A5023036685- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial infections and disease research
- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Animal Behavior and Welfare Studies
- Animal Disease Management and Epidemiology
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Mycobacterium research and diagnosis
- Advanced ceramic materials synthesis
- Enterobacteriaceae and Cronobacter Research
- Neonatal and Maternal Infections
- Salmonella and Campylobacter epidemiology
- Veterinary medicine and infectious diseases
- Rabies epidemiology and control
Royal GD (Netherlands)
2021-2024
De Gezondheidsdienst voor Dieren
2016-2019
The monitoring of antimicrobial resistance (AMR) in bacterial pathogens animals is not currently coordinated at European level. To fill this gap, experts the Union Joint Action on Antimicrobial Resistance and Healthcare Associated Infections (EU-JAMRAI) recommended building Surveillance network Veterinary medicine (EARS-Vet). In study, we (i) identified national systems for AMR (both companion food-producing) among 27 countries affiliated to EU-JAMRAI, (ii) described their structures...
Klebsiella pneumoniae (Kp), a ubiquitous pathogen found in diverse ecological niches, poses threat to human and animal health. Hypervirulent Kp (hvKp) is concerning for its acquisition of virulence antimicrobial resistance genes through plasmids. This study investigates hvKp as cause septicaemia piglets the Netherlands examines role plasmids host association. We collected 41 isolates cultured from necropsies submitted 15 different farms (2013–2020) sequenced them using long-read sequencing....
Polymyxin E (colistin) is a medically important active substance both in human and veterinary medicine. Colistin has been used medicine since the 1950s. Due to discovery of plasmid-borne mcr gene 2015 simultaneously increased importance as last-resort antibiotic, use colistin for animals was scrutinised. Though sales dropped by 76.5% between 2011 2020, few studies evaluated real-world data on patterns different European countries sectors. A survey among veterinarians revealed that 51.9% did...
Major efforts have been made by veterinary professionals to reduce the need for antibiotic use in animals. An online survey launched Federation of Veterinarians Europe (FVE) aimed gather responses from practicing veterinarians with field experience metaphylactic livestock group treatment. Only 17% all (n = 183/1087, species-specific merged) applied treatments 75% or more their treatments. Significantly less were reported mixed practices (p 0.002) and specialized cattle < 0.001) as well small...
Abstract Comparisons between antimicrobial usage (AMU) in humans and food-producing animals are regularly made. The accuracy of such comparisons depends on the indicators used to quantify AMU. Indicators for AMU quantitatively relate use data (the numerator) population denominator). denominator should be a proxy at risk certain period when comparing exposure different populations antimicrobials. Denominators based numbers slaughtered, as commonly correction unit, do not consider time...
Streptococcus suis is an important pig pathogen that can cause severe disease in the post-weaning period. As there are no commercial vaccines available Netherlands, antibiotic treatment often necessary to control disease. S. regarded as one of major causes prescription weaned pigs, but scientific studies supporting this claim with quantitative data lacking. The aim study was obtain insight in, and quantify usage of, antibiotics against weaner pigs at sow farms Netherlands. Three sources were...
Brachyspira hyodysenteriae infection in pigs ('swine dysentery') leads to decreased feed conversion, growth losses and mortality. Current countermeasures have the downside of antibiotic resistance (antibiotics) ecotoxicity (zinc oxide). The aim this study was evaluate effect a novel zinc chelate (Intra Dysovinol (ID)) on clinical signs swine dysentery shedding B under field conditions.In randomised, double-blinded, controlled trial Good Clinical Practice two commercial farms, 58 positive...
Abstract Background Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach. Objectives The objectives were (i) define combinations of animal species, production types, age categories, bacterial specimens and antimicrobials be monitored EARS-Vet (ii) determine test panels able cover most combinations. Methods scope defined by consensus between 26 experts....