- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Pneumonia and Respiratory Infections
- Bacteriophages and microbial interactions
- Pneumocystis jirovecii pneumonia detection and treatment
- Listeria monocytogenes in Food Safety
- Enterobacteriaceae and Cronobacter Research
- Drug-Induced Adverse Reactions
- Antibiotic Use and Resistance
- Travel-related health issues
- Legionella and Acanthamoeba research
- Respiratory viral infections research
- Genomics and Phylogenetic Studies
- Food Safety and Hygiene
- Vaccine Coverage and Hesitancy
- Pharmaceutical and Antibiotic Environmental Impacts
- Zoonotic diseases and public health
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Urinary Tract Infections Management
- Bacterial biofilms and quorum sensing
Centers for Disease Control and Prevention
2016-2025
Waterborne Environmental (United States)
2016-2025
National Center for Emerging and Zoonotic Infectious Diseases
2016-2024
United States Department of Health and Human Services
2023
Epidemic Intelligence Service
2015-2021
Westmead Institute for Medical Research
2020
Westmead Hospital
2020
National Center for Immunization and Respiratory Diseases
2019
United States Food and Drug Administration
2018
Georgia Department of Agriculture
2018
As of April 30, 2021, approximately 101 million people in the U.S. had been fully vaccinated against COVID-19. Almost 10,300 COVID-19 vaccine breakthrough infections were reported from 46 states and territories. Vaccine occur only a small fraction all people.
Group B Streptococcus (GBS) is an important cause of invasive bacterial disease. Previous studies have shown a substantial and increasing burden GBS infections among nonpregnant adults, particularly older adults those with underlying medical conditions.
Extended-spectrum β-lactamases (ESBLs) confer resistance to clinically important third-generation cephalosporins, which are often used treat invasive salmonellosis. In the United States, ESBLs rarely found in Salmonella. However, 2014, US Food and Drug Administration bla
Abstract Background Produce-associated outbreaks of Shiga toxin–producing Escherichia coli (STEC) were first identified in 1991. In April 2018, New Jersey and Pennsylvania officials reported a cluster STEC O157 infections associated with multiple locations restaurant chain. The Centers for Disease Control Prevention (CDC) queried PulseNet, the national laboratory network foodborne disease surveillance, additional cases began investigation. Methods A case was defined as an infection between...
The Centers for Disease Control and Prevention (CDC) has identified nontyphoidal Salmonella as one of the top five pathogens contributing to foodborne illnesses in United States. Beef continues be a common source outbreaks, despite implementation interventions at slaughter processing facilities reduce contamination beef. We described outbreaks linked beef States during 2012–2019, examined trends, potential targets intervention prevention strategies. queried CDC's Foodborne Outbreak...
BACKGROUND: Stevens-Johnson syndrome (SJS) is an uncommon, sporadic disease and outbreaks are rare. In November 2013, outbreak of SJS was identified at Children’s Hospital Colorado. METHODS: Outbreak cases were children aged 5–21 with a discharge diagnosis admitted from September 1 to 30, 2013. Medical charts reviewed using standardized data collection forms. Respiratory specimens tested for viruses Mycoplasma pneumoniae (Mp) by polymerase chain reaction (PCR). We conducted separate 4-year...
Campylobacter causes an estimated 1.3 million diarrheal illnesses in the United States annually (1). In August 2017, Florida Department of Health notified CDC six jejuni infections linked to company A, a national pet store chain based Ohio. examined whole-genome sequencing (WGS) data and identified isolates from A puppies that were highly related isolate customer This information prompted multistate investigation by local state health agriculture departments identify outbreak source prevent...
Ceftriaxone-resistant Salmonella enterica serotype Typhi (Typhi), the bacterium that causes typhoid fever, is a growing public health threat. Extensively drug-resistant (XDR) resistant to ceftriaxone and other antibiotics used for treatment, including ampicillin, chloramphenicol, ciprofloxacin, trimethoprim-sulfamethoxazole (1). In March 2018, CDC began enhanced surveillance ceftriaxone-resistant in response an ongoing outbreak of XDR fever Pakistan. had previously reported first five cases...
More than 7.15 million cases of domestically acquired infectious waterborne illnesses occurred in the United States 2014, causing 120,000 hospitalizations and 6,600 deaths. We estimated disease incidence for 17 pathogens according to recreational, drinking, nonrecreational nondrinking (NRND) water exposure routes by using previously published estimates. In a total 5.61 (95% credible interval [CrI] 2.97-9.00 million) were linked recreational water, 1.13 CrI 255,000-3.54 drinking 407,000...
In September 2018, CDC identified Salmonella enterica serotype Newport (Newport) infections that were multidrug resistant (MDR), with decreased susceptibility to azithromycin, a recommended oral treatment agent. Until 2017, azithromycin had occurred in fewer than 0.5% of isolates from U.S. residents. This report summarizes the investigation multistate MDR outbreak conducted by CDC, state and local health departments, Department Agriculture's Food Safety Inspection Service. During June...
