A5015665164- SARS-CoV-2 and COVID-19 Research
- Clostridium difficile and Clostridium perfringens research
- Vaccine Coverage and Hesitancy
- Virology and Viral Diseases
- Nosocomial Infections in ICU
- Microscopic Colitis
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Infection Control and Ventilation
- COVID-19 and healthcare impacts
- Viral gastroenteritis research and epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 and Mental Health
- Influenza Virus Research Studies
- Syphilis Diagnosis and Treatment
- Animal Disease Management and Epidemiology
- Drug-Induced Adverse Reactions
- Legionella and Acanthamoeba research
- Rabies epidemiology and control
- Immune responses and vaccinations
- Biosensors and Analytical Detection
- Reproductive tract infections research
Centers for Disease Control and Prevention
2016-2025
National Center for Emerging and Zoonotic Infectious Diseases
2017-2024
Saint Luke's Health System
2021
Computer Emergency Response Team
2021
Regional Health
2021
Action Network
2021
Biology of Infection
2008-2019
Engineering Associates (United States)
2017-2019
The Centers
2018
American Veterinary Medical Association
2017
Messenger RNA (mRNA) BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) COVID-19 vaccines have been shown to be effective in preventing symptomatic randomized placebo-controlled Phase III trials (1,2); however, the benefits of these for asymptomatic SARS-CoV-2 (the virus that causes COVID-19) infection, particularly when administered real-world conditions, is less well understood. Using prospective cohorts health care personnel, first responders, other essential frontline workers* eight U.S....
Background. The epidemiology of Clostridium difficile -associated disease (CDAD) is changing, with evidence increased incidence and severity. However, the understanding magnitude reasons for this change currently hampered by lack standardized surveillance methods. Objective Methods. An ad hoc C. working group was formed to develop interim definitions recommendations based on existing literature expert opinion that can help improve CDAD prevention efforts. Definitions Recommendations. A case...
Information is limited regarding the effectiveness of two-dose messenger RNA (mRNA) vaccines BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) in preventing infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) attenuating disease 2019 (Covid-19) when administered real-world conditions.
Advances in water management and sanitation have substantially reduced waterborne disease the United States, although outbreaks continue to occur. Public health agencies U.S. states territories* report information on CDC Waterborne Disease Outbreak Surveillance System (http://www.cdc.gov/healthywater/surveillance/index.html). For 2011-2012, 32 drinking water-associated were reported, accounting for at least 431 cases of illness, 102 hospitalizations, 14 deaths. Legionella was responsible 66%...
The epidemiology of Mycoplasma pneumoniae (Mp) among US children (<18 years) hospitalized with community-acquired pneumonia (CAP) is poorly understood.In the Etiology Pneumonia in Community study, we prospectively enrolled 2254 radiographically confirmed from January 2010-June 2012 and tested nasopharyngeal/oropharyngeal swabs for Mp using real-time polymerase chain reaction (PCR). Clinical epidemiological features PCR-positive -negative were compared logistic regression. Macrolide...
Psittacosis, also known as parrot fever and ornithosis, is a bacterial infection that can cause severe pneumonia other serious health problems in humans. It caused by Chlamydia psittaci. Reclassification of the order Chlamydiales 1999 into 2 genera (Chlamydia Chlamydophila) was not wholly accepted or adopted. This resulted reversion to single, original genus Chlamydia, which now encompasses all 9 species including During 2003-2014, 112 human cases psittacosis were reported Centers for...
We determined estimated incidence of and risk factors for community-associated Clostridium difficile infection (CA-CDI) among patients treated at 6 North Carolina hospitals. CA-CDI case-patients were defined as adults (>18 years age) with a positive stool test result C. toxin no hospitalization within the prior 8 weeks. was 21 46 per 100,000 person-years in Veterans Affairs (VA) outpatients Durham County populations, respectively. VA more likely than controls to have received antimicrobial...
Background. On 12 February 2008, an infected Swiss traveler visited hospital A in Tucson, Arizona, and initiated a predominantly health care–associated measles outbreak involving 14 cases. We investigated risk factors that might have contributed to transmission assessed outbreak-associated costs.
To address high COVID-19 burden in U.S. nursing homes, rapid SARS-CoV-2 antigen tests have been widely distributed those facilities. However, performance data are lacking, especially asymptomatic people.
Racial and ethnic minorities are disproportionately affected by end-stage kidney disease (ESKD). ESKD patients on dialysis at increased risk for Staphylococcus aureus bloodstream infections, but racial, ethnic, socioeconomic disparities associated with this outcome not well described.Surveillance data from the 2020 National Healthcare Safety Network (NHSN) 2017-2020 Emerging Infections Program (EIP) were used to describe infections among hemodialysis (hemodialysis patients) linked...
