A5036439096- Antibiotic Use and Resistance
- Clostridium difficile and Clostridium perfringens research
- Pneumonia and Respiratory Infections
- Nosocomial Infections in ICU
- Orthopedic Infections and Treatments
- Microscopic Colitis
- Metabolism and Genetic Disorders
- Total Knee Arthroplasty Outcomes
- Central Venous Catheters and Hemodialysis
- Fatty Acid Research and Health
- Dialysis and Renal Disease Management
- Cardiac, Anesthesia and Surgical Outcomes
- Tuberculosis Research and Epidemiology
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Surgical site infection prevention
- Maternal and Perinatal Health Interventions
- Orthopaedic implants and arthroplasty
- Streptococcal Infections and Treatments
- Emergency and Acute Care Studies
- Amino Acid Enzymes and Metabolism
- Diet and metabolism studies
- Primary Care and Health Outcomes
- Urinary Tract Infections Management
- Healthcare Policy and Management
Centers for Disease Control and Prevention
2014-2024
National Center for Emerging and Zoonotic Infectious Diseases
2013-2024
National University of Singapore
2022
National Center for Infectious Diseases
2021
Engineering Associates (United States)
2016
Emory and Henry College
2015
The Centers
2014
University of Florida
2012-2013
Emory University
2007-2011
Unnecessary antibiotic use (AU) contributes to increased rates of Clostridioides difficile infection (CDI). The impact restriction on hospital-onset CDI (HO-CDI) has not been assessed in a large group US acute care hospitals (ACHs).We examined cross-sectional and temporal associations between hospital-level AU HO-CDI using data from 549 ACHs. was defined as discharge with secondary International Classification Diseases, Ninth Revision, Clinical Modification code for (008.45), treatment...
Previous studies suggest that duration of antibiotic therapy for community-acquired pneumonia (CAP) often exceeds national recommendations and might represent an important opportunity to improve stewardship nationally. Our objective was determine the average length (LOT) patients treated uncomplicated CAP in US hospitals proportion with excessive durations. Records retrospective cohorts aged 18–64 years private insurance ≥65 Medicare hospitalized 2012–2013 were used. Inpatient LOT estimated...
Abstract In healthcare settings, Acinetobacter spp. bacteria commonly demonstrate antimicrobial resistance, making them a major treatment challenge. Nearly half of organisms from clinical cultures in the United States are nonsusceptible to carbapenem drugs. During 2012–2015, we conducted laboratory- and population-based surveillance selected metropolitan areas Colorado, Georgia, Maryland, Minnesota, New Mexico, York, Oregon, Tennessee determine incidence carbapenem-nonsusceptible A....
Background. Coronary artery bypass graft (CABG) and primary arthroplasty surgical site infection (SSI) rates are declining slower than other healthcare-associated rates. We examined antimicrobial prophylaxis (AMP) regimens used for these operations compared their spectrum of activity against reported SSI pathogens. Methods. Pathogen distributions CABG hip/knee complex SSIs (deep organ/space) to the National Healthcare Safety Network (NHSN) from 2006 through 2009 AMP (same procedures time...
There is growing interest in the usefulness of workplace as a site for promotion healthful food choices. The authors therefore analyzed data U.S. adults ( N = 1,918) who reported working outside home and eating lunch. majority (84.0%) workers had break room. About one half (54.0%) purchased lunch ≥ 2 times/week, with higher percentages males, Blacks, younger (age 18-34 years) versus older 55 years or older), obese normal-weight persons. most important choice value was convenience (34.3%),...
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the vulnerability of residents and staff members in long-term care facilities (LTCFs) (1).Although skilled nursing (SNFs) certified by Centers for Medicare & Medicaid Services (CMS) have federal COVID-19 reporting requirements, national surveillance data are less readily available other types LTCFs, such as assisted living (ALFs) those providing similar residential care.However, many state territorial health departments...
Genetic and microarray analyses have provided useful information in the area of plant pathogen interactions. Pseudomonas syringae pv. tomato DC3000 (Pst) causes bacterial speck disease tomato. Previous studies shown that changes response to infection at transcript level are variable different time points. This study provides not only on proteomic between a resistant susceptible genotype, but also an early late point. Using iTRAQ quantitative proteomics approach, we identified 2369 proteins...
