A5008885135- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Coral and Marine Ecosystems Studies
- Microbial Community Ecology and Physiology
- Plant Pathogens and Fungal Diseases
- Biosensors and Analytical Detection
- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- SARS-CoV-2 detection and testing
- Gut microbiota and health
- Bacterial Identification and Susceptibility Testing
- Marine and coastal ecosystems
- Antibiotic Use and Resistance
- Nail Diseases and Treatments
- Probiotics and Fermented Foods
- Marine and coastal plant biology
- Methane Hydrates and Related Phenomena
- Advanced biosensing and bioanalysis techniques
- Infectious Diseases and Mycology
- Atmospheric and Environmental Gas Dynamics
- Antimicrobial Resistance in Staphylococcus
- Antimicrobial agents and applications
- Celiac Disease Research and Management
- Patient Satisfaction in Healthcare
- Fungal and yeast genetics research
Centers for Disease Control and Prevention
2017-2024
Alberta Hospital Edmonton
2024
National Center for Emerging and Zoonotic Infectious Diseases
2017-2022
United States Department of Health and Human Services
2019-2021
Oregon State University
2012-2020
University of Madras
2018
Monterey Bay Aquarium Research Institute
2008-2012
Florida International University
2012
University of Tennessee at Knoxville
2006
Universidad de La Laguna
2006
Syndiniales are a parasitic order within the eukaryotic lineage Dinophyceae (Alveolata). Here, we analysed taxonomy of this group using 43655 18S rRNA gene sequences obtained either from environmental data sets or cultures, including 6874 study derived Atlantic and Mediterranean waters. A total 5571 out fell Dinophyceae. Both bayesian maximum likelihood phylogenies placed in five main groups (I-V), as monophyletic at base 'core' dinoflagellates (all except Syndiniales), although latter...
Abstract Losses of corals worldwide emphasize the need to understand what drives reef decline. Stressors such as overfishing and nutrient pollution may reduce resilience coral reefs by increasing coral–algal competition reducing recruitment, growth survivorship. Such effects themselves develop via several mechanisms, including disruption microbiomes. Here we report results a 3-year field experiment simulating pollution. These stressors increase turf macroalgal cover, destabilizing...
ABSTRACT The emerging multidrug-resistant pathogenic yeast Candida auris represents a serious threat to global health. Unlike most other species, this organism appears be commonly transmitted within health care facilities and causes care-associated outbreaks. To better understand the epidemiology of pathogen, we investigated ability C. persist on plastic surfaces common in settings compared with that parapsilosis , species known colonize skin plastics. Specifically, compiled comparative...
In less than a decade, C. auris has emerged in health care settings worldwide; this species is capable of colonizing skin and causing outbreaks invasive candidiasis. contrast to other Candida species, unique its ability spread via nosocomial transmission high rates drug resistance. As part the public response, whole-genome sequencing played major role characterizing dynamics detecting new introductions. Through global collaboration, we assessed genome evolution isolates from 19 countries....
Flux of dimethylsulfide (DMS) from ocean surface waters is the predominant natural source sulfur to atmosphere and influences climate by aerosol formation. Marine bacterioplankton regulate flux converting precursor dimethylsulfoniopropionate (DMSP) either DMS or compounds that are not climatically active. Through discovery a glycine cleavage T-family protein with DMSP methyltransferase activity, marine in Roseobacter SAR11 taxa were identified as primary mediators demethylation...
Candida auris, an emerging fungus that can cause invasive infections, is associated with high mortality and often resistant to multiple antifungal drugs. C. auris was first described in 2009 after being isolated from external ear canal discharge of a patient Japan (1). Since then, reports including bloodstream have been published several countries, Colombia, India, Israel, Kenya, Kuwait, Pakistan, South Africa, Korea, Venezuela, the United Kingdom (2-7). To determine whether present States...
Abstract Background Candida auris is a multidrug-resistant yeast associated with hospital outbreaks worldwide. During 2015–2016, multiple were reported in Colombia. We aimed to understand the extent of contamination healthcare settings and characterize molecular epidemiology C. Methods sampled patients, patient contacts, workers, environment 4 hospitals recent outbreaks. Using standardized protocols, people swabbed at different body sites. Patient procedure rooms sectioned into zones...
Wastewater surveillance is a valuable tool that can be used to track infectious diseases in community. In September 2020, the Centers for Disease Control and Prevention (CDC) established National Surveillance System (NWSS) coordinate build nation's capacity detect quantify concentrations of SARS-CoV-2 RNA U.S. wastewater. This first summary NWSS, covering 1, 2020 December 31, 2022. Through partnerships with state, tribal, local, territorial health departments, NWSS became national platform...
Candida auris is an emerging multidrug-resistant yeast first described in 2009 that has since caused healthcare-associated outbreaks of severe human infections around the world. In some hospitals, it become a leading cause invasive candidiasis. C. markedly different from most other pathogenic species its genetics, antifungal resistance, and ability to spread between patients. The reasons why this fungus began spreading widely last decade remain mystery. We examine available data on related...
With the continued and unprecedented decline of coral reefs worldwide, evaluating factors that contribute to demise is critical importance. As cover declines, macroalgae are becoming more common on tropical reefs. Interactions between these corals may alter microbiome, which thought play an important role in colony health survival. Together, such changes benthic microbiome result a feedback mechanism contributes additional loss. To determine if we conducted field-based experiment Porites...
Candida auris is an emerging fungal pathogen of rising concern due to global spread, the ability cause healthcare-associated outbreaks, and antifungal resistance. Genomic analyses revealed that early contemporaneously detected cases C. were geographically stratified into four major clades. While Clades I, III, IV are responsible for ongoing outbreaks invasive multidrug-resistant infections, Clade II, also termed East Asian clade, consists primarily ear infection, often susceptible all drugs,...
The emerging yeast Candida auris can be highly drug resistant, causing invasive infections, and large outbreaks. C. went from an unknown pathogen a decade ago to being reported in over thirty countries on six continents.
Early detection of emerging SARS-CoV-2 variants is critical to guiding rapid risk assessments, providing clear and timely communication messages, coordinating public health action. CDC identifies monitors novel through diverse surveillance approaches, including genomic, wastewater, traveler-based, digital (e.g., global data repositories, news, social media). The variant BA.2.86 was first sequenced in Israel reported on August 13, 2023. U.S. COVID-19 case caused by this 17, 2023, after a...
Phosphate (PO(4)) is an important limiting nutrient in marine environments. Marine cyanobacteria scavenge PO(4) using the high-affinity periplasmic phosphate binding protein PstS. The pstS gene has recently been identified genomes of cyanobacterial viruses as well. Here, we analyse genes encoding transporters from that infect eukaryotic phytoplankton. We inorganic transporter-encoding PHO4 superfamily several virus genomes, along with other genes. Homologues viral pho4 were also genome...
Coral microbiomes are known to play important roles in organismal health, response environmental stress, and resistance disease. The coral microbiome contains diverse assemblages of resident bacteria, ranging from defensive metabolic symbionts opportunistic bacteria that may turn harmful compromised hosts. However, little is about how these bacterial interactions influence the mechanism controls overall structure, stability, function microbiome. We sought test dynamics were affected by...
The recent emergence of the multidrug-resistant and pathogenic yeast Candida auris continues to cause public health concern worldwide. C. is alarming because it causes care-associated outbreaks can establish invasive infections with high mortality rates. Transmission between patients facilitated by ability persistently colonize multiple body sites, including skin, survive for weeks on surfaces in care settings. Rapid identification colonized needed implement timely infection control...