- Transplantation: Methods and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Organ Transplantation Techniques and Outcomes
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Reconstructive Surgery and Microvascular Techniques
- Global Health and Surgery
- Surgical Sutures and Adhesives
- Cardiac Imaging and Diagnostics
- Corrosion Behavior and Inhibition
- Acute Myocardial Infarction Research
- Electronic Health Records Systems
- Cardiac Valve Diseases and Treatments
- Surgical site infection prevention
- Infective Endocarditis Diagnosis and Management
- Medical Malpractice and Liability Issues
- Cardiac Ischemia and Reperfusion
- Respiratory Support and Mechanisms
- Climate Change and Health Impacts
- Cardiovascular Disease and Adiposity
- Renal Transplantation Outcomes and Treatments
- Coronary Interventions and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Hydrogen embrittlement and corrosion behaviors in metals
- Clinical Nutrition and Gastroenterology
University of Ulster
2021-2024
Royal Victoria Hospital
2021-2024
Papworth Hospital
2020-2024
New Cross Hospital
2024
Papworth Hospital NHS Foundation Trust
2021-2023
St George's, University of London
2011-2015
St George's Hospital
2012-2015
Robert Bosch Hospital
2014
Basildon Hospital
2014
Maastricht University
2011
Background— Coronary spasm can cause myocardial ischemia and angina in patients with those without obstructive coronary artery disease. However, provocation tests using intracoronary acetylcholine administration are rarely performed clinical routine the United States Europe. Thus, we assessed usefulness, angiographic characteristics, safety of testing white unobstructed arteries. Methods Results— From September 2007 to June 2010, a total 921 consecutive (362 men, mean age 62±12years) who...
Background— Intergenic variations on chromosome 4q25, close to the PITX2 transcription factor gene, are associated with atrial fibrillation (AF). We therefore tested whether adult hearts express and variation in expression affects cardiac function. Methods Results— mRNA for isoform c was expressed left atria of human mouse, levels right atrium ventricles being 100-fold lower. In mice heterozygous Pitx2c ( +/− ), 60% wild-type morphology function were not altered, except slightly elevated...
Sir:FigureFingertip injuries represent approximately two-thirds of pediatric hand injuries, with nailbed quoted to 15 24 percent cases.1 Although a variety methodologies exist, repair is usually undertaken fine absorbable sutures, nail replacement between the eponychial fold, and suture fixation.2 Nail or foil placement carries theoretically higher morbidity risk (e.g., infection) that may require general anesthetic surgical intervention. We therefore investigated complications in plastic...
Concurrent occurrence of coronary artery disease, aortic valve pathology, and abdominal aneurysm presents a complex challenge for surgical intervention. Traditional staged approach bears considerable risks, including two major operations potential rupture during initial surgery. This case report outlines the procedural intricacies successful outcome simultaneous to address all pathologies, offering insights into operative considerations.
The COVID-19 pandemic has had a profound impact on healthcare worldwide. Emergency presentations to hospital unrelated have generally, significantly reduced. At our centre we observed substantial surge in the number of patients presenting with type A Aortic dissection (TAD). Despite having warmest April record, performed 8 TAD repairs, more than any single month over last decade. On histopathological examination there is no evidence direct link between virus. We hypothesise that this relates...
Sir: We previously published a retrospective study of pediatric plastic surgery patients (n = 111) who underwent 6-0 Vicryl Rapide (Ethicon, Inc., Somerville, N.J.) nail-bed repairs with nail replacement/foil placement (replacement group, n 51) versus where the was discarded (discarded 60).1 There low overall complications rate (10.8 percent), which greater in replacement group (17.6 percent) than (5 (p < 0.001). Of note, were primarily minor: delayed wound healing (7.2 defined as unhealed...
Abstract Transplantation of donation after circulatory death (DCD) donor hearts is gaining acceptance. However, DCD heart selection has been understandably cautious. We report a case reconditioning using thoraco-abdominal normothermic regional perfusion in 46-year-old who suffered irreversible brain injury following emergency type-A aortic dissection repair. The was procured with cold preservation and directly transplanted into 63-year-old male bridged to transplant extracorporeal life...
Surgical approaches to major pulmonary resections have evolved from thoracotomy multiportal video-assisted thoracoscopy (VATS) and subsequently uniportal VATS. The efficacy of this progress has been validated in a multitude publications demonstrating reductions complications, patient perception pain, postoperative length stay. More recent advances include subxiphoid extrathoracic access nonintubated, opioid-free anesthesia. Early demonstrated promising results with respect safety, technical...
SARS-CoV-2 is a novel coronavirus which can cause respiratory failure requiring ventilatory support. We describe the first documented case of life-threatening upper airway obstruction due to retained secretions around nasogastric (NG) tube in patient suffering from this disease who was managed with prolonged continuous positive airways pressure (CPAP). This highlights need for awareness development an mass tenacious patients and develop preventative strategies order prevent avoidable...
Introduction: Cardiac allograft vasculopathy (CAV) remains a major problem for heart transplant (HTx) recipients, limiting their long-term survival. Our centre has performed the world’s largest series of donation after circulatory-determined death (DCD) HTx. Five-year survival is equivalent to brainstem-determined (DBD) However, there no information on CAV in DCD HTx recipients. We sought evaluate incidence our cohort Methods: All recipients at between February 2015 and December 2019 who had...