Jan Svedenhag

ORCID: 0000-0002-3569-8766
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About
Contact & Profiles
Research Areas
  • Cardiovascular and exercise physiology
  • Muscle metabolism and nutrition
  • Sports Performance and Training
  • High Altitude and Hypoxia
  • Exercise and Physiological Responses
  • Adipose Tissue and Metabolism
  • Heart Rate Variability and Autonomic Control
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Pharmacological Effects and Assays
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Effects of Exercise
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • ECG Monitoring and Analysis
  • Cardiac pacing and defibrillation studies
  • Erythropoietin and Anemia Treatment
  • Bacterial Infections and Vaccines
  • Hormonal Regulation and Hypertension
  • Body Composition Measurement Techniques
  • Physical Education and Pedagogy
  • Analog and Mixed-Signal Circuit Design
  • Cardiac Structural Anomalies and Repair
  • Sports and Physical Education Studies
  • Brucella: diagnosis, epidemiology, treatment
  • School Health and Nursing Education

Saint Göran Hospital
2006-2024

Karolinska Institutet
1987-2014

Karolinska University Hospital
1992-2004

Northwick Park Institute for Medical Research
2000

Northwick Park Hospital
2000

Stockholm University College of Music Education
2000

University of Copenhagen
1985-1995

Herlev Hospital
1985

Swedish Defence Research Agency
1985

University of Tsukuba
1983

The aim of this study was to characterize Kenyan runners in regard their oxygen uptake and blood ammonia responses when running. Untrained boys (14.2±0.2 years) Scandinavian were included for comparison. studies performed at altitude (∼2.000 m.a.s.l.) and, several runners, sea level as well. At sedentary adolescent had a mean maximal (Vo 2max ) 47 (44–51) ml · kg −1 min , whereas similarly aged regularly walking or running but not training competition reached above 62 (58–71) Vo . active...

10.1111/j.1600-0838.1995.tb00037.x article EN Scandinavian Journal of Medicine and Science in Sports 1995-08-01

10.1007/bf00428962 article EN European Journal of Applied Physiology and Occupational Physiology 1982-06-01

BERGH, U., B. SJÖDIN, A. FORSBERG, and J. SVEDENHAG. The relationship between body mass oxygen uptake during running in humans. Med. Sci. Sports Exerc., Vol 23, No. 2, pp. 205–211, 1991. Oxygen treadmill was measured at submaximal maximal intensities six different groups of endurance athletes (N = 134) seven endurance-trained men. (M) (VO2) evaluated by deriving the exponent b equation VO2 a.Mb. Thus, if 1, increases proportion to per kg is independent mass; b<1, then inversely related mass....

10.1249/00005768-199102000-00010 article EN Medicine & Science in Sports & Exercise 1991-02-01

The study comprises data on 12 Scandinavian runners who had either trained for two weeks in Kenya ( n = 6; ∼2000 meters above sea level (m.a.s.l.)) or Portugal (s.l.)) and 13 Kenyan (9 junior 4 senior) living training at m.a.s.l. Muscle biopsies were taken before after the camps once from vastus lateralis (v.l.) gastrocnemius muscles. fiber size composition similar various groups (4.6–5.1 × 10 3 μm 2 ; ST ∼60–70%; FTa 30–40%; FTb &lt; 6.0%) with a tendency some more (∼5%) fibers muscle. Mean...

10.1111/j.1600-0838.1995.tb00038.x article EN Scandinavian Journal of Medicine and Science in Sports 1995-08-01

The effect of water immersion on cardiorespiratory and blood lactate responses during running was investigated. Wearing a buoyant vest, 10 trained runners (mean age 26 yr) ran in at four different specified submaximal loads (target heart rates 115, 130, 145, 155-160 beats.min-1) maximal exercise intensity. Oxygen uptakes (VO2), rates, perceived exertion, concentrations were measured. Values compared with levels obtained treadmill running. For given VO2, rate 8-11 beats.min-1 lower than...

10.1249/00005768-199210000-00014 article EN Medicine & Science in Sports & Exercise 1992-10-01

Physiological characteristics of elite runners from different racing events were studied. Twenty-seven middle- and long-distance two 400-m belonging to the Swedish national team in track field divided, according their distance preferences, into six groups 400 m up marathon. The maximal oxygen uptake (VO2 max, ml X kg-1 min-1) on treadmill was higher longer main except for marathon (e.g., 800-1500-m group, 72.1; 5000-10,000-m 78.7 min-1). Running economy evaluated measurements at 15 km/h 15)...

10.1055/s-2008-1025916 article EN International Journal of Sports Medicine 1984-10-01

Arterial desaturation during exercise is common in endurance-trained athletes, a phenomenon often more pronounced when the muscle mass engaged large. With this background, present study monitored seven international-level cross country skiers performing on treadmill while running (RUN), double poling (DP; upper body exercise) and diagonal skiing (DIA; arm leg exercise). Static dynamic lung function tests were performed oxygen uptake was measured submaximal maximal exercise. Lung variables...

10.1111/j.1600-0838.2006.00592.x article EN Scandinavian Journal of Medicine and Science in Sports 2006-11-07

Increasing the haemoglobin concentration ([Hb]) improves oxygen transport capacity but it also increases viscosity of blood. The influence changes in [Hb] and on submaximal exercise maximal aerobic power was investigated eight healthy males varying states training with a normal resting ([Hb] r ), ranging from 123 to 178 g] ‐1 . subjects were venesected five times (450 ml per unit) tests performed anaemic state. After 5–7 weeks, when had returned ‘normal’ value, stepwise re‐transfusion three...