Stomata on leaf epidermis formed by pairs of guard cells control CO(2) intake and water transpiration, respond to different environmental conditions. Stress-induced stomatal closure is mediated via an intricate hormone network in cells. Although methyl jasmonate (MeJA) has been intensively studied for its function plant defense, the molecular mechanisms underlying movement are not fully understood. Here we report effects MeJA Brassica napus H(2)O(2) production. Using isobaric tags relative...
Among dialysis facilities participating in a bloodstream infection (BSI) prevention collaborative, access-related BSI incidence rate improvements observed immediately following implementation of bundle interventions were sustained for up to 4 years. Overall, remained unchanged from baseline the current analysis. Infect Control Hosp Epidemiol 2016;37:863–866
Abstract Background As the US population ages, number of hip and knee arthroplasties is expected to increase. Because surgical site infections (SSIs) following these procedures contribute substantial morbidity, mortality, costs, we projected SSIs occur from 2020 through 2030. Methods We used a stochastic Poisson process project primary revision SSIs. Primary arthroplasty rates were calculated using annual estimates stratified by age gender 2012–2014 Nationwide Inpatient Sample standardized...
Most catheter-associated urinary tract infections (CAUTIs) are considered preventable and thus a potential target for health care quality improvement cost savings.We sought to estimate excess Medicare reimbursement, length of stay, inpatient death associated with CAUTI among hospitalized beneficiaries.Using retrospective cohort design linked claims National Healthcare Safety Network data from 2009, we compared reimbursement between beneficiaries without CAUTIs.Fee-for-service aged 65 years...
Abstract Previously reported associations between hospital-level antibiotic use and hospital-onset Clostridioides difficile infection (HO-CDI) were reexamined using 2012–2018 data from a new cohort of US acute-care hospitals. This analysis revealed significant positive total, third-generation, fourth-generation cephalosporin, fluoroquinolone, carbapenem, piperacillin-tazobactam HO-CDI rates, confirming previous findings.
ObjectivesIn December 2020, CDC launched the Pharmacy Partnership for Long-Term Care Program to facilitate COVID-19 vaccination of residents and staff in long-term care facilities (LTCFs), including assisted living (AL) other residential (RC) communities. We aimed assess vaccine uptake these communities identify characteristics that might impact uptake.DesignCross-sectional study.Setting ParticipantsAL/RC had ≥1 on-site clinic during 18, 2020–April 21, 2021.MethodsWe estimated using...
The reliability of studies investigating biological and therapeutic factors that influence body composition in PKU patients depends on accurate anthropometric measurements.To determine the precision six skinfold equations versus air displacement plethysmography (ADP) for predicting fat (BF) percentage female adolescents with PKU.Skinfold ADP measurements were recorded from a cross section 59 PKU, ages 10-19 years. Anthropometric measures used to calculate percent BF using published by...
Most new patients with end-stage renal disease (ESRD) initiate hemodialysis (HD) a central venous catheter (CVC) and later transition to permanent vascular access lower infection risk. The benefit of early fistula use in preventing severe infections is incompletely understood. We examined patients' first subsequent transitions between accesses during the year HD estimate risk for bloodstream (BSI) associated incident time-dependent access.A retrospective cohort study using enhanced 5%...
Abstract Objective: To compare risk of surgical site infection (SSI) following cesarean delivery between women covered by Medicaid and private health insurance. Study design: Retrospective cohort. population: Cesarean deliveries or insurance reported to the National Healthcare Safety Network (NHSN) state inpatient discharge databases hospitals in California (2011–2013). Methods: Deliveries NHSN were linked identify SSIs 30 days delivery, primary payer, patient procedure characteristics....
Abstract Objectives: The coronavirus disease 2019 pandemic caused substantial changes to healthcare delivery and antibiotic prescribing beginning in March 2020. To assess impact on Clostridioides difficile infection (CDI) rates, we described patients trends facility-level incidence, testing percent positivity during 2019–2020 a large cohort of US hospitals. Methods: We estimated compared rates community-onset CDI (CO-CDI) per 10,000 discharges, hospital-onset (HO-CDI) patient days, C....