A5013919981- Pharmaceutical Economics and Policy
- Healthcare Systems and Public Health
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical studies and practices
- Biosimilars and Bioanalytical Methods
- Economic and Financial Impacts of Cancer
- Chronic Lymphocytic Leukemia Research
- Dermatology and Skin Diseases
- Erythropoietin and Anemia Treatment
- Retinal Diseases and Treatments
- Asthma and respiratory diseases
- Cancer Treatment and Pharmacology
- Pneumonia and Respiratory Infections
- Antifungal resistance and susceptibility
- Diabetes Management and Research
- Advanced Breast Cancer Therapies
- Protein Degradation and Inhibitors
- Diagnosis and treatment of tuberculosis
- Multiple Myeloma Research and Treatments
- Cancer Immunotherapy and Biomarkers
- Neutropenia and Cancer Infections
- Fungal Infections and Studies
- Schizophrenia research and treatment
- Diabetes Treatment and Management
- Intraocular Surgery and Lenses
Ministry of Health of the Russian Federation
2024-2025
Moscow State University of Medicine and Dentistry
2022-2024
Moscow State University of Food Production
2014-2023
Institute for Clinical and Economic Review
2022
National Research Institute of Public Health named after N.A. Semashko
2020-2021
Sechenov University
2013
Clinical Hospital No. 8
2011
Introduction. In the system of higher medical and pharmaceutical education, there is a growing need to implement new educational technologies. For institutions, virtual reality (VR) represents promising technology enhance student engagement adapt them practical conditions. Objective. To evaluate effectiveness using VR technologies in process students studying pharmacy. Material methods. The study was conducted as part "Pharmaceutical Propedeutic Internship" simulator "Virtual Full-Service...
Objective: To evaluate the efficacy of neurotropic action cortexin in models mental and physical developmental delays rat offspring. Methods: The properties bovine brain cortex polypeptides were studied using two rats: toxic CNS damage (oral administration ethanol during last week pregnancy) neonatal trauma (ischemia-hypoxia). drug was administered intramuscularly or rectally as suppositories for 20 days. Treatment evaluated mNSS scale, open field, rotarod, adhesive removal tests. A...
Orphan diseases is a significant socio-economic burden for both global and Russian health care systems. The of disease metrics introduced by WHO, such as DALY, QALY, HALE, can be useful tool building economic models prognoses, well medicine funding distribution. However, it very difficult to standardize heterogeneous group rare talk about the cost-effective treatment options search, in cases where patients with an orphan may have only one pathogenetic therapy option. Much work needs done...
The prevalence of comorbidity — asthma and atopic dermatitis is not understood well yet. More severe processes decreasing quality life increasing a social-economic burden disease are occurred in such kind comorbidity. Aim: an evaluation economic non-control combination with the local conditions. Materials methods. Analysis has been performed for adult patients; bottom-up approach costs was used. Direct medical non-medical as indirect were calculated two models: Model 1 current practice...
Procurement of medicines reflects the demand and frequency prescribing certain drugs, which makes it possible to assess quality medical care compliance with standards. The Russian pharmaceutical market is dynamically developing expanding, therefore, commercial sector drug circulation a significant part should be studied along public procurement. Given number patients diagnosed diabetes mellitus (DM) in our country, we considered appropriate interesting analyze structure volume turnover...
Modern anticancer therapy due to its intensity and molecular biology orientation allows achieving higher efficiency theoretically reducing the incidence of complications. However, increase in efficacy modern oncology really exists, but complication frequency, unfortunately, is far from being solved. In many respects problems diagnosis, treatment complications monitoring are associated with impact on complex physiological processes occurring oncological patient. Timely implementation adequate...
Purpose of the study . Conducting an assessment economic consequences (clinical and analysis) when conducting cytogenetic studies before prescribing various first-line treatment regimens for multiple myeloma (MM). Materialsand methods. The pharmacoeconomic was carried out using method cost analysis, “cost-effectiveness” within framework State Guarantee Program (SGP). Results. A review literature demonstrated that a limited number data are currently available on clinical effectiveness...
Aim. To perform pharmacoeconomic evaluation of chemotherapy schemes GC (gemcitabine, cisplatin) and GemCarbo carboplatin) in comparison with immunotherapy drugs atezolizumab, pembrolizumab or avelumab patients locally advanced metastatic urothelial carcinoma. Materials methods. Pharmacoeconomic cost–effectiveness analysis, sensitivity analysis context changes initial model parameters were performed. Results. Literature data allows to make a conclusion better clinical effectiveness safety...
Cystic fibrosis (CF) is a hereditary disease characterized by impaired functioning of the glands external secretion, phenomena maldigestion, malabsorption, chronic inflammation in bronchopulmonary system, which negatively affects nutritional status. Among patients with CF, regardless age, there high prevalence malnutrition, has multifactorial nature and leads to somatic psychological consequences, significantly worsens course prognosis disease, reduces quality life. The high-risk group...
Diabetic macular edema (DME) is a degenerative disease of the area in diabetes mellitus and can lead to vision loss, disability, significantly reduced quality life. Faricimab only bispecific antibody for DME therapy that targets two pathogenic pathways (Ang-2 VEGF-A).
Depression is a leading cause of disability and reduced work capacity worldwide. The monoamine theory the pathogenesis depression has remained dominant for many decades, however, drugs developed on its basis have limited efficacy. Exploring alternative mechanisms underlying this pathology could illuminate new avenues pharmacological intervention. Targeting glutamatergic pathways in CNS, particularly through modulation NMDA AMPA receptors, demonstrates promising results. This review presents...
Background. Currently, sufficient information has been accumulated the literature on clinical effectiveness and safety of favipiravir in adult patients with COVID-19, including cases its use intensive care units comorbid patients. This article summarizes latest published data from studies, systematic reviews meta-analyses, real-life practice. A number studies have conducted a pharmacoeconomic evaluation COVID-19. Objective. To evaluate efficacy non-severe forms COVID-19 Russian hospital...
2021 marks the 100th anniversary of discovery insulin, an event that forever changed lives people with diabetes mellitus. At present patients around world experience miracle insulin therapy every day. A disease used to kill children and teenagers in 2 years 1920 has become a can be controlled possibility lead long productive life. Over past century, great Banting, Best Collip saved millions lives. This review is devoted history development its further improvement: from moment days. Various...
Objective: a comparative clinical and economic analysis of posaconazole (Noxafil) for invasive mycoses (IM) prevention in patients with severe neutropenia during treatment acute myeloid leukemia or myelodysplastic syndrome Russia. Materials methods. A model was constructed that takes into account the use various mediactions: posaconazole, voriconazole fluconazole. Cost estimation IM carried out considering direct medical costs prevention, therapy, hospital stay, therapeutic diagnostic...
Objectives : to perfom analysis of the clinical efficacy and safety using monofocal IOLs in surgical treatment cataracts adult patients. Material methods . In available sources (databases Cochrane Library Medline) a search was conducted evaluate effectiveness cataract surgery patients according PICO(S) regimen. A literature review July 2018 for keywords “intraocular lenses” “cataract” following filters: trial, randomized meta-analysis, systematic (clinical review). Posting languages:...