10.1111/j.1748-1716.1987.tb08038.x article EN Acta Physiologica Scandinavica 1987-01-01

The aim of the present study was to investigate whether levels malateaspartate and alpha‐glycerophosphate shuttle enzymes in human skeletal muscle are affected by endurance training. approach used compare six untrained endurance‐trained subjects as well through performing a longitudinal training on eight subjects. Biopsy samples were obtained from lateral part quadriceps femoris muscle. trained muscles characterized higher oxidative (55%) enhanced capillary supply (30%). In both...

10.1111/j.1748-1716.1986.tb07993.x article EN Acta Physiologica Scandinavica 1986-11-01

The safety and efficacy of SonoVue (also referred to as BR1), a new contrast agent for delineating endocardial border the left ventricle after intravenous administration, was assessed. Two hundred eighteen patients with suspected coronary artery disease undergoing fundamental echocardiography assessment were enrolled in prospective multicenter, single blind, cross‐over study random sequence allocation four different doses SonoVue. Endocardial definition apical parasternal views scored O =...

10.1111/j.1540-8175.2000.tb01223.x article EN Echocardiography 2000-11-01

10.1007/bf00705073 article EN European Journal of Applied Physiology and Occupational Physiology 1992-01-01

Effects on erythropoiesis and blood pressure as well physical performance mental effects were studied in 15 healthy subjects during intermittent exposure to normobaric hypoxia corresponding either 2000 m (6 persons) or 2700 (9 above sea level; another group (5 also served controls at normoxia. The concept “live hightrain low” was used for 10 d consecutively the 12 h/d. Blood pO 2 oxygen saturation significantly decreased hypoxia. [Hb] Hct after then returned pre‐study levels. Erythropoietin...

10.1111/j.1600-0838.1998.tb00182.x article EN Scandinavian Journal of Medicine and Science in Sports 1998-06-01

The effect of physical training on muscle sympathetic activity (MSA) was studied by comparing resting levels MSA in 8 well‐trained racing cyclists and age‐matched untrained subjects (mean age 22 yrs). In addition, determined for 5 before after an 8‐week program cycle erogmeters (training group). Recordings were made from the peroneal nerve at knee with subject recumbent position. characterized a clearly higher maximal oxygen uptake (VO 2 max) lower heart rate submaximal exercise (180 W) than...

10.1111/j.1748-1716.1984.tb07413.x article EN Acta Physiologica Scandinavica 1984-04-01

The effect of short‐term altitude training on sea‐level physiological characteristics in elite runners was investigated. Seven middle‐distance (6 men, 1 woman) belonging to the Swedish national team (mean age 23 years) spent 2 weeks at 2000 m above sea level Kenya. Treadmill tests were performed before and 6 12 d after sojourn. Six other (4 women) had a corresponding sojourn Portugal (control group). Ro (1 man, Kenya group omitted from study because gastroenteritis. maximal oxygen uptake (VO...

10.1111/j.1600-0838.1991.tb00297.x article EN Scandinavian Journal of Medicine and Science in Sports 1991-12-01

The effect of endurance training on skeletal muscle myoglobin concentration in man was investigated. 8 healthy sedentary males (20–31 yrs) trained cycle ergometers 40 min/day, 4 days a week for weeks. work consisted continuous exercise at load that during the last 5 weeks corresponded to 75% pretraining maximal oxygen uptake (VO 2 max). program resulted 7% increase VO max ( p &lt;0.01). activities mitochondrial enzymes citrate synthase (CS), succinate dehydrogenase (SDH) and cytochrome c...

10.1111/j.1748-1716.1983.tb07199.x article EN Acta Physiologica Scandinavica 1983-02-01

The effects of long‐term altitude training on and sea‐level physiological characteristics in elite endurance athletes were investigated. Seven Swedish cross‐country skiers (five men, two women; mean age 27 years) spent 1 month at 1900 m above sea level Italy. Rollerski treadmill tests performed before 5 11 days after the sojourn; three also altitude. Before 1, 35 camp, echocardiographic blood volume measurements performed. heart rates both maximal ( P &lt; 0.05) submaximal 0.01) work loads...

10.1046/j.1365-201x.1997.00204.x article EN Acta Physiologica Scandinavica 1997-08-01

To minimize the influence of body mass on oxygen uptake (VO2) during running, submaximal and maximal VO2 should preferentially be expressed as ml.kg-0.75.min-1. In this study, levels such body-mass-modified running economy were investigated at different velocities in elite runners related to step lengths anthropometric measures. Twenty-six Swedish National Team middle- long-distance performed (4 velocities) treadmill tests. 17 repeated (2-4) tests within 6 months. The (VO2max; 214 vs 202...

10.1055/s-2007-1021065 article EN International Journal of Sports Medicine 1994-08-01

The influence of physical training on responses to i.v. adrenaline infusions and exercise were investigated in 10 endurance‐trained men (mean age: 35 y; Vo 2 max: 61.9 ml kg ‐1 min ) age‐matched sedentary controls (36 y, 37.5 ). untrained subjects reinvestigated after a 4 month period which increased their max by 18%. Resting heart rate diastolic blood pressure significantly lower the trained state. venous plasma concentrations attained during (4 dose levels, 8 each) well‐trained than...

10.1111/j.1748-1716.1986.tb07853.x article EN Acta Physiologica Scandinavica 1986-04-01

Sixteen male subjects (20–31 yr) trained for 8 wk on cycle ergometers. Eight of the were treated during training period with beta-adrenoceptor blocker propranolol (160 mg/day). During all pre-and posttraining tests, uninfluenced by medication. Training-induced increases in VO2max and decreases blood lactate norepinephrine concentrations at submaximal exercise not different between beta-blockade placebo groups. The activities mitochondrial enzymes citrate synthase (CS), succinate...

10.1152/ajpendo.1984.247.3.e305 article EN AJP Endocrinology and Metabolism 1984-09-01
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