A5088993666- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Respiratory viral infections research
- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Streptococcal Infections and Treatments
- Vibrio bacteria research studies
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Nosocomial Infections in ICU
- Bacteriophages and microbial interactions
- Antibiotic Use and Resistance
- Listeria monocytogenes in Food Safety
- Pneumocystis jirovecii pneumonia detection and treatment
- Enzyme Production and Characterization
- Plant Pathogens and Fungal Diseases
- Food Safety and Hygiene
- Infective Endocarditis Diagnosis and Management
- Leptospirosis research and findings
- Postharvest Quality and Shelf Life Management
- Plant Physiology and Cultivation Studies
- Zoonotic diseases and public health
- Infections and bacterial resistance
Instituto Nacional de Salud
2016-2025
Instituto Nacional de Salud
2014-2023
Colombian Corporation for Agricultural Research - AGROSAVIA
2020
Centers for Disease Control and Prevention
2016
National University of Mar del Plata
2009-2011
Experimental Station
2009
Abstract Background Candida auris is a multidrug-resistant yeast associated with hospital outbreaks worldwide. During 2015–2016, multiple were reported in Colombia. We aimed to understand the extent of contamination healthcare settings and characterize molecular epidemiology C. Methods sampled patients, patient contacts, workers, environment 4 hospitals recent outbreaks. Using standardized protocols, people swabbed at different body sites. Patient procedure rooms sectioned into zones...
BackgroundThe Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, and agalactiae. We aimed analyse incidence distribution these during first 2 years compared preceding pandemic.MethodsFor this prospective analysis, laboratories in 30 countries territories representing five continents submitted surveillance data from Jan...
In Colombia, approximately 105,000 suspected cases of Zika virus disease (diagnosed based on clinical symptoms, regardless laboratory confirmation) were reported during August 9, 2015-November 12, 2016, including nearly 20,000 in pregnant women (1,2). infection pregnancy is a known cause microcephaly and serious congenital brain abnormalities has been associated with other birth defects related to central nervous system damage (3). Colombia's Instituto Nacional de Salud (INS) maintains...
Abstract We have developed an efficient and inexpensive pipeline for streamlining large-scale collection genome sequencing of bacterial isolates. Evaluation this method involved a worldwide research collaboration focused on the model organism Salmonella enterica , 10KSG consortium. Following optimization logistics that shipping isolates as thermolysates in ambient conditions, project assembled diverse 10,419 from low- middle-income countries. The genomes were sequenced using LITE library...
Since 2016, in Colombia, ongoing transmission of
Bacteria that produce the broad-spectrum Carbapenem antibiotic New Delhi Metallo-β-lactamase (NDM) place a burden on health care systems worldwide, due to limited treatment options for infections caused by them and rapid global spread of this resistance mechanism. Although it is believed associated gene blaNDM-1 originated in Acinetobacter spp., role Enterobacteriaceae its dissemination remains unclear. In study, we used whole genome sequencing investigate dynamics blaNDM-1-positive plasmids...
ABSTRACT Polymyxins are last-resort antimicrobial agents used to treat infections caused by carbapenem-resistant Enterobacteriaceae . Due the worldwide dissemination of polymyxin resistance in animal and human isolates, we aimed characterize associated with presence mcr-1 nonfermenter Gram-negative bacilli, using isolates collected retrospectively Colombia from 2002 2016. A total 5,887 clinical were studied, 513 found be resistant polymyxins. Susceptibility colistin was confirmed broth...
The World Health Organization (WHO) coordinates the Global Invasive Bacterial Vaccine-Preventable Diseases (IB-VPD) Surveillance Network to support vaccine introduction decisions and use. network was established strengthen surveillance laboratory confirmation of meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis.
Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an emerging public health problem. This study explores the specifics of CRKP epidemiology in Colombia based on whole genome sequencing (WGS) National Reference Laboratory at Instituto Nacional de Salud (INS)’s 2013–2017 sample collection. Methods A total 425 isolates from 21 departments were analyzed by HiSeq-X10®Illumina high-throughput sequencing. Bioinformatic analysis was performed, primarily using pipelines...
Leptospirosis is a common zoonoses and major global public health threat. Most cases are mild, typically presenting as non-specific acute febrile illness. However, leptospirosis can have life-threatening manifestations, including pulmonary hemorrhage syndrome, kidney injury. In Colombia, notification lab-confirmation of suspected human mandatory. little known about the demographic clinical factors associated with severe leptospirosis, which could help to reduce complications mortality. Our...
