A5015372850- Pregnancy and preeclampsia studies
- Public Health and Nutrition
- Cardiac Ischemia and Reperfusion
- Medicinal Plant Research
- Diet and metabolism studies
- Nitric Oxide and Endothelin Effects
- Adipose Tissue and Metabolism
- Heart Rate Variability and Autonomic Control
- Menstrual Health and Disorders
- Bee Products Chemical Analysis
- Healthcare and Venom Research
- Sports and Physical Education Research
- Vitamin D Research Studies
- Pharmacological Effects of Natural Compounds
- Advancements in Transdermal Drug Delivery
- Gestational Diabetes Research and Management
- Maternal and fetal healthcare
- Exercise and Physiological Responses
- Drug-Induced Hepatotoxicity and Protection
- Food and Agricultural Sciences
- Cardiac Arrest and Resuscitation
- Pregnancy and Medication Impact
- Advanced Drug Delivery Systems
- Nigella sativa pharmacological applications
- Cardiac, Anesthesia and Surgical Outcomes
Hasanuddin University
2016-2025
Australian Institute of Tropical Health and Medicine
2016
James Cook University
2016
Objective: Traumatic brain injury is a head that causes dysfunction. This disorder can have bad effect if not treated quickly and appropriately. study aims to examine the extract of Gotukola (Centella asiatica), turmeric (Curcuma longa), black pepper (Piper nigrum) as natural medicines treat problems. Methods: The parameters tested in this included testing memory experimental animals using Y-Maze method, vitro inhibition glutaminase, silico research through molecular docking dynamics on...
Ketogenic diet has been used as supportive therapy in a range of conditions including epilepsy, diabetes mellitus, and cancer.This study aimed to investigate the effects long-term consumption ketogenic on blood gas, hematological profiles, organ functions, superoxide dismutase level rat model.Fifteen male Wistar rats were divided into control (n = 8) 7) groups. Controls received standard contained 52.20% carbohydrates, 7.00% fat, 15.25% protein; meanwhile, group high-fat-low-carbohydrate...
An area of ongoing controversy is the role adenosine to regulate vascular tone in conduit vessels that compliance, and nitric oxide (NO), potassium channels receptor subtypes involved. The aim our study was investigate relaxation rat thoracic aortic rings, effect inhibitors NO, prostanoids, Kv, KATP channels, A2a A2b receptors. Aortic rings were freshly harvested from adult male Sprague Dawley rats equilibrated an organ bath containing oxygenated, modified Krebs-Henseleit solution, 11 mM...
Alzheimer's disease (AD) often leads to dementia, causing cognitive decline and increased care needs. Rivastigmine (RV) is a key AD treatment, but its brain delivery limited by the blood-brain barrier (BBB). Aside from oral, olfactory, intradermal injection (i.d.) routes, application of polymeric microneedles via trigeminal nerve on facial skin as pretreatment, followed solid lipid nanoparticle RV-loaded thermosensitive gel (PMN-SLN-RV-TG), an alternative deal with problems. This study aims...
Cocktail honey is derived from a mixture of (trigona sp.), bee bread, and homogeneous royal jelly. The material has phenolic content rich in antioxidants that are beneficial for women's reproductive health, especially pre-conception, because it can suppress the free radicals body. Antioxidants useful to overcome oxidative damage due body prevent various diseases increasing fertility during pre-conception.This study used DPPH (2,2-diphenyl-1-picrylhydrazyl) test method using UV-vis...
Background: Expansion of multi-drug resistant bacteria in social communities and health facilities has been widely reported. To overcome this ever-growing problem, new antibiotics with novel mechanisms action are urgently required. Purpose: This research was carried out aiming to investigate the vivo antibacterial effect green algae Ulva reticulata against Staphylococcus aureus fruit flies (Drosophila melanogaster) model infection. Methods: Sample dried extracted ethanol using maceration...
Doxorubicin (DOX) is a potent chemotherapy agent; however, its use may lead to cardiac, hepatic, and renal dysfunction. Kleinhovia hospita L extract contains antioxidant compounds that have been shown reduce chemical-induced hepatotoxicity.This study aimed examine the protective effects of sp. DOX acute toxicities.Thirty male rats were assigned following groups: Group I as controls, II was given i.p. injection (25 mg/kg); Groups III, IV, V treated with 100, 250, 500 mg/kg orally for 5 days,...
