A5027949216- Machine Learning in Materials Science
- Enzyme Structure and Function
- Particle Detector Development and Performance
- Mass Spectrometry Techniques and Applications
- Electrocatalysts for Energy Conversion
- Image Processing Techniques and Applications
- Crystallization and Solubility Studies
- Biochemical and Molecular Research
- Protein Structure and Dynamics
- Nuclear Physics and Applications
- Particle physics theoretical and experimental studies
- Random lasers and scattering media
- TiO2 Photocatalysis and Solar Cells
- Clinical Laboratory Practices and Quality Control
- Spacecraft and Cryogenic Technologies
- CRISPR and Genetic Engineering
- Conservation Techniques and Studies
- Gene expression and cancer classification
- Innovative Microfluidic and Catalytic Techniques Innovation
- Meta-analysis and systematic reviews
- Electron and X-Ray Spectroscopy Techniques
- Delphi Technique in Research
- Copper-based nanomaterials and applications
- Industrial Vision Systems and Defect Detection
- X-ray Diffraction in Crystallography
Lawrence Berkeley National Laboratory
2007-2023
University of California, Santa Cruz
2018
University of California, Berkeley
2018
Joint Center for Artificial Photosynthesis
2014-2015
California Institute of Technology
2015
GlaxoSmithKline (United States)
2008
University of California, San Francisco
2008
Antioch University
2005
Institute of Cancer Research
2002
An approach that enables up to a two order of magnitude reduction in the amount protein required and tenfold time for vapor-diffusion crystallization is reported. A prototype high-throughput automated system was used production diffraction-quality crystals variety proteins from screen 480 conditions using drop volumes as small 20 nL. This results significant cost structure determination, allows larger more efficient screens parameter space. The ability produce rapidly with minimal quantities...
Considerable research and development efforts are being devoted to the efficient generation of solar fuels. A fuels device couples a photoabsorber with catalysts convert energy chemical via reactions such as oxygen evolution (water splitting). Widespread deployment this technology hinges upon discovery new materials through high throughput screening catalysts, discussed in manuscript. We derive an expression for efficiency catalyst that combines catalytic optical properties. Using hybrid...
We have developed an on-the-fly scanning spectrometer operating in the UV-visible and near-infrared that can simultaneously perform transmission total reflectance measurements at rate better than 1 sample per second. High throughput optical characterization is important for screening functional materials a variety of new applications. demonstrate utility instrument light absorber by measuring spectral absorbance, which subsequently used deriving band gap information through Tauc plot analysis.
For the Phase-II Upgrade of ATLAS Detector [1], its Inner Detector, consisting silicon pixel, strip and transition radiation sub-detectors, will be replaced with an all new 100% tracker, composed a pixel tracker at inner radii outer radii. The future include 11,000 sensor modules in central region (barrel) 7,000 forward (end-caps), which are foreseen to constructed over period 3.5 years. construction each module consists series assembly quality control steps, were engineered identical for...
A new design for a double-sided high-pressure diamond anvil cell laser heating set-up is described. The prototype deployed at beamline 12.2.2 of the Advanced Light Source Lawrence Berkeley National Lab. Our compact features shortened mechanical lever arms, which results in more stable imaging optics, and thus user friendly reliable temperature measurements based on pyrometry. modification peak scaling method was implemented pyrometry, including an iterative to determine absolute temperature,...
To decipher and manipulate the 14 000 identified Drosophila genes, there is a need to inject large number of embryos with transgenes. We have developed an automated instrument for high throughput injection embryos. It was built on inverted microscope, equipped motorized xy stage, autofocus, charge coupled device camera, needle mounted speed vertical stage. A novel, micromachined embryo alignment facilitate arrangement eggs. The control system included intelligent dynamic imaging analysis...
Considerable research and development efforts are being devoted to the efficient generation of solar fuels. A fuels device couples a photoabsorber with catalysts convert energy chemical via reactions such as oxygen evolution (water splitting). Widespread deployment this technology hinges upon discovery new materials through high throughput screening catalysts, discussed in manuscript. We derive an expression for efficiency catalyst that combines catalytic optical properties. Using hybrid...
We describe a contact printing approach for microarrays that uses fused-silica capillary tubes with tapered tips pins and pressure/vacuum system to control pin loading, printing, cleaning. The process is insensitive variable environmental factors such as humidity, the small diameter of allows routine from 1536 well source plates. Pin load capacity, 0.2 μL in current system, adjustable by controlling length. More than 2000 spots can be printed per 0.2-μL (<100 pl/spot), densities >12 000...
Abstract To facilitate a direct interface between protein separation by PAGE and identification mass spectrometry, we developed multichannel system that continuously collects fractions as bands migrate off the bottom of gel electrophoresis columns. The device was constructed using several short linear columns, each different percent acrylamide, to achieve power similar long gradient gel. A “Counter Free‐Flow” elution technique then allows continuous simultaneous fraction collection from...
We present herein a custom-made, in situ, multimodal spin coater system with an integrated heating stage that can be programmed spinning and recipes is coupled synchrotron-based, grazing-incidence wide- small-angle x-ray scattering. The coating features adaptable experimental chamber, the ability to house multiple ancillary probes such as photoluminescence visible optical cameras, allow for true characterization correlated data analysis. This enables monitoring of structural evolutions...
Abstract For the Phase-II Upgrade of ATLAS Detector, Inner Detector will be replaced with Tracker (ITk), consisting a pixel and strip tracker. The 17,888 silicon detector modules comprising ITk tracker assembled from sensors flexes readout chips in manual assembly process performed at 20 module sites complex distribution chain, which requires quality control steps to after each step. Sensor visual inspection full sensor area (about 100 cm 2 ) detect log any defects (e.g. scratches, breakdown...
Abstract not Available.
Telomeres occur as multiple repeats of guanine-rich segments at the 3' ends chromosomes.Most telomeric region is double-helical, but a singlestranded overhang protrudes extreme terminus, and guanines in this can associate strongly to form stacked G4 quadruplexes.There intense current interest designing intercalating drug molecules act inhibitors enzyme telomerase which protects tumor cells against telomere loss during replication.Despite interest, little presently known about quadruplex...