diagnostics
- Heavy metals in environment
- Mercury impact and mitigation studies
- Carcinogens and Genotoxicity Assessment
- Sesame and Sesamin Research
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and Medication Impact
- Liver Disease Diagnosis and Treatment
- Polysaccharides Composition and Applications
- Esophageal and GI Pathology
- Polysaccharides and Plant Cell Walls
Peking University
2016-2025
Fujian Medical University
2025
Union Hospital
2025
National Health and Family Planning Commission
2012-2025
Huazhong University of Science and Technology
2011-2025
Zhejiang Marine Fisheries Research Institute
2016-2025
Tongji Hospital
2011-2025
Wuhu Hit Robot Technology Research Institute
2025
China Three Gorges University
2021-2024
Beijing Friendship Hospital
2021-2024
Persistent organic pollutants (POPs) have been associated with a wide range of adverse health effects. Our case–control study was performed to explore the association between placental levels selected POPs and risks for neural tube defects (NTDs) in Chinese population high prevalence NTDs. Cases included 80 fetuses or newborns NTDs, whereas controls were 50 healthy, nonmalformed newborn infants. Placental concentrations polycyclic aromatic hydrocarbons (PAHs), organochlorine pesticides,...
Abstract Objective To test the hypothesis that a freeze-all strategy would increase chance of live birth compared with fresh embryo transfer in women low prognosis for vitro fertilisation (IVF) treatment. Design Pragmatic, multicentre, randomised controlled trial. Setting Nine academic fertility centres China. Participants 838 IVF treatment defined by ≤9 oocytes retrieved or poor ovarian reserve (antral follicle count <5 serum anti-Müllerian hormone level <8.6 pmol/L). Interventions...
BACKGROUND The prevalence of neural tube defects (NTDs) in northern China is among the highest world. A massive folic acid supplementation program as a specific countermeasure was introduced 2009. Examining trends NTD may provide evidence for future intervention. METHODS Data 2000 to 2014 five counties were obtained through population‐based birth surveillance system. All live births, stillbirths over 20 gestational weeks, and pregnancy terminations because NTDs at any age recorded. by weeks...
Previous animal and human studies suggest potential links between maternal exposure to per- polyfluoroalkyl substances (PFASs) adverse birth outcomes. As spontaneous preterm (SPB) represents a major cause of infant mortality precursor future morbidity, we conducted prospective nested case–control study in Shanxi Province, China investigate the association prenatal PFAS SPB risk, as well associations with biomarkers oxidative stress systemic inflammation. Among 4229 women enrolled during...
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants, and have been reported to be a risk factor for human neural tube defects (NTDs). We investigated the relationship between PAH concentrations in maternal serum NTD offspring using case-control study design, explored link household energy usage characteristics life styles. One hundred seventeen women who had NTD-affected pregnancies (cases) 121 delivered healthy infants (controls) were recruited Northern China....
Rare earth elements (REEs) are ubiquitous in the environment. Animal experiments have shown that many REEs adverse impacts on health of fetuses. However, data from humans scarce. In this study, we examined associations between concentrations 10 maternal serum and risk for fetal neural tube defects (NTDs). The study included 200 pregnant women with pregnancies affected by NTDs 400 healthy fetuses/infants. Fifteen were assessed; them detectable over 60% samples statistical analyses, including...
The effect of maternal copper (Cu) level on the risk spontaneous preterm birth (SPB) remains debate. Therefore, we conducted a prospective nested case-control study in Shanxi Province to investigate relationship between serum Cu concentration and SPB risk, as well potential mediation lipid metabolism.From an overall cohort 4229 women, 147 women affected by at 20-36 gestational weeks (cases) 381 who delivered ≥37 (controls) were included our study. Maternal blood samples collected during 4-22...
This study examined the associations between concentrations of cobalt (Co), iron (Fe), manganese (Mn), molybdenum (Mo), selenium (Se), and zinc (Zn) in placental tissue risks for NTDs with a case-control design consisting 408 fetuses or newborns neural tube defects (NTDs) 593 non-malformed newborns. The Zn Fe were determined by inductively coupled plasma-emission spectrometer other four elements plasma-mass spectrometer. Element presented ng/g µg/g dry weight tissue. levels each six ETEs...
To investigate the prevalence of gestational diabetes mellitus (GDM) and its determinants among pregnant women in Tongzhou district Beijing, China.This study was performed on data collected routine work prenatal health care system from 27,119 Beijing during 2013-2018. Univariate multivariate logistic regression analyses were used to assess factors associated with GDM.The overall GDM 24.24%, it showed an increasing trend over 6 years. A univariate analysis that increased age (p < .001). In...
The non-lipid components of sesame seeds were extracted, roasted at 0, 140, 160, 180, and 200 °C, added to oil, finally made into paste. These different pastes then assessed in terms rheological properties, texture, microstructure. Results indicated that from the defatted meal 160 °C 180 had better quality. Roasting increased storage stability results properties texture analysis revealed paste was thickest. This investigation suggests role on needs be considered. When 160–180 can improve...
To expand the applications of sesame hull waste produced from industrial processing, five cell wall polysaccharide fractions hulls were sequentially extracted with water (WSP), chelator (CSP), sodium carbonate (NSP), 1 mol/L potassium hydroxide (KS1), and 4 (KS4). The preliminary structural characteristics investigated by analytical techniques, such as sugar composition analysis, UV–vis, FT-IR, molecular weight measurement, HSQC. results showed that CSP had main chain xylogalacturonans...