Rebecca J. Chancey
- Parasites and Host Interactions
- Trypanosoma species research and implications
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Research on Leishmaniasis Studies
- Parasite Biology and Host Interactions
- Respiratory viral infections research
- COVID-19 and Mental Health
- Parasitic Infections and Diagnostics
- Dermatological diseases and infestations
- Viral gastroenteritis research and epidemiology
- Synthesis and Biological Evaluation
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Innovations in Medical Education
- Streptococcal Infections and Treatments
- Human Resource Development and Performance Evaluation
- Travel-related health issues
- Coenzyme Q10 studies and effects
- Biosensors and Analytical Detection
- Clostridium difficile and Clostridium perfringens research
- Transplantation: Methods and Outcomes
- Helminth infection and control
- Insects and Parasite Interactions
Centers for Disease Control and Prevention
2020-2024
Division of Parasitic Diseases and Malaria
2018-2023
Center for Global Health
2018-2023
RELX Group (United States)
2022
Epidemic Intelligence Service
2018-2020
National Center for Emerging and Zoonotic Infectious Diseases
2020
Baylor College of Medicine
2018
Duke Medical Center
2009-2017
Duke University Hospital
2009
Abstract Background The evidence base for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is nascent. We sought to characterize SARS-CoV-2 transmission within US households and estimate the household secondary infection rate (SIR) inform strategies reduce transmission. Methods recruited patients with laboratory-confirmed their contacts in Utah Wisconsin during 22 March 2020–25 April 2020. interviewed all obtain demographics medical histories. At initial visit, 14 days later,...
Importance As self-collected home antigen tests become widely available, a better understanding of their performance during the course SARS-CoV-2 infection is needed. Objective To evaluate diagnostic compared with reverse transcription–polymerase chain reaction (RT-PCR) and viral culture by days from illness onset, as well user acceptability. Design, Setting, Participants This prospective cohort study was conducted January to May 2021 in San Diego County, California, metropolitan Denver,...
To better understand severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding and infectivity, we estimated SARS-CoV-2 RNA duration, described participant characteristics associated with the first negative rRT-PCR test (resolution), determined if replication-competent viruses was recoverable ≥10 days after symptom onset.We collected serial nasopharyngeal specimens from 109 individuals rRT-PCR-confirmed COVID-19 in Utah Wisconsin. We calculated viral resolution probability using...
Limited data exist on severe acute respiratory syndrome coronavirus 2 in children. We described infection rates and symptom profiles among pediatric household contacts of individuals with disease 2019.We enrolled 2019 their contacts, assessed daily symptoms prospectively for 14 days, obtained specimens real-time reverse transcription polymerase chain reaction serology testing. Among (<18 years), we transmission, the risk factors infection, calculated positive negative predictive values....
In-person learning benefits children and communities (1).Understanding the context in which transmission of SARS-CoV-2, virus that causes coronavirus disease 2019 , occurs schools is critical to improving safety inperson learning.During December 1, 2020-January 22, 2021, Cobb Douglas Public Health (CDPH), Georgia Department (GDPH), CDC investigated SARS-CoV-2 eight public elementary a single school district.COVID-19 cases* among educators students were either self-reported or identified by...
Improved understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spectrum disease is essential for clinical and public health interventions. There are limited data on mild or asymptomatic infections, but recognition these individuals key as they contribute to viral transmission. We describe the symptom profiles from with SARS-CoV-2 infection.From 22 March April 2020 in Wisconsin Utah, we enrolled prospectively observed 198 household contacts exposed SARS-CoV-2....
Rapid Cycle Deliberate Practice (RCDP) is a team-based simulation method, emphasizing repetitive practice over reflective debriefing, with progressively more challenging rounds, frequent starts and stops, direct coaching. Although some studies have shown improved performance, no study has evaluated learners' perceptions. We aimed to explore experiences during RCDP.This was qualitative of participants' perceptions regarding RCDP their pediatric emergency medicine rotation. Participants...
In Spring 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.7 (Alpha) became the predominant variant in United States. Research suggests that Alpha has increased transmissibility compared with non-Alpha lineages. We estimated household secondary infection risk (SIR), assessed characteristics associated transmission, and symptoms of persons infections.We followed households SARS-CoV-2 for weeks San Diego County metropolitan Denver, January to April 2021. collected...
