Mark F. Lenzenweger

ORCID: 0000-0002-3464-3333
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About
Contact & Profiles
Research Areas
  • Personality Disorders and Psychopathology
  • Mental Health and Psychiatry
  • Schizophrenia research and treatment
  • Psychotherapy Techniques and Applications
  • Mental Health Research Topics
  • Personality Traits and Psychology
  • Psychosomatic Disorders and Their Treatments
  • Functional Brain Connectivity Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Neuroscience and Music Perception
  • Neural and Behavioral Psychology Studies
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Obsessive-Compulsive Spectrum Disorders
  • Transactional Analysis in Psychotherapy
  • Psychopathy, Forensic Psychiatry, Sexual Offending
  • Genetic Associations and Epidemiology
  • Psychological Testing and Assessment
  • Autism Spectrum Disorder Research
  • Paranormal Experiences and Beliefs
  • Suicide and Self-Harm Studies
  • Mental Health Treatment and Access
  • Bipolar Disorder and Treatment
  • Neurology and Historical Studies
  • Identity, Memory, and Therapy
  • Cognitive Abilities and Testing

Binghamton University
2015-2025

Cornell University
2015-2025

Weill Cornell Medicine
2025

White Plains Hospital
2022

New York Hospital Queens
2022

NewYork–Presbyterian Hospital
2011-2022

New York Proton Center
2013

Ithaca College
2007

Harvard University
1998-2004

Harvard University Press
1998-2000

The authors examined three yearlong outpatient treatments for borderline personality disorder: dialectical behavior therapy, transference-focused psychotherapy, and a dynamic supportive treatment.Ninety patients who were diagnosed with disorder randomly assigned to or treatment received medication when indicated. Prior at 4-month intervals during 1-year period, blind raters assessed the domains of suicidal behavior, aggression, impulsivity, anxiety, depression, social adjustment in multiwave...

10.1176/ajp.2007.164.6.922 article EN American Journal of Psychiatry 2007-06-01

Objective: The authors sought to test the hypothesis that in patients with borderline personality disorder, ventromedial prefrontal cortex and associated regions would not be activated during a task requiring motor inhibition setting of negative emotion. Such finding provide plausible neural basis for difficulty have modulating their behavior emotional states potential marker treatment interventions. Method: A specifically designed functional magnetic resonance imaging (fMRI) activation...

10.1176/appi.ajp.2007.06010126 article EN American Journal of Psychiatry 2007-12-01

10.1016/j.psc.2008.03.003 article EN Psychiatric Clinics of North America 2008-07-17

This report describes 2 studies of the psychometric characteristics primary clinical scales Inventory Personality Organization (IPO; O. F. Kernberg & J. Clarkin, 1995), which assess reality testing, primitive psychological defenses, and identity diffusion, in a nonclinical sample. The 3 IPO display adequate internal consistency good test-retest reliability. Item-level confirmatory factor analysis supported two-factor structure consistent with Kernberg's (1984, 1996) model borderline...

10.1037/1040-3590.13.4.577 article EN Psychological Assessment 2001-12-01

There is no epidemiology of personality disorders (PDs) comparable with that currently available for most other mental disorders. One reason this an Axis II diagnosis usually requires considerable clinical sophistication and it expensive to deploy clinicians rather than trained laypersons examine large community samples. This study explores the feasibility using a 2-stage method in which only subjects who were screened as positive PD would be interviewed by clinicians.University students...

10.1001/archpsyc.1997.01830160073010 article EN Archives of General Psychiatry 1997-04-01

<h3>Background</h3> There exists no empirical literature documenting the long-term longitudinal stability of personality pathology comparable to that available for normal personality. A number test-retest studies have usefully established short-term reliability Axis II measures. However, design is methodologically inadequate resolving issues related disorder (PD). This prospective study evaluated PD features in multiwave perspective. <h3>Methods</h3> Subjects (N=250) drawn from a nonclinical...

10.1001/archpsyc.56.11.1009 article EN Archives of General Psychiatry 1999-11-01

This study was concerned with the relationship between attentional and information-processing deficits positive vs. negative symptoms in schizophrenia. Sixteen schizophrenic patients, rated for extent of symptomatology, 17 depressed 31 normal control subjects were tested on a measure distractibility ability to process under information overload. To establish validity our measures, patients compared subjects. Lowered processing capacity appeared be specific schizophrenia, although specificity...

10.1093/schbul/11.3.397 article EN Schizophrenia Bulletin 1985-01-01

Meehl's (1962, 1990) model of schizotypy and the development schizophrenia implies that structure liability for is dichotomous a "schizogene" determines membership in latent class, or taxon (Meehl & Golden, 1982). The authors sought to determine base rate schizotypy. They applied (1973; Meehl 1982) MAXCOV-HITMAX taxometric analytic procedures subset items from Perceptual Aberration Scale (PAS; Chapman, Raulin, 1978), prominent psychometric index schizotypy, derived randomly ascertained...

