Matthew B. Crist

ORCID: 0000-0001-5277-0371
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About
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Research Areas
  • Mycobacterium research and diagnosis
  • Nosocomial Infections in ICU
  • Infection Control in Healthcare
  • Antibiotic Use and Resistance
  • Tuberculosis Research and Epidemiology
  • Disaster Response and Management
  • Antimicrobial Resistance in Staphylococcus
  • Public Health Policies and Education
  • Infections and bacterial resistance
  • Pneumonia and Respiratory Infections
  • Streptococcal Infections and Treatments
  • Medical Malpractice and Liability Issues
  • Emergency and Acute Care Studies
  • Viral Infections and Outbreaks Research
  • SARS-CoV-2 detection and testing
  • Plant Pathogenic Bacteria Studies
  • Antibiotic Resistance in Bacteria
  • Otolaryngology and Infectious Diseases
  • Veterinary medicine and infectious diseases
  • Cystic Fibrosis Research Advances
  • Intravenous Infusion Technology and Safety
  • Bacterial Identification and Susceptibility Testing
  • COVID-19 and Mental Health
  • Safe Handling of Antineoplastic Drugs
  • Patient Satisfaction in Healthcare

National Center for Emerging and Zoonotic Infectious Diseases
2017-2024

Centers for Disease Control and Prevention
2007-2022

The Centers
2022

Federal Reserve
2022

New York Proton Center
2022

Communities In Schools of Orange County
2022

Manhattan Institute for Policy Research
2022

Oregon Medical Research Center
2022

Lindsay Unified School District
2022

University of Pittsburgh
2022

Abstract The purpose of this document is to highlight practical recommendations assist acute care hospitals prioritize and implement strategies prevent ventilator-associated pneumonia (VAP), events (VAE), non-ventilator hospital-acquired (NV-HAP) in adults, children, neonates. This updates the Strategies Prevent Ventilator-Associated Pneumonia Acute Care Hospitals published 2014. expert guidance sponsored by Society for Healthcare Epidemiology (SHEA), product a collaborative effort led SHEA,...

10.1017/ice.2022.88 article EN cc-by Infection Control and Hospital Epidemiology 2022-05-20

Abstract An atypically large outbreak of Elizabethkingia anophelis infections occurred in Wisconsin. Here we show that it was caused by a single strain with thirteen characteristic genomic regions. Strikingly, the isolates an accelerated evolutionary rate and atypical mutational spectrum. Six phylogenetic sub-clusters distinctive temporal geographic dynamics are revealed, their last common ancestor existed approximately one year before first recognized human infection. Unlike other E. , had...

10.1038/ncomms15483 article EN cc-by Nature Communications 2017-05-24

In the spring of 2015, investigators in Switzerland reported a cluster six patients with invasive infection Mycobacterium chimaera, species nontuberculous mycobacterium ubiquitous soil and water. The infected had undergone open-heart surgery that used contaminated heater-cooler devices during extracorporeal circulation (1). July Pennsylvania hospital also identified mycobacterial infections among patients. Similar to Swiss report, field investigation by Department Health, assistance from...

10.15585/mmwr.mm6540a6 article EN MMWR Morbidity and Mortality Weekly Report 2016-10-13

Clonal VGII subtypes (outbreak strains) of Cryptococcus gattii have caused an outbreak in the US Pacific Northwest since 2004. Outbreak-associated infections occur equally male and female patients (median age 56 years) usually cause pulmonary disease persons with underlying medical conditions. Since 2009, a total 25 C. infections, 23 (92%) by non-outbreak strain gattii, been reported from 8 non-Pacific states. Sixteen (64%) were previously healthy, 21 (84%) male; median was 43 years (range...

10.3201/eid1910.130441 article EN cc-by Emerging infectious diseases 2013-10-01

Executive Summary In 2020 a group of U.S. healthcare leaders formed the National Organization to Prevent Hospital-Acquired Pneumonia (NOHAP) issue call action address non–ventilator-associated hospital-acquired pneumonia (NVHAP). NVHAP is one most common and morbid healthcare-associated infections, but it not tracked, reported, or actively prevented by hospitals. This national includes (1) launching conversation about prevention; (2) adding prevention measures education for patients,...

10.1017/ice.2021.239 article EN Infection Control and Hospital Epidemiology 2021-06-09

Abstract A surgical heater–cooler unit has been implicated as the source for Mycobacterium chimaera infections among cardiac surgery patients in several countries. We isolated M. from units and patient United States. Whole-genome sequencing corroborated a risk these acting reservoir this pathogen.

10.3201/eid2503.181282 article EN cc-by Emerging infectious diseases 2019-02-05

Background. Group A Streptococcus (GAS) is an important bacterial cause of life-threatening illness among the elderly. Public health officials investigated a protracted GAS outbreak in skilled nursing facility Georgia housing patients requiring 24-hour or rehabilitation, to prevent additional cases. Methods. We defined case as resident with onset after January 2009 isolated from usually sterile (invasive) nonsterile site (noninvasive). Cases were "recurrent" if >1 month elapsed between...

10.1093/cid/cit558 article EN public-domain Clinical Infectious Diseases 2013-09-09

Nontuberculous mycobacteria (NTM), ubiquitous in soil and water, usually infect immunocompromised persons. However, even healthy persons are susceptible to infection through percutaneous inoculation. Although 77% of NTM diseases manifest as primarily pulmonary illnesses (1), also skin, bones, joints, the lymphatic system, soft tissue. infections can have incubation periods that exceed 5 years (2), often require prolonged treatment, lead sepsis death. Extrapulmonary outbreaks been reported...