To inform prevention strategies, we assessed the extent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and settings in which occurred a Georgia public school district.During 1 December 2020-22 January 2021, SARS-CoV-2-infected index cases their close contacts schools were identified by health officials. For in-school contacts, symptoms offered SARS-CoV-2 reverse-transcription polymerase chain reaction (RT-PCR) testing; performed epidemiologic investigations...
Abstract Eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis has been reported in several southern U.S. states and Hawai‘i. We present the first locally acquired human cases of A. three children Florida, occurring between June 2021 January 2022. Clinicians should be attuned to this possible diagnosis region.
Abstract Background The Centers for Disease Control and Prevention led an investigation to determine if Strongyloides infection in a right kidney recipient was existing chronic infection, or the transmitted from infected organ donor. Methods Evidence regarding donor recipients testing, treatment, risk factors were gathered evaluated. case classification algorithm created by Transmission Advisory Committee utilized. Results had infection; banked specimen, submitted serology testing 112 days...
To assess the household secondary infection risk (SIR) of B.1.1.7 (Alpha) and non-Alpha lineages severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among children.During January to April 2021, we prospectively followed households with a SARS-CoV-2 infection. We collected questionnaires, serial nasopharyngeal swabs for reverse transcription polymerase chain reaction testing whole genome sequencing, blood samples serology testing. calculated SIRs by primary case age (pediatric vs...
Chagas disease, or American trypanosomiasis, is caused by the parasite Trypanosoma cruzi. disease endemic in rural areas of Latin America, but T. cruzi, triatomine vectors, infected mammalian reservoir hosts, and rare cases autochthonous vector borne transmission have been reported United States (1). Possible modes include following: via skin mucosal contact with feces bugs, congenital, blood transfusion, organ transplantation, laboratory accident. can be treated benznidazole (commercially...
Abstract Background Optimized symptom-based COVID-19 case definitions that guide public health surveillance and individual patient management in the community may assist pandemic control. Methods We assessed diagnostic performance of existing cases (e.g. influenza-like illness, COVID-like illness) using symptoms reported from 185 household contacts to a PCR-confirmed Wisconsin Utah, United States. stratified analyses between adults children. also constructed novel for comparison. Results...
Abstract Limited data exist on human Macracanthorhynchus infections. We report an asymptomatic 17-month-old who passed eggs and adult ingens worm, indicating parasite maturation reproduction. may have a greater capacity to mature in humans versus hirudinaceus.
We describe a case of Baylisascaris procyonis roundworm infection in child Washington, USA, with autism spectrum disorder. Environmental assessment confirmed nearby raccoon habitation and B. eggs. infections should be considered potential cause human eosinophilic meningitis, particularly among young children persons developmental delays.
Respiratory viral infections (RVI) are a frequent cause of morbidity and mortality in hematopoietic stem cell transplant (HSCT) patients. We examined clinical characteristics respiratory detection asymptomatic pediatric HSCT pre-transplant patients symptomatic post-transplant Coxsackie/echovirus (most common virus detected pre post-transplant), rhinovirus, coronavirus were at the first event suggesting persistent detection. None associated with there was no increase noted
To assess appropriate drug treatment of parasitic diseases in the United States, we examined rates 11 selected infections with standard-of-care prescription drugs and compared them to two more common bacterial (Clostridioides difficile streptococcal pharyngitis). We used 2013 2019 IBM® MarketScan® Commercial Claims Encounters Multi-State Medicaid databases, which included up 7 years data for approximately 88 million 17 individuals, respectively, estimate each infection. The number patients...
Abstract Human African trypanosomiasis incidence has declined, but diagnosis remains difficult, especially in nonendemic areas. Our patient presented with fever, progressive lethargy, and weight loss for 5 months had previously traveled to Ghana Cameroon not been areas recently reported trypanosomiasis. Extensive workup was negative, except lymphocytic pleocytosis cerebrospinal fluid; ultimately, a bone marrow aspiration revealed necrotizing granulomatous inflammation 2 trypanosomes...