Lidocaine is an approved local anesthetic and Class 1B antiarrhythmic with a number of ancillary properties. Our aim was to investigate lidocaine's vasoreactivity properties in intact versus denuded rat thoracic aortic rings, the effect inhibitors nitric oxide (NO), prostenoids, voltage-dependent Kv KATP channels, membrane Na+/K+ pump, A2a A2b receptors. Aortic rings were harvested from adult male Sprague Dawley rats equilibrated organ bath containing oxygenated, modified Krebs-Henseleit...
For over four decades the thoracic aortic ring model has become one of most widely used methods to study vascular reactivity and electromechanical coupling. A question that is rarely asked, however, what function does a drug-mediated relaxation (or contraction) isolated rings serve in intact system? The physiological significance adenosine large elastic conduit arteries from wide range species remains largely unknown. We propose increases compliance acute stress states facilitates...
Cycling is a physical exercise that widely performed to improve fitness. Regular will lead adaptations exercise. This adaptation useful in suppressing the production of reactive oxygen stress (ROS) generated response cellular metabolism uses oxygen. Transforming growth factor beta-1 (TGF-β1) plays role increasing ROS, thus, when concentration low, it would an improvement study aims compare levels TGF-β1 between recreational cyclists and sedentary groups. In addition, this research also...
This study aimed to analyze the influence of macronutrient intake, stress, and prostaglandin levels (pgf2α) on adolescent dysmenorrhea incidence.This type is observational analytic with a cohort draft done in January-March 2020 at High junior school 21 Makassar. Respondents this were grade X XI students divided into 64 teenagers who had adolescents did not experience Dysmenrhea. The criteria respondent reproductive age, already experiencing menstruation, knowing time date menstrual cycles...
Introduction: Antituberculosis drugs are associated with hepatic and renal toxicities due to drug’s radical metabolites. Kleinhovia hospita L extract possesses a potent antioxidant capacity that can be beneficial in eradication of oxidative-induced cell damage. This study aimed evaluate the effects K. hydro-alcoholic on biomarkers structure changes liver kidney induced by combination antituberculosis (CAD), comprising isoniazid, rifampicin, pyrazinamide ethambutol Wistar rats. Methods:...
This study was aimed to determine the effect of ginger honey supplementation on cortisol, glutathione, and estrogen levels. The conducted mice that had not yet experienced conception, prior stress induction carried out so they could be continued for human trials at preconception stage subjects who mild stress.
Pemeriksaan hematologi rutin dapat digunakan sebagai penanda inflamasi untuk mengidentifikasi penyakit kardiovaskular, termasuk jantung koroner (PJK). Penelitian ini bertujuan menganalisis gambaran profil pasien yang menjalani angiografi serta hubungannya dengan stenosis lesi arteri coronaria. analitik observasional dirancang desain cross-sectional. Sampel dipilih teknik purposive sampling dan diperoleh 15 subjek penelitian. Tingkat ditentukan sesuai panduan PERKI 2017. Data disajikan dalam...
Seksio sesarea menjadi salah satu operasi besar pada abdomen yang berhubungan langsung dengan perubahan post operatif dalam sistem saraf otonom menyebabkan penurunan pergerakan usus pencernaan. Penelitian ini bertujuan untuk membandingkan efek mengunyah permen karet, mengonsumsi madu dan mobilisasi dini terhadap laju pemulihan fungsi peristaltik waktu kentut pasien seksio sesarea. menggunakan desain Quasi Experimental pendekatan post-test only group design. Sebanyak 78 wanita dipilih melalui...
Circadian rhythms are internal mechanisms that regulate various aspects of the human body's physiology and behaviour influenced by activity, physicality, change time in 24 hours. This study aims to compare oxidant levels hormonal based on differences training times, namely morning evening, badminton athletes. research involved 44 athletes using a purposive sampling technique who were divided into group (n = 22) an evening 22). Melatonin measured Elabscience Kit (No. E-EL-H2016)...