10.15585/mmwr.mm6731a3 article EN MMWR Morbidity and Mortality Weekly Report 2018-08-09

Burkholderia cepacia complex (Bcc) has caused healthcare-associated outbreaks, often in association with contaminated products. The identification of 4 Bcc bloodstream infections patients residing at a single skilled nursing facility (SNF) within 1 week led to an epidemiological investigation identify additional cases and the outbreak source.A case was initially defined via blood culture yielding SNF resident receiving intravenous therapy after August 2016. Multistate notifications were...

10.1093/cid/ciy910 article EN Clinical Infectious Diseases 2018-10-18

Objectives. To assess SARS-CoV-2 transmission within a correctional facility and recommend mitigation strategies.Methods. From April 29 to May 15, 2020, we established the point prevalence of COVID-19 among incarcerated persons staff in Arkansas. Participants provided respiratory specimens for testing completed questionnaires on symptoms factors associated with transmission.Results. Of 1647 128 tested, 30.5% (range by housing unit = 0.0%-58.2%) 2.3% tested positive SARS-CoV-2. Among those...

10.2105/ajph.2020.306117 article EN American Journal of Public Health 2021-03-18

F₂-isoprostanes (F₂-IsoP) are oxidant stress biomarkers that higher in HIV-infected women than men. We explored whether the effect of hemoglobin (Hgb), serum iron, or anemia on F₂-IsoP is different between and

10.1097/qai.0b013e3182a60f36 article EN JAIDS Journal of Acquired Immune Deficiency Syndromes 2013-08-01

Abstract In March 2018, the US Food and Drug Administration (FDA), Centers for Disease Control Prevention, California Department of Public Health, Los Angeles County Health Pennsylvania initiated an investigation outbreak Burkholderia cepacia complex ( Bcc ) infections. Sixty infections were identified in California, New Jersey, Pennsylvania, Maine, Nevada Ohio. The linked to a no-rinse cleansing foam product (NRCFP), produced by Manufacturer A, used skin care patients healthcare settings....

10.1017/s0950268822000668 article EN cc-by-nc-nd Epidemiology and Infection 2022-01-01

In 2015, an international outbreak of Mycobacterium chimaera infections among patients undergoing cardiothoracic surgeries was associated with exposure to contaminated LivaNova 3T heater-cooler devices (HCDs). From June 2017 October 2020, the Centers for Disease Control and Prevention notified 18 M. who had undergone at 2 hospitals in Kansas (14 patients) California (4 patients); 17 HCDs. Whole-genome sequencing clinical environmental isolates matched global strain identified...

10.1017/ice.2021.396 article EN Infection Control and Hospital Epidemiology 2021-10-06

Between April 2020 and May 2021, the Centers for Disease Control Prevention (CDC) awarded more than $40 billion to health departments nationwide COVID-19 prevention response activities. One of identified priorities this investment was improving infection control (IPC) in nursing homes.CDC developed a virtual course train new less experienced public staff core healthcare IPC principles application CDC guidance homes.From October August led training sessions 12 cohorts using pretraining...

10.1097/phh.0000000000001600 article EN Journal of Public Health Management and Practice 2022-09-08

Context: The Centers for Disease Control and Prevention awarded $85 million to health care–associated infection antibiotic resistance (HAI/AR) programs in March 2015 as part of Infection Assessment Response (ICAR) activities the Epidemiology Laboratory Capacity cooperative agreement Domestic Ebola Supplement. Program: One goal this funding was assess improve program capacity respond potential care outbreaks (eg, HAI clusters). All 55 funded (in 49 state 6 local departments) participated....

10.1097/phh.0000000000001148 article EN Journal of Public Health Management and Practice 2020-04-17

Abstract Background In July 2018, the Arkansas Department of Health (ADH) was notified by hospital A 3 patients with bloodstream infections (BSIs) a rapidly growing nontuberculous Mycobacterium (NTM) species; on 5 September 6 additional BSIs were reported. All among oncology at clinic A. We investigated to identify sources and prevent further infections. Methods ADH performed an onsite investigation 7 2018 reviewed patient charts, obtained environmental samples, cultured isolates. The...

10.1093/cid/ciz1120 article EN Clinical Infectious Diseases 2019-11-12

One in six nursing home residents and staff with positive SARS-CoV-2 tests ≥90 days after initial infection had specimen cycle thresholds (Ct) <30. Individuals Ct<30 were more likely to report symptoms but not different from individuals high Ct value specimens by other clinical testing data.

10.1017/ice.2022.62 article EN Infection Control and Hospital Epidemiology 2022-05-20

Abstract Background Elizabethkingia (EK) are non-motile gram-negative rods found in soil and water an emerging cause of healthcare-associated infections (HAIs). We describe Centers for Disease Control Prevention (CDC) consultations EK outbreaks. Methods CDC maintains records with state or local health departments related to HAI outbreaks infection control breaches. reviewed involving species as the primary pathogen concern January 1, 2013 December 31, 2019 summarized data on healthcare...

10.1093/ofid/ofaa439.1057 article EN cc-by-nc-nd Open Forum Infectious Diseases 2020-10-01
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