In late April 2009, the first documented 2009 pandemic influenza A (pH1N1) virus infection outbreak in a university setting occurred Delaware, with large numbers of students presenting respiratory illness. At time this investigation, little was known about severity illness, effectiveness vaccine, or transmission factors pH1N1 infection. We characterized determined impact outbreak, and examined associated transmission.Health clinic records were reviewed. An online survey administered to all...
Despite high 2-dose measles-mumps-rubella (MMR) vaccine coverage, a large mumps outbreak occurred on the US Territory of Guam during 2009 to 2010, primarily in school-aged children.We implemented active surveillance April 2010 peak and characterized epidemiology. We administered third doses MMR eligible students aged 9-14 years 7 schools with highest attack rates (ARs) between May 18, 21, 2010. Baseline surveys, follow-up surveys case-reports were used determine ARs. Adverse events...
During 2009-2010, a northeastern US religious community experienced large mumps outbreak despite high 2-dose measles-mumps-rubella (MMR) vaccine coverage. A third dose of MMR was offered to students in an affected effort control the outbreak.Eligible sixth- 12th-grade 3 schools were vaccine. Baseline and follow-up surveys physician case reports used monitor attack rates (ARs). We calculated ARs for defined 3-week periods before after intervention.Of 2265 eligible students, 2178 (96.2%)...
BACKGROUND: Stevens-Johnson syndrome (SJS) is an uncommon, sporadic disease and outbreaks are rare. In November 2013, outbreak of SJS was identified at Children’s Hospital Colorado. METHODS: Outbreak cases were children aged 5–21 with a discharge diagnosis admitted from September 1 to 30, 2013. Medical charts reviewed using standardized data collection forms. Respiratory specimens tested for viruses Mycoplasma pneumoniae (Mp) by polymerase chain reaction (PCR). We conducted separate 4-year...
The Arizona Healthcare, Emergency Response, and Other Essential workers Study (AZ HEROES) aims to examine the epidemiology of SARS-CoV-2 infection COVID-19 illness among adults with high occupational exposure risk.
The BNT162b2 (Pfizer-BioNTech) mRNA COVID-19 vaccine has demonstrated high efficacy in preventing infection with SARS-CoV-2 (the virus that causes COVID-19) randomized placebo-controlled Phase III trials persons aged 12-17 years (referred to as adolescents this report) (1); however, data on real-word effectiveness (VE) among are limited (1-3). As of December 2021, the Pfizer-BioNTech is approved by Food and Drug Administration (FDA) for 16-17 under FDA emergency use authorization those 12-15...
Importance Data on the epidemiology of mild to moderately severe COVID-19 are needed inform public health guidance. Objective To evaluate associations between 2 or 3 doses mRNA vaccine and attenuation symptoms viral RNA load across SARS-CoV-2 lineages. Design, Setting, Participants A prospective cohort study essential frontline workers in Arizona, Florida, Minnesota, Oregon, Texas, Utah with infection confirmed by reverse transcriptase–polymerase chain reaction testing lineage classified...
Abstract Background. Mycoplasma pneumoniae is a common cause of community-acquired pneumonia (CAP). The molecular characteristics M detected in patients hospitalized with CAP the United States are poorly described. Methods. We performed characterization nasopharyngeal/oropharyngeal swabs from children and adults Centers for Disease Control Prevention Etiology Pneumonia Community (EPIC) study, including P1 typing, multilocus variable-number tandem-repeat analysis (MLVA), macrolide...
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the vulnerability of residents and staff members in long-term care facilities (LTCFs) (1).Although skilled nursing (SNFs) certified by Centers for Medicare & Medicaid Services (CMS) have federal COVID-19 reporting requirements, national surveillance data are less readily available other types LTCFs, such as assisted living (ALFs) those providing similar residential care.However, many state territorial health departments...
Abstract Background Limited information is available on the natural history of Clostridioides difficile colonization and infection in patients with new acquisition C. healthcare settings. Methods In 3 hospitals affiliated long-term care facilities, we collected serial perirectal cultures from no diarrhea enrollment to identify toxigenic carriage determined duration burden carriage. Asymptomatic was defined as transient if only 1 culture positive, negative before after, or persistent 2 more...
Importance Despite modest reductions in the incidence of hospital-onset Clostridioides difficile infection (HO-CDI), CDI remains a leading cause health care–associated infection. As no single intervention has proven highly effective on its own, multifaceted approach to controlling HO-CDI is needed. Objective To assess effectiveness Centers for Disease Control and Prevention’s Strategies Prevent Infection Acute Care Facilities Framework (hereafter, Framework) reducing incidence. Design,...