A5068455454- Parvovirus B19 Infection Studies
- Sepsis Diagnosis and Treatment
- Emergency and Acute Care Studies
- Artificial Intelligence in Healthcare and Education
- Antimicrobial Resistance in Staphylococcus
- Patient Satisfaction in Healthcare
- Clinical Reasoning and Diagnostic Skills
- Clostridium difficile and Clostridium perfringens research
- Antibiotic Use and Resistance
- Autoimmune and Inflammatory Disorders Research
- Heart Failure Treatment and Management
- Immune Cell Function and Interaction
- Genital Health and Disease
- Surgical site infection prevention
- Machine Learning in Healthcare
- Nosocomial Infections in ICU
- Chemotherapy-related skin toxicity
- Chronic Disease Management Strategies
- Hemodynamic Monitoring and Therapy
- Healthcare Policy and Management
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Frailty in Older Adults
- Streptococcal Infections and Treatments
- Clinical practice guidelines implementation
Beth Israel Deaconess Medical Center
2022-2024
University of Maryland, Baltimore
2018-2023
Harvard University
2021
Museum of Heilongjiang Province
2021
University of Maryland, College Park
2019
Johns Hopkins Medicine
2017
Johns Hopkins University
2017
This cross-sectional study assesses the ability of a large language model to process medical data and display clinical reasoning compared with attending physicians residents.
Abstract Background There are limited US data assessing adherence to surgical antimicrobial prophylaxis guidelines, particularly across a large, nationwide sample. Moreover, commonly prescribed inappropriate regimens remain unknown, hindering improvement initiatives. Methods We conducted retrospective cohort study of adults who underwent elective craniotomy, hip replacement, knee spinal procedure, or hernia repair in 2019–2020 at hospitals the PINC AI (Premier) Healthcare Database. evaluated...
Patients hospitalized with heart failure suffer the highest rates of 30-day readmission among other clinically defined patient populations in United States. Investigation into predictability readmissions can lead to clinical decision support tools and targeted interventions that help care providers improve individual reduce risk.This study aimed develop a dynamic risk prediction model yields daily predictions for patients toward identifying trajectories over time predictors associated...
Performance of large language models (LLMs) on medical tasks has traditionally been evaluated using multiple choice question benchmarks. However, such benchmarks are highly constrained, saturated with repeated impressive performance by LLMs, and have an unclear relationship to in real clinical scenarios. Clinical reasoning, the process which physicians employ critical thinking gather synthesize data diagnose manage problems, remains attractive benchmark for model performance. Prior LLMs...
Background: Inappropriate antibiotic prescription leads to increased Clostridiodes difficile infections, adverse effects including organ toxicity, and generation of antibiotic-resistant bacteria. Despite efforts improve use in acute-care settings, unnecessary inappropriate still occur 30%–50% patients. Objectives: We assessed factors associated with at 2 time points: (1) initial, empiric therapy (2) 3–5 days after initiation. Methods: As part a multicenter study investigating strategies...
Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome of inappropriate immune activation which can present at any age and commonly associated with other conditions either excessive or impaired response, such as malignancy, infection, autoimmunity immunodeficiency. In cases human immunodeficiency virus (HIV) an additional trigger acute infection malignancy frequently identified. We report case HLH presenting in patient uncontrolled HIV reactivated hepatitis B to our knowledge...
To the Editor—We thank Lim et al for their interest in our work evaluating adherence to surgical antimicrobial prophylaxis guidelines [1]. In correspondence, raise issue that study used ICD-10-CM codes and other claims data identify patients colonized with or at high risk methicillin-resistant Staphylococcus aureus (MRSA), citing lack of validation these purposes, propose studies using types should include a sample. We agree questions validity variable performance are critically important....
Abstract Background Hospital-onset C. difficile infection (HO-CDI) rates are publicly reported. However, patient-level risk factors not included in the current adjustment methodology, and knowledge as to which include is incomplete. This study aimed determine whether electronically-available comorbidities laboratory indicators of severity illness for HO-CDI. Methods We performed a retrospective cohort all adult patients admitted three hospitals (one academic, two community) Baltimore,...
<sec> <title>BACKGROUND</title> Patients hospitalized with heart failure suffer the highest rates of 30-day readmission among any clinically-defined patient populations in United States. Investigation into predictability readmissions can lead to clinical decision-support tools and targeted interventions that help care providers improve individual reduce risk. </sec> <title>OBJECTIVE</title> We developed a dynamic risk prediction model yields daily predictions for patients toward identifying...
Abstract Objective: To determine whether electronically available comorbidities and laboratory values on admission are risk factors for hospital-onset Clostridioides difficile infection (HO-CDI) across multiple institutions they could be used to improve adjustment. Patients: All patients at least 18 years of age admitted 3 hospitals in Maryland between January 1, 2016, 2018. Methods: Comorbid conditions were assigned using the Elixhauser comorbidity index. Multivariable log-binomial...
Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome of inappropriate immune activation which can present at any age and commonly associated with other conditions either excessive or impaired response, such as malignancy, infection, autoimmunity immunodeficiency. In cases human immunodeficiency virus (HIV) an additional trigger acute infection malignancy frequently identified. We report case HLH presenting in patient uncontrolled HIV reactivated hepatitis B to our knowledge...
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