A5030141273- Marine Biology and Environmental Chemistry
- Polymer Surface Interaction Studies
- Microplastics and Plastic Pollution
- Marine Ecology and Invasive Species
- Photopolymerization techniques and applications
- Environmental Toxicology and Ecotoxicology
- Molecular Junctions and Nanostructures
- Marine Biology and Ecology Research
- Advanced Polymer Synthesis and Characterization
Ruhr University Bochum
2018-2021
BioSurfaces (United States)
2021
Zwitterionic peptides are facile low-fouling compounds for environmental applications as they biocompatible and fully biodegradable their degradation products just amino acids. Here, a set of histidine (H) glutamic acid (E), well lysine (K) (E) based peptide sequences with zwitterionic properties were synthesized. Both oligopeptides (KE)4K (HE)4H synthesized in d l configurations to test ability resist the nonspecific adsorption proteins lysozyme fibrinogen. The coatings additionally tested...
Layer-by-layer (LbL) assembly is a versatile platform for applying coatings and studying the properties of promising compounds antifouling applications. Here, alginate-based LbL were fabricated by alternating deposition alginic acid chitosan or polyethylenimine to form multilayer coatings. Films prepared with either odd even bilayer numbers investigate if termination affects physicochemical properties, resistance against nonspecific adsorption (NSA) proteins, efficacy. The hydrophilic films,...
Peptide-functionalized surfaces, composed of optimized l-peptides, show a high resistance toward nonspecific adsorption proteins. As l-peptides are known to be prone proteolytic degradation, the aim this work is enhance stability against enzymatic degradation by using all d-peptide mirror image and determine if d-enantiomer retains protein-resistant antifouling properties. Two their images, some them containing nonproteinogenic amino acid α-aminoisobutyric (Aib), were synthesized tested...
Assessing the efficiency of next generation protective marine coatings is highly relevant for their optimization. In this paper, a parallelized microfluidic testing device presented to quantify accumulation model organism (Navicula perminuta) under constant laminar flow. Using automated microscopy in conjunction with image analysis, adhesion densities on tested surfaces could be determined after exposure flow suspended algae 90 min. The optimized protocol assay presented, and reproducibility...
While zwitterionic interfaces are known for their excellent low-fouling properties, the underlying molecular principles still under debate. In particular, role of zwitterion orientation at interface has been discussed recently. For elucidation effect this parameter, self-assembled monolayers (SAMs) on gold were prepared from stoichiometric mixtures oppositely charged alkyl thiols bearing either a quaternary ammonium or carboxylate moiety. The chain length cationic component...
A series of low fouling peptide self-assembled monolayers (SAMs) was developed to understand how the effects subtle sequence alterations determine properties peptide-terminated SAMs and settlement adhesion two model organisms, green alga Ulva linza diatom Navicula perminuta, adsorption different proteins, fibrinogen lysozyme. Insertion bulky, nonproteinogenic amino acid α-aminoisobutyric (Aib) examined for it affects surfaces performance in assays. By exchanging serine (S) (SGKGSSGSS) with...
Reaction scheme of the visible light-induced controlled surface grafting polymerization methacrylate monomers onto organosilane-coated silicon initiated by previously coupled dormant ITXSP groups.