A5044446288- Hair Growth and Disorders
- Dermatologic Treatments and Research
- Dermatology and Skin Diseases
- Medicine and Dermatology Studies History
- Hereditary Neurological Disorders
- Skin and Cellular Biology Research
- RNA regulation and disease
- Dyeing and Modifying Textile Fibers
- Skin Protection and Aging
- Genetic and rare skin diseases.
- Cutaneous Melanoma Detection and Management
- Nail Diseases and Treatments
- Diagnosis and Treatment of Venous Diseases
- Melanoma and MAPK Pathways
- Body Contouring and Surgery
- T-cell and Retrovirus Studies
- Advanced Breast Cancer Therapies
- CAR-T cell therapy research
- Urticaria and Related Conditions
- Allergic Rhinitis and Sensitization
- Forensic Toxicology and Drug Analysis
- Uterine Myomas and Treatments
- Connective Tissue Growth Factor Research
- Facial Rejuvenation and Surgery Techniques
- Systemic Sclerosis and Related Diseases
Johns Hopkins Medicine
2016-2025
Johns Hopkins University
2016-2025
Meharry Medical College
2018
Johns Hopkins Hospital
2016
The current classification for alopecia areata (AA) does not provide a consistent assessment of disease severity.To develop an AA severity scale based on expert experience.A modified Delphi process was utilized. An advisory group 22 clinical experts from the United States formed to this scale. Representatives pharmaceutical industry provided feedback during its development.Survey responses were used draft criteria, aspiring simple that may be easily applied in practice. A consensus vote held...
Background: Pruritus is a common disease symptom with variety of etiologies known to reduce patient quality life. We aimed characterize the racial and gender differences in presentation pruritus for itch-related visits both within single institution nationally. Methods: Cross sectional study patients ≥ 18 years old seen at Johns Hopkins Health System between 1/1/12 1/1/18. Results were compared data from 2005-2011 National Ambulatory Medical Care Survey (NAMCS) (NHAMCS). Results: Our...
Central centrifugal cicatricial alopecia (CCCA) is a progressive scarring predominately occurring in women of African descent.1 The progression hair loss insidious, often the absence clinical signs overt inflammation. As result, end stage fibrosis occurs at rate disproportionate to inflammation, finding common class disorders termed fibroproliferative (FPDs).2 Staging CCCA based on distribution, frontal (type a) or vertex b) location, and extent area affected scalp scaled numerically from...
Background: Central centrifugal cicatricial alopecia (CCCA) is a progressive scarring alopecia. No disease activity scale exists, making assessment of therapeutic intervention difficult. Objective: This study introduces the CCCA Clinical Assessment Tool (C-CAT), novel that quantifies symptom severity to facilitate tailored treatment and track progression. Methods: A retrospective review patients with were assessed on degree pruritus, erythema, pain, progression, scalp resistance, each scored...
Importance Central centrifugal cicatricial alopecia (CCCA) is a scarring predominantly affecting Black female individuals. Current conventional treatments target inflammation but not the underlying fibrotic processes, often leading to permanent hair loss. Objective To investigate associations of low-dose oral metformin, an antidiabetic medication with antifibrotic properties, clinical symptoms and scalp gene expression patterns in patients CCCA. Design, Setting, Participants This...
Krokodil is a commonly used street name for desomorphine, an injectable opioid derivative that associated with severe dermatologic effects. We report case of woman who had extensive ulcerations after single use this narcotic. To our knowledge, the first cutaneous manifestations krokodil in literature.
Characteristics and Affected PatientsCentral centrifugal cicatricial alopecia (CCCA) is a disease characterized by permanent hair loss in the crown region of scalp, inflammation, scarring.It occurs almost exclusively black women aged 30 to 55 years.It estimated that CCCA may affect up 15% women, but precise number individuals affected general population unknown. Causes
Patients with metastatic acral lentiginous melanoma (ALM) suffer worse outcomes relative to patients other forms of cutaneous (CM), and do not benefit as well approved therapies. Identification cyclin-dependent kinase 4 6 (CDK4/6) pathway gene alterations in >60% ALMs has led clinical trials the CDK4/6 inhibitor (CDK4i/6i) palbociclib for ALM; however, median progression free survival CDK4i/6i treatment was only 2.2 months, suggesting existence resistance mechanisms. Therapy ALM remains...
This cohort study examines the risk of uterine leiomyomas in black women with central centrifugal cicatricial alopecia.