A5008128791- Molecular Sensors and Ion Detection
- Nanoparticles: synthesis and applications
- Natural Antidiabetic Agents Studies
- Luminescence and Fluorescent Materials
- Natural product bioactivities and synthesis
- Curcumin's Biomedical Applications
- Computational Drug Discovery Methods
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Environmental Toxicology and Ecotoxicology
- Advanced biosensing and bioanalysis techniques
- Medicinal Plants and Neuroprotection
- Metal complexes synthesis and properties
- Pesticide Exposure and Toxicity
- Medicinal Plants and Bioactive Compounds
- Cholinesterase and Neurodegenerative Diseases
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Vitamin C and Antioxidants Research
- Cancer Cells and Metastasis
- Research on Leishmaniasis Studies
- Pluripotent Stem Cells Research
- Cancer-related Molecular Pathways
- Bioactive Compounds and Antitumor Agents
- GABA and Rice Research
University of Kalyani
2014-2025
Science Club
2024
Jawaharlal Nehru University
2016-2017
West Bengal State University
2016
Boiron (France)
2013
We isolated apigenin (5,7,4'-trihydroxy flavone) from ethanolic extract of Lycopodium clavatum (LC) used as a homeopathic mother tincture for treatment various diseases. assessed the anticancer potentials compound using human malignant melanoma cell line A375 and lung carcinoma A549 focussed on its putative molecular mechanism action apoptosis induction. examined cytotoxicity in both cancer cells normal peripheral blood mononuclear (PBMC). were more prone to apigenin-induced apoptosis,...
In this study, we examined the antioxidative and DNA protective potentials of apigenin, a flavonoid polyphenol isolated from Lycopodium clavatum, in both in-vitro (HaCaT skin keratinocytes) in-vivo (mice) models against UV-B radiation. We used DAPI staining UV-B-irradiated HaCaT keratinocytes pre-treated with without apigenin to assess damage. also flow-cytometric analysis mice exposed radiation or topical application assess, through comet assay, chromosomal aberrations quanta reactive...
Cancer is a disease that needs multi-faceted approach from different systems of medicine. The purpose this study was to evaluate whether homeopathically-potentized ultra-high dilutions Lycopodium Clavatum (LC-5C and LC-15C, respectively) have any anti-cancer effects on HeLa cells. Cells were exposed either LC-5C (diluted below Avogadro's limit, i.e., 10(-10)) or LC-15C beyond 10(-30)) (drug-treated) 30% succussed ethanol ("vehicle" the drug). drug-induced modulation in percent cell...
The pyridinium-based fluororeceptor 1 and the sensor bead 2 recognize hydrogen pyrophosphate effectively through 'Indicator Displacement Assay' (IDA) technique over a series of other anions in aq CH3CN (CH3CN/H2O = 4:1, v/v, pH 6.5). is also capable sensing same anion selectively pure water.
A new rhodamine-based bis-sulfonamide 1 has been designed and synthesized. The receptor selectively recognizes Cu2+ Hg2+ ions in CH3CN–water (4/1, v/v; 10 μM tris HCl buffer, pH 6.8) by showing different emission characteristics color changes. While is sensed through increase emission, detected a weak ratiometric change of 1. shows vitro detection both the human cervical cancer (HeLa) cells.
Abstract The present study predicts the molecular targets and druglike properties of phyto-compound piperine (PIP) by in silico studies including docking simulation, druglikeness prediction ADME analysis for prospective therapeutic benefits against diabetic complications. PIP was encapsulated biodegradable polymer poly-lactide-co-glycolide (PLGA) to form nanopiperine (NPIP) their physico-chemical were characterized AFM DLS. ∼ 30 nm sized NPIP showed 86.68% encapsulation efficiency − 6 mV...
The
A family of biologically active novel zinc(II) compounds, namely [Zn(ahpa)(Cl)(H2O)] (1), [Zn(ahpa)(NO3)(H2O)] (2) and [Zn(ahpa)(H2O)2](ClO4) (3) anthracene-appended multifunctional organic scaffold, Hahpa (Hahpa = 3-((anthracene-10-ylmethyl)(2-hydroxyethyl)amino)propanoic acid) were synthesized characterized....
Background: Bacteria resist drugs by employing new resistance mechanisms, leading to prolonged infection and complexity in therapeutic prognosis that concordantly decreases drug efficacy. In recent years, nanotechnology has gained immense popularity for the development of delivery systems combat global pharmaceutical crisis multi-drug resistance. Objective: The present work aimed focus on green chemistry-based synthesis silver nanoparticles (AgNPs) using phytocompound chlorophyllin form...
A new rhodamine appended tripodal receptor 1 has been designed and synthesized. The selectively recognizes Hg2+ ions in CH3CN–water (4 : 1, v/v; 10 μM tris HCl buffer, pH 7.0) by displaying a ratiometric change emission. Additionally, the visual detection is possible sharp color. shows vitro of human cervical cancer (HeLa) cells.
In South East Asia, groundwater arsenic contamination has become a great menace. Chronic intoxication leads to hyperglycemic condition in animals and man. Because of undesirable side-effects affordability, orthodox medicine, like insulin, is not preferred by many who natural products instead. Unfortunately, such mostly lack scientific validation. Therefore, we became interested assessing the efficacy ethanolic seed extract Syzygium jambolanum (SJ), traditionally used against diabetic...
Nano-encapsulation of several natural products has become an important tool in enhancing the bioavailability some modern drugs against many diseases. Pelargonidin is anthocyanidin found fruits and vegetables. loaded with poly-lactide-co-glycolic-acid, a non-toxic biodegradable polymer, to produce nano-pelargonidin. Size, morphology, zeta potential, planar uniformity formulated nano-pelargonidin were determined by atomic force microscopy dynamic light scattering. The time required for...