A5080129427- Electrostatics and Colloid Interactions
- Microfluidic and Bio-sensing Technologies
- Polymer Surface Interaction Studies
- Microfluidic and Capillary Electrophoresis Applications
- Geophysical and Geoelectrical Methods
- Proteoglycans and glycosaminoglycans research
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- Electrowetting and Microfluidic Technologies
- Analytical Chemistry and Sensors
- Nanopore and Nanochannel Transport Studies
- Electrospun Nanofibers in Biomedical Applications
- Advanced Cellulose Research Studies
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Lipid Membrane Structure and Behavior
- Cellular Mechanics and Interactions
- Marine Biology and Environmental Chemistry
- Electrochemical Analysis and Applications
- Dendrimers and Hyperbranched Polymers
- Algal biology and biofuel production
- Spectroscopy and Quantum Chemical Studies
- Electrokinetic Soil Remediation Techniques
- Electrical and Bioimpedance Tomography
- Nanocomposite Films for Food Packaging
Leibniz Institute of Polymer Research
2016-2025
Max Bergmann Zentrum für Biomaterialien
2003-2025
Leibniz Association
2006-2015
Columbia University Irving Medical Center
2014
Columbia University
2009
New Jersey Institute of Technology
2001-2007
University of Toronto
2001-2007
Schott (Germany)
2007
Technical University of Munich
2007
University of Tübingen
2006
The interfacial charge on spin-coated films of poly(tetrafluoroethylene-co-2,2-bis(trifluoromethyl)-4,5-difluoro-1,3-dioxole) (Teflon AF) was studied by streaming potential and current measurements in diluted aqueous solutions potassium chloride, hydroxide, hydrochloric acid. ζ surface conductivity were derived from electrokinetic data determined at varied concentrations the electrolytes means novel microslit setup (ref 1: J. Colloid Interface Sci. 1998, 208, 329). results obtained revealed...
Implantation of an embryo induces rapid proliferation and differentiation uterine stromal cells, forming a new structure, the decidua. One salient feature decidua formation is marked increase in maternal angiogenesis. Vascular endothelial growth factor (VEGF)-dependent pathways are active ovary, uterus, embryo, inactivation VEGF function any these structures might prevent normal pregnancy development. We hypothesized that decidual angiogenesis regulated by acting through specific receptors...
The authors report on the characterization of charge formation at supported bilayer lipid membranes (sBLMs) prepared from zwitterionic 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine planar silicon dioxide substrates. charging sBLMs was studied in KCl solutions different ionic strengths between 0.1 and 10 mM by streaming current measurements. In addition, attenuated total reflection Fourier transform infrared spectroscopy fluorescence microscopy were applied to determine concentration membrane...
Electron-beam-induced grafting of hydrophilic polymers was applied to modify PVDF membranes for biomedical applications. Grafting performed by immersing the membrane in an aqueous solution different followed electron-beam irradiation. The two polymer types are able cross-link recombination adjacent radicals formed via Although untreated already quite hydrophilic, modification resulted even lower water contact angles at surface indicating improved wettability. presence functional groups...
Materials capable of directing cell fate by providing spatially-graded mechanical and biomolecular cues are critically important in the reconstitution living matter. Herein, we report a multi-component inkjet bioprinting method that allows for spatially varying composition network properties cell-instructive glycosaminoglycan (GAG)-based biohybrid pure poly(ethylene glycol) hydrogels with unprecedented (50 μm) resolution. The principle relies on covalent crosslinking different polymeric...
Abstract Developing tissue is typically soft, highly hydrated, dynamic, and increasingly heterogeneous matter. Recapitulating such characteristics in engineered cell‐instructive materials holds the promise of maximizing options to direct formation. Accordingly, progress design multiphasic hydrogel expected expand therapeutic capabilities engineering approaches relevance human 3D vitro disease models. Recently pioneered methodologies allow for creation systems suitable template guide dynamic...
Charge build-up at the solid/aqueous interface is a ubiquitous phenomenon that determines properties of interfacial electrical double layers. Due to its unique properties, surface diamond offers an attractive platform investigate charging mechanisms in aqueous solutions. We charge by studying ion sensitivity H-terminated single crystalline conductive The effect monovalent and divalent salts has been probed different pH values. For above 3.5, increasing ionic strength results decrease...
Streaming current measurements were performed on poly(N-isopropylacrylamide)-co-N-(1-phenylethyl) acrylamide [P(NIPAAm-co-PEAAm)] thermoresponsive thin films above and below the transition temperature of polymer (i.e., at 22 4 degrees C, respectively). Electrokinetic (ionic strength 0.01-10 mM KCl, pH 2.5-9.5 in 1 KCl) revealed that charging polymer/aqueous solution interface is determined by unsymmetrical adsorption hydroxide hydronium ions onto Teflon AF substrate supports hydrogel film....
We report a comprehensive formalism for the electrokinetics (streaming current, Istr) at soft multilayered polyelectrolyte films. These assemblies generally consist of succession permeable diffuse layers that differ in charge density, thickness, and hydrodynamic softness. The model, which extends one we recently reported monolayered thin films (Langmuir 2010, 26, 18169−18181), is valid without any restriction number thickness layers, or degree dissociation density ionizable groups they...
Sulfation patterns of glycosaminoglycans (GAG) govern the electrostatic complexation biomolecules and thus allow for modulating release profiles growth factors from GAG-based hydrogels. To explore options related to this, selectively desulfated heparin derivatives were prepared, thoroughly characterized, covalently converted with star-shaped poly(ethylene glycol) into binary polymer networks. The impact GAG sulfation pattern on network characteristics obtained hydrogels was theoretically...
Abstract Incorporation of sulfated glycosaminoglycans (GAGs) into cell‐instructive polymer networks is shown to be instrumental in controlling the diffusivity and activity growth factors. However, a subtle balance between local retention release factors needed effectively direct cell fate decisions. To quantitatively unravel material characteristics governing these key features, GAG content sulfation pattern star‐shaped poly(ethylene glycol) (starPEG)–GAG hydrogels are herein tuned control...
Zwitterionic peptides are facile low-fouling compounds for environmental applications as they biocompatible and fully biodegradable their degradation products just amino acids. Here, a set of histidine (H) glutamic acid (E), well lysine (K) (E) based peptide sequences with zwitterionic properties were synthesized. Both oligopeptides (KE)4K (HE)4H synthesized in d l configurations to test ability resist the nonspecific adsorption proteins lysozyme fibrinogen. The coatings additionally tested...