A5091272536- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- RNA modifications and cancer
- Amino Acid Enzymes and Metabolism
- Molecular Sensors and Ion Detection
- Hearing, Cochlea, Tinnitus, Genetics
- Sulfur Compounds in Biology
- Sinusitis and nasal conditions
- Infectious Diseases and Mycology
- Brain Metastases and Treatment
- Peptidase Inhibition and Analysis
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
Eye & ENT Hospital of Fudan University
2019-2022
Central South University
2015
Changsha University
2015
Obstetrics and Gynecology Hospital of Fudan University
2014
A phthalimide-based fluorescent probe for thiols with a large Stokes shift (161 nm) was developed <italic>via</italic> PET and ESIPT mechanisms. This displayed good selectivity high sensitivity toward thiols. Imaging intracellular successfully achieved in living cells.
Background Laryngeal squamous cell carcinoma (LSCC) is one of the world’s most common head and neck cancer. However, immune infiltration phenotypes LSCC have not been well investigated. Methods The multi-omics data were obtained from TCGA (n=111) GEO (n=57) datasets. infiltrations 24 populations calculated using GSVA method. Then samples with different infiltrating patterns clustered, differences Results Patients clustered into high-infiltration low-infiltration groups. scores cells higher...
This study is aimed at investigating the expressions and prognostic values of secreted or membrane-located proteins (SMPs) in laryngeal squamous cell carcinoma (LSCC). The correlations between SMPs immune cells' infiltrations were also investigated. expression data normal LSCC samples obtained from TCGA GEO datasets. differentially expressed identified, their analyzed. biological functions worse-survival-related explored. LASSO regression, Cox multivariate analysis, nomogram used to...
Most previous studies are separate dosimetric analyses of conductive or sensorineural hearing loss, and they not conducive to a comprehensive assessment auditory radiation damage.Our study aimed evaluate the long-term incidence loss (SNHL) (CHL) in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated therapy (IMRT), investigate relationship between SNHL CHL patient factors, treatment-related dose parameters.Seventy (117 ears) NPC, who were also treated IMRT our hospital...
Background Sinonasal squamous cell carcinoma (SNSCC) is a rare malignancy with varied outcomes. The aim of this study was to develop nomogram for predicting survival patients SNSCC. Methods From the Surveillance, Epidemiology, and End Results database, we identified 1766 diagnosed SNSCC between 2004 2015. Patients were randomly separated into training set validation in 4:1 ratio. An external also performed by 74 who had been treated our department. We used build based on stratified...
Background The survival difference between de‐novo sinonasal squamous cell carcinoma (DN‐SNSCC) and SCC arising from inverted papillomas (IPs) is unclear. purpose of this study was to compare the outcomes DN‐SNSCC IP‐transformed SNSCC (IP‐SNSCC) patients. Methods In retrospective review, we compared IP‐SNSCC cases Eye ENT Hospital Fudan University 2010 2017. A total 162 patients (39 123 DN‐SNSCC) were included in our study. Demographics, tumor characteristics, treatment, clinical analyzed....
Objective To investigate the clinical features and survival status of mucosal melanoma nasal cavity paranasal sinuses to analyze prognostic factors.Methods A retrospective analysis was performed on data 94 patients with treated from January 2000 December 2012.Of patients,50 were male,and 44 female.The median age onset 60 years (range,26-85 years).The primary sites (86 patients),maxillary sinus (7 patients),and nasopharynx (1 patient).Cervical lymph node metastasis observed in 10 before...