A5078493598- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Streptococcal Infections and Treatments
- Central Venous Catheters and Hemodialysis
- Infective Endocarditis Diagnosis and Management
- Urinary Tract Infections Management
- Clostridium difficile and Clostridium perfringens research
- Nosocomial Infections in ICU
- Opioid Use Disorder Treatment
- Neutropenia and Cancer Infections
- HIV, Drug Use, Sexual Risk
- Bacterial biofilms and quorum sensing
- Heparin-Induced Thrombocytopenia and Thrombosis
- Geriatric Care and Nursing Homes
- Mycobacterium research and diagnosis
- Pediatric Urology and Nephrology Studies
- COVID-19 and healthcare impacts
- Platelet Disorders and Treatments
- Infection Control in Healthcare
- Intramuscular injections and effects
- Enterobacteriaceae and Cronobacter Research
- Helicobacter pylori-related gastroenterology studies
- Plant Pathogenic Bacteria Studies
Centers for Disease Control and Prevention
2016-2025
National Center for Emerging and Zoonotic Infectious Diseases
2019-2024
CDC Foundation
2019-2023
United States Public Health Service Commissioned Officers Association
2022
United States Public Health Service
2021
The Centers
2020
Minnesota Department of Health
2015-2018
Engineering Associates (United States)
2015-2018
Epidemic Intelligence Service
2013-2016
Center for Surveillance, Epidemiology, and Laboratory Services
2016
Staphylococcus aureus is one of the most common pathogens in health care facilities and community, can cause invasive infections, sepsis, death. Despite progress preventing methicillin-resistant S. (MRSA) infections settings, assessment problem both community settings needed. Further, epidemiology methicillin-susceptible (MSSA) not well described at national level.Data from Emerging Infections Program (EIP) MRSA population surveillance (2005-2016) Premier Cerner Electronic Health Record...
Abstract Objective: Describe common pathogens and antimicrobial resistance patterns for healthcare-associated infections (HAIs) that occurred during 2015–2017 were reported to the Centers Disease Control Prevention’s (CDC’s) National Healthcare Safety Network (NHSN). Methods: Data from central line-associated bloodstream (CLABSIs), catheter-associated urinary tract (CAUTIs), ventilator-associated events (VAEs), surgical site (SSIs) acute-care hospitals, long-term inpatient rehabilitation...
Cerebral venous sinus thrombosis (CVST) with thrombocytopenia, a rare and serious condition, has been described in Europe following receipt of the ChAdOx1 nCoV-19 vaccine (Oxford/AstraZeneca), which uses chimpanzee adenoviral vector. A mechanism similar to autoimmune heparin-induced thrombocytopenia (HIT) proposed. In US, Ad26.COV2.S COVID-19 (Janssen/Johnson & Johnson), human vector, received Emergency Use Authorization (EUA) on February 27, 2021. By April 12, 2021, approximately 7 million...
Thrombosis with thrombocytopenia syndrome (TTS) is a potentially life-threatening condition associated adenoviral-vectored COVID-19 vaccination. It presents similarly to spontaneous heparin-induced thrombocytopenia. Twelve cases of cerebral venous sinus thrombosis after vaccination the Ad26.COV2.S vaccine (Janssen/Johnson & Johnson) have previously been described.To describe surveillance data and reporting rates all reported TTS in United States.Case series.United patients receiving from 14...
On February 27, 2021, the Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for adenovirus-vectored COVID-19 vaccine (Janssen Biotech, Inc., a Janssen Pharmaceutical company, Johnson & Johnson), on 28, Advisory Committee Immunization Practices (ACIP) interim recommendation its use as single-dose primary vaccination in persons aged ≥18 years (1,2). April 13, CDC FDA recommended pause of after reports thrombosis with thrombocytopenia syndrome (TTS), rare condition...
After controlling for patient risk factors and healthcare exposures, NAP1 Clostridium difficile strain type was associated with severe disease, outcome, 14-day mortality in multivariate models compared other types.
OBJECTIVE To describe pathogen distribution and antimicrobial resistance patterns for healthcare-associated infections (HAIs) reported to the National Healthcare Safety Network (NHSN) from pediatric locations during 2011–2014. METHODS Device-associated infection data were analyzed central line-associated bloodstream (CLABSI), catheter-associated urinary tract (CAUTI), ventilator-associated pneumonia (VAP), surgical site (SSI). Pooled mean percentage was calculated a variety of...
In the United States, age-adjusted opioid overdose death rates increased by >200% during 1999-2015, and heroin nearly 300% 2011-2015 (1). During 2011-2013, rate of use within past year among U.S. residents aged ≥12 years 62.5% overall 114.3% non-Hispanic whites, compared with 2002-2004 (2). Increases in human immunodeficiency virus (HIV) hepatitis C (HCV) infections related to increases injection drug have been recently highlighted (3,4); likewise, invasive bacterial infections, including...
Abstract Background Rises in the incidence of bacterial infections, such as infective endocarditis (IE), have been reported conjunction with opioid crisis. However, recent trends for IE and other serious infections among persons substance use disorders (SUDs) are unknown. Methods Using Premier Healthcare Database, we identified hospitalizations from 2012 through 2017 adults primary discharge diagnoses secondary SUD diagnoses, using International Classification Diseases, Clinical Modification...
