A5069559992- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Dialysis and Renal Disease Management
- Diabetes Treatment and Management
- ECG Monitoring and Analysis
- Blood Pressure and Hypertension Studies
- Atrial Fibrillation Management and Outcomes
- Healthcare cost, quality, practices
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Systemic Sclerosis and Related Diseases
- Celiac Disease Research and Management
- Cardiac electrophysiology and arrhythmias
- Health Systems, Economic Evaluations, Quality of Life
- Health Promotion and Cardiovascular Prevention
- Diabetes and associated disorders
- Venous Thromboembolism Diagnosis and Management
- Chronic Disease Management Strategies
- Liver Disease Diagnosis and Treatment
- Ultrasound in Clinical Applications
University Medical Center Groningen
2022-2025
University of Groningen
2022-2025
Zuyderland Medisch Centrum
2023
Maastricht University
2019-2020
Chronic kidney disease (CKD) is often detected late, leading to substantial health loss and high treatment costs. Screening the general population for albuminuria identifies individuals at risk of events cardiovascular (CVD) who may benefit from early start preventive interventions. Previous studies on cost-effectiveness screening were inconclusive, but based survey or cohort data rather than an implementation study, modelled as performed by practitioners home-based screening, included only...
Abstract Background Several clinical trials have shown beneficial effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors on kidney disease progression and cardiovascular morbidity mortality in patients with chronic (CKD) without type diabetes mellitus. However, some subgroups CKD been excluded from participation these trials, such as severely impaired function, dialysis, transplant recipients. Methods The Renal Lifecycle trial (NCT05374291) is a pragmatic, international, multicenter,...
Albuminuria, the abnormal presence of albumin in urine, is a key marker kidney damage and strong predictor cardiovascular outcomes. Its clinical significance has evolved from early historical observations to its current role chronic disease (CKD) detection, risk stratification treatment monitoring. Advances measurement techniques evidence large-scale studies have reinforced prognostic value, particularly guiding interventions such as renin-angiotensin-aldosterone system blockade,...
Key Points Dapagliflozin reduced albuminuria in participants with CKD, reductions being proportional to the risk of disease progression. Residual (at month 4) was linked higher risks primary and kidney end points, no heterogeneity by diabetes status or allocated treatment. Participants residual at 4 had high rates implying need for added therapy long-term cardiovascular benefits. Background Albuminuria is a strong indicator patients CKD. We assessed associations between baseline months after...
Abstract Background Detection and treatment of atrial fibrillation (AF) are important given the serious health consequences. AF may be silent or paroxysmal remain undetected. It is unclear whether general practitioners (GPs) have appropriate equipment optimally utilise it to detect AF. This case vignette study aimed describe current practice explore possible improvements optimise detection. Methods Between June July 2017, we performed an online among Dutch GPs. We at obtaining least 75...
Chronic kidney disease (CKD) is a rising public health problem that may progress to failure, requiring replacement therapy. It also associated with an increased incidence of cardiovascular (CVD). Because its asymptomatic nature, CKD often detected in late stage. Population screening for albuminuria could allow early detection people who benefit from preventive treatment. In case such performed general practitioner (GP) setting, this will result relatively high costs. Home-based might be...
Abstract Background and Aims Although guidelines recommend opportunistic screening for chronic kidney disease (CKD) in individuals with established risk factors, such as diabetes, hypertension, or cardiovascular disease, CKD these remains suboptimal. This study aimed to evaluate the effectiveness of an additional systematic home-based albuminuria program patients at a primary care setting. Method A cross-sectional was performed 10 general practices 5 pharmacies Netherlands between Nov...