10.1037//0021-843x.101.3.567 article EN Journal of Abnormal Psychology 1992-01-01

Schizophrenia is the most devastating form of psychopathology known to humankind, and it has been slow yield clues its origins. Meehl's (1962 , 1990 ) model detailed nature latent liability for schizophrenia as schizotypy provided a major organizing function research on schizophrenia. The integrates genetic environmental contributions well accounting range clinical outcomes, all deriving from genuine illness. Schizotypy, personality organization that harbors schizophrenia, provides framework...

10.1111/j.1467-8721.2006.00428.x article EN Current Directions in Psychological Science 2006-08-01

In this article, we describe the development and preliminary psychometric properties of Structured Interview Personality Organization (STIPO), a semistructured interview designed for dimensional assessment identity, primitive defenses, reality testing, three primary content domains in model personality health disorder elaborated by Kernberg (1984; & Caligor, 2005). Results investigation, conducted clinical sample representing broad range pathology, indicate that identity defenses as...

10.1080/00223890903379308 article EN Journal of Personality Assessment 2009-12-12

The concept of schizotypy represents a rich and complex psychopathology construct. Furthermore, the construct implies theoretical model that has considerable utility as an organizing framework for study schizophrenia, schizophrenia-related (eg, delusional disorder, psychosis-NOS (not otherwise specified), schizotypal, paranoid personality disorder), putative schizophrenia endophenotypes suggested by Rado, Meehl, Gottesman, Lenzenweger, others. understanding (and misunderstanding) model,...

10.1093/schbul/sbu184 article EN Schizophrenia Bulletin 2015-03-01

The Personality Disorder Institute/Borderline Research Foundation randomized control trial (PDI/BPDRF RCT) is a controlled outcome study for borderline personality disorder (BPD), in which 90 participants were to one of three manualized and monitored, active psychosocial treatment conditions. These treatments are: (a) Transference-Focused Psychotherapy (TFP; Clarkin, Yeomans, & Kernberg, 1999), BPD based on object-relational psychoanalytic principles first applied by Kernberg (1996), notable...

10.1521/pedi.18.1.52.32769 article EN Journal of Personality Disorders 2004-02-01

The long-term stability of personality pathology remains an open question. Its resolution will come from prospective, multiwave longitudinal studies using blinded assessments disorders (PD). Informative analysis data requires the application statistical procedures, such as individual growth curve modeling, that can detect and describe change appropriately over time. Longitudinal Study Personality Disorders, which meets contemporary methodological design criteria, provides for this...

10.1001/archpsyc.61.10.1015 article EN Archives of General Psychiatry 2004-10-01

We examined sustained attention in 32 schizotypic and 43 normal control subjects from a large, randomly ascertained nonclinical university population. Schizotypy status was determined with the Perceptual Aberration Scale. Sustained measured Continuous Performance Test-Identical Pairs. Schizotypic displayed significantly poorer sustained-attention performance than did subjects, as by d overall hit rate. Although evidenced greater levels of anxiety depression, not associated these mental state...

10.1037//0021-843x.100.1.84 article EN Journal of Abnormal Psychology 1991-01-01

Background: Eye tracking deficits are one of a few widely validated behavioral markers risk for schizophrenia.Recently, it has been proposed that antisaccade performance may also constitute marker schizophrenia risk.This study investigated whether eye and could be found in another population with putative liability to schizophrenia-nonclinical subjects elevated scores on psychometric index perceptual aberrations.Methods: Subjects were 55 university students who received either high or normal...

10.1001/archpsyc.55.9.837 article EN Archives of General Psychiatry 1998-09-01

It is argued that borderline personality disorder (BPD) represents the interaction of underlying neurobehavioral systems are reflected principally in phenotypic constructs positive emotion, negative and nonaffective constraint (Depue & Lenzenweger, 2001). This preliminary exploratory study sought to examine predictions made from Depue–Lenzenweger model with respect controlled (effortful) information processing BPD. was hypothesized (a) BPD subjects may display deficits on tasks require...

10.1521/pedi.18.5.421.51323 article EN Journal of Personality Disorders 2004-08-01

Paul E. Meehl proposed a model of the cause and pathogenesis schizophrenia related states in early 1960s (Meehl, 1962), which he later revised 1990 1990). His emphasized genetically influenced aberration neural transmission that could eventuate clinical schizophrenia, nonpsychotic schizotypic states, or apparent normalcy depending on coexistence other factors. embodied core ideas diathesis-stressor framework would come to dominate experimental developmental psychopathology for next 40 years....

10.1037/0021-843x.115.2.195 article EN Journal of Abnormal Psychology 2006-05-01
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