- Chromium effects and bioremediation
- Microplastics and Plastic Pollution
- Mercury impact and mitigation studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 Clinical Research Studies
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- COVID-19 epidemiological studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Viral gastroenteritis research and epidemiology
- Biosensors and Analytical Detection
- COVID-19 and healthcare impacts
- Advanced Proteomics Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
Centers for Disease Control and Prevention
2021-2023
New York City Department of Health and Mental Hygiene
2018-2021
University of Georgia
2011-2018
Importance As self-collected home antigen tests become widely available, a better understanding of their performance during the course SARS-CoV-2 infection is needed. Objective To evaluate diagnostic compared with reverse transcription–polymerase chain reaction (RT-PCR) and viral culture by days from illness onset, as well user acceptability. Design, Setting, Participants This prospective cohort study was conducted January to May 2021 in San Diego County, California, metropolitan Denver,...
To address high COVID-19 burden in U.S. nursing homes, rapid SARS-CoV-2 antigen tests have been widely distributed those facilities. However, performance data are lacking, especially asymptomatic people.
Abstract Background Serosurveys help to ascertain burden of infection. Prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serosurveys in New York City (NYC) used nonrandom samples. During June–October 2020, the NYC Health Department conducted a population-based survey estimating SARS-CoV-2 antibody prevalence adults. Methods Participants were recruited from 2020 Community Survey. We estimated citywide and stratified using hybrid design: serum tested with DiaSorin LIAISON...
The protean chemical properties of mercury have long made it attractive for diverse applications, but its toxicity requires great care in use, disposal, and recycling. Mercury occurs multiple forms, the molecular basis distinct various forms is only partly understood. Global transcriptomics applied over time can reveal how a cell recognizes toxicant what cellular subsystems marshals to repair recover from damage. longitudinal effects on transcriptome exponential phase E. coli were compared...
The identification of peptides that result from post-translational modifications is critical for understanding normal pathways cellular regulation as well identifying damage from, or exposures to xenobiotics, i.e. the exposome. However, because their low abundance in proteomes, effective detection modified by mass spectrometry (MS) typically requires enrichment eliminate false identifications. We present a new method confidently with mercury (Hg)-containing adducts based on influence...
Abstract Repeated antigen testing of 12 severe acute respiratory coronavirus virus 2 (SARS-CoV-2)–positive nursing home residents using Abbott BinaxNOW identified 9 (100%) culture-positive specimens up to 6 days after initial positive test. Antigen positivity lasted 2–24 days. might last beyond the infectious period, but it was reliable in with evidence early infection.
In 2017, the Centers for Disease Control and Prevention (CDC) established Antimicrobial Resistance Laboratory Network to improve domestic detection of multidrug-resistant organisms. CDC four laboratories evaluated a commercial broth microdilution panel. susceptibility testing using Sensititre GN7F (ThermoFisher Scientific, Lenexa, KS) was by 100 Food Drug Administration AR Isolate Bank isolates [40 Enterobacterales (ENT), 30
There are limited data describing SARS-CoV-2-specific immune responses and their durability following infection vaccination in nursing home residents. We conducted a prospective longitudinal evaluation of 11 consenting SARS-CoV-2-positive residents to evaluate the quantitative titers binding antibodies detected after SARS-CoV-2 subsequent COVID-19 vaccination. The included nine visits over 150 days from October 25, 2020, through April 1, 2021. Visits questionnaire administration, blood...
ABSTRACT Background The protean chemical properties of mercury have long made it attractive for diverse applications, but its toxicity requires great care in use, disposal, and recycling. Mercury occurs multiple forms, the molecular basis distinct various forms is only partly understood. Global transcriptomics applied over time can reveal how a cell recognizes toxicant what cellular subsystems marshals to repair recover from damage. longitudinal effects on transcriptome exponential phase E....