Abstract Objective: To describe common pathogens and antimicrobial resistance patterns for healthcare-associated infections (HAIs) among pediatric patients that occurred in 2015–2017 were reported to the Centers Disease Control Prevention’s National Healthcare Safety Network (NHSN). Methods: Antimicrobial data analyzed implicated central line-associated bloodstream (CLABSIs), catheter-associated urinary tract (CAUTIs), ventilator-associated pneumonias (VAPs), surgical site (SSIs). This...
Racial and ethnic minorities are disproportionately affected by end-stage kidney disease (ESKD). ESKD patients on dialysis at increased risk for Staphylococcus aureus bloodstream infections, but racial, ethnic, socioeconomic disparities associated with this outcome not well described.Surveillance data from the 2020 National Healthcare Safety Network (NHSN) 2017-2020 Emerging Infections Program (EIP) were used to describe infections among hemodialysis (hemodialysis patients) linked...
To assess challenges to implementation of a new National Healthcare Safety Network (NHSN) surveillance definition, mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI).Multicenter field test.Selected locations acute care hospitals participating in NHSN central line-associated (CLABSI) surveillance.Hospital staff augmented their CLABSI for 2 months incorporate MBI-LCBI: primary due selected group organisms patients with either neutropenia or an allogeneic hematopoietic...
Invasive community-associated methicillin-resistant Staphylococcus aureus (MRSA) incidence in the United States is higher among black persons than white persons. We explored extent to which socioeconomic factors might explain this racial disparity. A retrospective cohort was based on Centers for Disease Control and Prevention’s Emerging Infections Program surveillance data invasive MRSA cases (isolated from a normally sterile site of an outpatient or hospital admission day ≤3 patient without...
Recent antimicrobial resistance data are lacking from inpatient oncology settings to guide infection prophylaxis and treatment recommendations. We describe central line-associated bloodstream (CLABSI) pathogens patterns reported locations the Centers for Disease Control Prevention's National Healthcare Safety Network (NHSN).CLABSI NHSN 2009 2012 adult were compared nononcology within same hospitals. Pathogen profile, rates, CLABSI incidence rates per 1000 line-days calculated. using Poisson...
Nursing homes are high-risk settings for outbreaks of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) (1,2). During COVID-19 pandemic, U.S. health departments worked to improve infection prevention and control (IPC) practices in nursing prevent limit spread affected facilities; however, limited resources have hampered departments' ability rapidly provide IPC support all within their jurisdictions. Since 2008, Centers Medicare & Medicaid Services (CMS) has published...
During 2014-2017, CDC Emerging Infections Program surveillance data reported that the occurrence of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections associated with injection drug use doubled among persons aged 18-49 years residing in Monroe County western New York.*Unpublished also indicate an increasing proportion all Candida spp.bloodstream and group A Streptococcus (GAS) 15 York counties are occurring who inject drugs.In addition, across six sites nationwide, MRSA...
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the vulnerability of residents and staff members in long-term care facilities (LTCFs) (1).Although skilled nursing (SNFs) certified by Centers for Medicare & Medicaid Services (CMS) have federal COVID-19 reporting requirements, national surveillance data are less readily available other types LTCFs, such as assisted living (ALFs) those providing similar residential care.However, many state territorial health departments...
Identifying asymptomatic individuals early through serial testing is recommended to control coronavirus disease 2019 (COVID-19) in nursing homes, both response an outbreak ("outbreak testing" of residents and healthcare personnel) facilities without outbreaks ("nonoutbreak personnel). The effectiveness isolation with or nonoutbreak was evaluated.Using published SARS-CoV-2 transmission parameters, the fraction transmissions prevented (weekly, every 3 days, daily) persons compared...
Abstract Background Nursing home residents experience a large burden of invasive methicillin‐resistant Staphylococcus aureus (MRSA) infections. Data are limited regarding nursing characteristics associated with differences in facility‐level MRSA rates. Methods We analyzed 2011–2015 data from CDC's Emerging Infections Program (EIP) active population‐ and laboratory‐based surveillance for cases within seven states. A home‐onset case was defined as cultured normally sterile site person living 3...
Abstract Background During 2005–2010, incidence of community-associated (CA) invasive methicillin-resistant Staphylococcus aureus (MRSA) infections among children was rising, whereas hospital-onset (HO) rates were unchanged except for a decline young infants. Recent trends in MRSA have not been described.Figure 1.Epidemiologic classification cases Methods We analyzed aged < 18 years reported during 2011–2021 through active population- and laboratory-based surveillance by CDC's...
Abstract Background Disseminated Mycobacterium avium complex (MAC) infection rates have declined in persons with HIV; some studies report increasing numbers of disseminated nontuberculous mycobacteria (NTM) infections other groups immunocompromised persons. However, no consensus definition exists for NTM these populations. We compared characteristics without AIDS using different epidemiologic definitions.Table 1.Disseminated definitions.. Methods CDC’s Emerging Infections Program conducted...
Background— Recent data on digoxin prescribing and adverse events are lacking but could help inform the management of in contemporary heart failure treatment. Methods Results— We determined nationally representative numbers rates emergency department (ED) visits for toxicity United States using 2005 to 2010 reports from National Electronic Injury Surveillance System–Cooperative Adverse Drug Event project Ambulatory (and Hospital Ambulatory) Medical Care Surveys. Based 441 cases, an estimated...
Despite substantial attention to the individual topics, little is known about relationship between racial disparities and antimicrobial-resistant and/or healthcare-associated infection trends, such as for methicillin-resistant Staphylococcus aureus (MRSA).