A5036896044- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Reproductive Health and Technologies
- Probiotics and Fermented Foods
- Pneumocystis jirovecii pneumonia detection and treatment
- Grief, Bereavement, and Mental Health
- Plant Pathogens and Fungal Diseases
- Infectious Diseases and Mycology
- Assisted Reproductive Technology and Twin Pregnancy
- SARS-CoV-2 detection and testing
- COVID-19 and Mental Health
- Nosocomial Infections in ICU
- Patient Satisfaction in Healthcare
- Pleural and Pulmonary Diseases
- Reproductive tract infections research
- Yeasts and Rust Fungi Studies
- Neutropenia and Cancer Infections
- Fungal Plant Pathogen Control
- Antimicrobial agents and applications
- Trauma and Emergency Care Studies
- HIV, Drug Use, Sexual Risk
- Gun Ownership and Violence Research
Centers for Disease Control and Prevention
2018-2024
National Center for Injury Prevention and Control
2024
Florida Department of Health
2024
Indiana State Department of Health
2024
New Jersey Department of Health
2024
AID Atlanta
2024
Philadelphia Department of Public Health
2022
Hospital of the University of Pennsylvania
2022
United States Department of Health and Human Services
2020
National Center for Emerging and Zoonotic Infectious Diseases
2019-2020
In less than a decade, C. auris has emerged in health care settings worldwide; this species is capable of colonizing skin and causing outbreaks invasive candidiasis. contrast to other Candida species, unique its ability spread via nosocomial transmission high rates drug resistance. As part the public response, whole-genome sequencing played major role characterizing dynamics detecting new introductions. Through global collaboration, we assessed genome evolution isolates from 19 countries....
In July 2020, the Florida Department of Health was alerted to three Candida auris bloodstream infections and one urinary tract infection in four patients with coronavirus disease 2019 (COVID-19) who received care same dedicated COVID-19 unit an acute hospital (hospital A). C. is a multidrug-resistant yeast that can cause invasive infection. Its ability colonize asymptomatically persist on surfaces has contributed previous outbreaks health settings (1-7). Since first case identified 2017,...
Although rare, Candida auris resistant to all three classes of commonly used antifungal drugs was identified in patients New York. CDC considers C. an urgent threat, the highest category concern.
Background: Candida auris is an emerging fungal threat that has been spreading in the United States since it was first reported 2016. Objective: To describe recent changes U.S. epidemiology of C occurring from 2019 to 2021. Design: Description national surveillance data. Setting: States. Patients: Persons with any specimen positive for auris. Measurements: Case counts Centers Disease Control and Prevention by health departments, volume colonization screening, antifungal susceptibility...
Candida auris is an emerging multidrug-resistant yeast first described in 2009 that has since caused healthcare-associated outbreaks of severe human infections around the world. In some hospitals, it become a leading cause invasive candidiasis. C. markedly different from most other pathogenic species its genetics, antifungal resistance, and ability to spread between patients. The reasons why this fungus began spreading widely last decade remain mystery. We examine available data on related...
The emerging yeast Candida auris can be highly drug resistant, causing invasive infections, and large outbreaks. C. went from an unknown pathogen a decade ago to being reported in over thirty countries on six continents.
Abstract Background Candida auris is an emerging, multidrug-resistant yeast that spreads in healthcare settings. People colonized with C. can transmit this pathogen and are at risk for invasive infections. New York State (NYS) has the largest US burden (>500 infected people); many individuals mechanically ventilated or have tracheostomy, residents of ventilator-capable skilled nursing facilities (vSNF). We evaluated factors associated colonization among vSNF to inform prevention...
In-person learning benefits children and communities (1).Understanding the context in which transmission of SARS-CoV-2, virus that causes coronavirus disease 2019 , occurs schools is critical to improving safety inperson learning.During December 1, 2020-January 22, 2021, Cobb Douglas Public Health (CDPH), Georgia Department (GDPH), CDC investigated SARS-CoV-2 eight public elementary a single school district.COVID-19 cases* among educators students were either self-reported or identified by...
Since the identification of first 2 Candida auris cases in Chicago, Illinois, 2016, ongoing spread has been documented Chicago area. We describe C. emergence high-acuity, long-term healthcare facilities and present a case study public health response to carbapenemase-producing organisms (CPOs) at one ventilator-capable skilled nursing facility (vSNF-A).We performed point prevalence surveys (PPSs) identify patients colonized with infection-control (IC) assessments provided support for IC...
Using a large US hospital database, we describe 192 Candida auris‒associated hospitalizations during 2017-2022, including 38 (20%) C. auris bloodstream infections. Hospitalizations involved extensive concurrent conditions and healthcare use; estimated crude mortality rate was 34%. These findings underscore the continued need for public health surveillance containment efforts.
Candida auris is an emerging multidrug-resistant yeast that contaminates healthcare environments causing healthcare-associated outbreaks. The mechanisms facilitating contamination are not established.
Problem/Condition: In 2021, approximately 75,000 persons died of violence-related injuries in the United States.This report summarizes data from CDC's National Violent Death Reporting System (NVDRS) on violent deaths that occurred 48 states, District Columbia, and Puerto Rico 2021.Results are reported by sex, age group, race ethnicity, method injury, type location where injury occurred, circumstances other selected characteristics.This introduces additional incident circumstance variables,...
The recent emergence of a multidrug-resistant yeast, Candida auris, has drawn attention to the closely related species from C. haemulonii complex that include haemulonii, duobushaemulonii, pseudohaemulonii and recently identified vulturna. Here, we used antifungal susceptibility testing whole genome sequencing (WGS) investigate drug resistance genetic diversity among isolates different geographic areas in order assess population structure extent clonality strains. Although most all four were...
Undetected infection with SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) contributes to transmission in nursing homes, settings where large outbreaks high resident mortality have occurred (1,2). Facility-wide testing of residents and health care personnel (HCP) can identify asymptomatic presymptomatic infections facilitate prevention control interventions (3-5). Seven state or local departments conducted initial facility-wide staff members 288 homes during March...
Candida auris is a difficult-to-diagnose multidrug-resistant yeast that can cause invasive infections with high mortality. Since emerging in 2009, this pathogen has been associated numerous outbreaks around the world. Whole genome sequencing (WGS) instrumental for understanding emergence and local transmission of pathogen.To describe clinical, molecular characteristics infection clinical outcome our centre.Patients positive cultures were identified microbiology database. Clinical antifungal...
Abstract We tested 9 disinfectants against Candida auris using the quantitative disk carrier method EPA-MB-35-00: 5 products with hydrogen peroxide or alcohol-based chemistries were effective and 4 quaternary ammonium compound-based not. This work supported a FIFRA Section 18 emergency exemption granted by US Environmental Protection Agency to expand disinfectant guidance for C. auris.
To inform prevention strategies, we assessed the extent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and settings in which occurred a Georgia public school district.During 1 December 2020-22 January 2021, SARS-CoV-2-infected index cases their close contacts schools were identified by health officials. For in-school contacts, symptoms offered SARS-CoV-2 reverse-transcription polymerase chain reaction (RT-PCR) testing; performed epidemiologic investigations...
Candida auris is a human pathogen of high concern due to its extensive antifungal drug resistance and mortality rates associated with invasive infections. skin colonization persistence on environmental surfaces make this difficult control once it enters health care facility. Residents in long-term hospitals nursing homes are especially vulnerable.