In August 2016, the Wisconsin Department of Health Services notified U.S. Centers for Disease Control and Prevention multidrug-resistant (MDR) Salmonella enterica serovar Heidelberg infections in people who reported contact with dairy calves. Federal state partners investigated this to identify source scope outbreak prevent further illnesses. Cases were defined as human infection caused by a strain that had one seven pulsed-field gel electrophoresis (PFGE) patterns or was related whole...
In the US, yersinosis was understood to predominantly occur in winter and among Black or African American infants Asian children. Increased use of culture-independent diagnostic tests (CIDTs) has led marked increases diagnoses. We describe differences epidemiology yersiniosis diagnosed by CIDT versus culture 10 US sites, identify determinants health associated with method. Annual reported incidence increased from 0.3/100 000 2010 1.3/100 2021, particularly adults ≥18 years, regardless race...
In the United States, typhoid vaccination is recommended for international travelers to areas with a recognized risk of exposure. Using MarketScan® Commercial Database from 2016 through 2022, we estimated costs by route (injectable vs. oral) and provider setting (clinic pharmacy). Of 165,930 vaccinated individuals, 99,471 received injectable 66,459 oral vaccines, 88% 17% respectively administered at clinics. Average were $132.91 per person [95% confidence interval (CI): $132.68-$133.13],...
Abstract Background Campylobacter is the leading cause of enteric bacterial infections in United States, causing an estimated 1.5 million illnesses annually. Antimicrobial therapy can reduce duration illness and limit complications; macrolides fluoroquinolones are typically recommended as first- second-line treatment, respectively. The Centers for Disease Control Prevention (CDC) investigates emerging resistance strains to identify potential sources collaborate on approaches its spread....
Salmonella serovar Kentucky is frequently isolated from chickens and dairy cattle, but recovery humans comparatively low based on the U.S. National Antimicrobial Resistance Monitoring System (NARMS) reports. We aimed to better describe genetic diversity, antimicrobial resistance, virulence determinants of isolates humans, food animal ceca, retail meat poultry products, imported foods other samples. analyzed genomes 774 found that 63% (54/86) human were sequence type (ST)198, 33% (29/86)...
is the most common cause of bacterial diarrhea in United States; resistance to macrolides and fluoroquinolones limits treatment options. We examined epidemiology US
Multidrug-resistant Shigella isolates with resistance to macrolides are an emerging public health threat. We define a plasmid/pathogen complex behind infections seen in the United States and globally vulnerable patient populations identify multiple outbreaks evidence of intercontinental transmission.
Cases of extensively drug-resistant (XDR) typhoid fever have been reported in the United States among patients who did not travel internationally. Clinicians should consider if and where patient traveled when selecting empiric treatment for fever. XDR be treated with a carbapenem, azithromycin, or both.
An increase in Mycoplasma pneumoniae-associated Stevens-Johnson syndrome (SJS) cases at a Colorado pediatric hospital led to an outbreak investigation. We describe the epidemiologic and molecular characteristics of M. pneumoniae among SJS case-patients surrounding community members during outbreak.M. polymerase chain reaction-positive respiratory specimens from 5 hospitals 4 referral laboratories underwent confirmatory reaction testing; positive then multilocus variable-number tandem-repeat...
The mcr-1 gene confers resistance to the polymyxins, including antibiotic colistin, a medication of last resort for multidrug-resistant infections. was first reported in 2015 food, animal, and patient isolates from China (1) is notable being plasmid-mediated colistin mechanism be identified. Plasmids can transferred between bacteria, potentially spreading other bacterial species. Since its discovery, has been Africa, Asia, Europe, South America, North America (2,3), United States, where it...
OBJECTIVES To define the scope of an outbreak Legionnaires’ disease (LD), to identify source, and stop transmission. DESIGN AND SETTING Epidemiologic investigation LD among patients a visitor exposed newly constructed hematology-oncology unit. METHODS An case was defined as radiographically confirmed pneumonia in person with positive urinary antigen testing and/or respiratory culture for Legionella exposure unit after February 20, 2014. Cases were classified definitely or probably...
Extensively drug-resistant Campylobacter jejuni infections cannot be treated with any commonly recommended antibiotics and pose an increasing public health threat.To investigate cases of extensively C associated pet store puppies describe the epidemiologic laboratory characteristics these infections.In August 2017, officials identified, via survey, patients who reported contact sold by stores. In conjunction state federal partners, Centers for Disease Control Prevention investigated...
Appropriate antibiotic use, in particular avoidance of antibiotics for upper respiratory infections likely to be caused by viruses, is a key component efforts slow the increase antibiotic-resistant infections. Studies suggest that Hispanic consumers might differ from non-Hispanic their knowledge and attitudes regarding use (4). To better understand health care provider consumer influence CDC analyzed national internet survey data collected participants living United States during 2012-2013....