Brazil faces solid waste management challenges despite its strong agricultural sector. The bioeconomy provides a solution by converting by-products into valuable resources. Wheat, key crop, produces abundant suitable for enzyme production through solid-state fermentation (SSF). This review examines the use of wheat by-products, particularly bran, in via SSF to support sustainable industrial practices and enhance bioeconomy. From 811 articles reviewed, 16 were analyzed detail, with focus on...
Salmonella enterica serovar Typhimurium is a prevalent food-borne pathogen that usually associated with gastroenteritis infection. S. also major cause of bloodstream infections in sub-Saharan Africa, and responsible for invasive non-typhoidal (iNTS) disease. The causes infection Colombia, but there has been lack information about the isolates were responsible. Here, we investigated genomic characteristics 270 from patients collected between 1997 2017. We used whole-genome sequencing to...
We used whole-genome sequence typing (WGST) to investigate an outbreak of Sarocladium kiliense bloodstream infections (BSI) associated with receipt contaminated antinausea medication among oncology patients in Colombia and Chile during 2013-2014. Twenty-five isolates (18 from 7 vials) 11 control unrelated this were subjected WGST elucidate a source infection. All nearly indistinguishable (<5 single-nucleotide polymorphisms), >21,000 polymorphisms identified isolates, suggesting point for...
After a 2016 CDC alert describing infections caused by the multidrug-resistant fungus Candida auris (1), Colombian Instituto Nacional de Salud (INS) queried country's WHONET † database of invasive isolates to detect previous C. infections.No were identified during 2012-2016.However, is often misidentified as haemulonii (2), yeast that rarely causes infections, and 75 reported May 2013-August 2016.These came primarily from patients in intensive care units north region, approximately 350-600...
Quality changes of blueberries (Vacccinium corymbosum L. cv Brigitta) were evaluated during CA storage (0 degrees C) with different concentrations CO(2) (5%, 10%, and 15%) combined 5% O(2), respectively. Atmospheric air (20.9% O(2)+ 0.03% CO(2)) was used as control. From samples taken at 0, 24, 48 d storage, unmarketable fruits weight loss recorded well color (h), firmness (g), soluble solid content (%), titratable acidity (% citric acid), ratio, the monomeric anthocyanin (ppm). At each...
Since the first report of Candida auris in 2016, Colombian Instituto Nacional de Salud (INS) has implemented a national surveillance emerging multidrug-resistant fungus.This summarises findings this laboratory-based from March 2016 to December 2020.A total 1720 C. cases were identified, including 393 (23%) colonisation and 1327 (77%) clinical cases. Cases reported 20 32 (62%) departments Colombia involved hospitals 33 cities. The median age patients was 34 years; 317 (18%) children under 16...
Background Acute undifferentiated febrile illness is a common challenge for clinicians, especially in tropical and subtropical countries. Incorrect or delayed diagnosis of patients may result medical complications preventable deaths. Common causes acute Colombia include leptospirosis, rickettsioses, dengue fever, malaria, chikungunya, Zika virus infection. In this study, we described the postmortem reported as suspected cases leptospirosis through national surveillance Colombia, 2016–2019....
Background Meningococcal carriage studies are important to improve our understanding of the epidemiology meningococcal disease. The aim this study was determine prevalence and phenotypic genotypic characteristics isolates collected from a sample students in city Bogotá, Colombia. Materials Methods A total 1459 oropharyngeal samples were aged 15–21 years attending secondary schools universities. Swabs plated on Thayer Martin agar N. meningitidis identified by standard microbiology methods...
Introducción. En el tercer trimestre de 2012, comenzó a operar Sistema Nacional Vigilancia Resistencia Antimicrobiana en las infecciones asociadas la atención salud, con fin recabar y analizar información referente al problema Colombia.Objetivo. Describir los perfiles resistencia resultados vigilancia por laboratorio base datos recolectados Sistema.Materiales métodos. Se hizo un estudio descriptivo retrospectivo del Salud Pública, Sivigila, 1 septiembre 2012 31 diciembre 2014, así como bases...
Providencia rettgeri is a nosocomial pathogen associated with urinary tract infections and related to Healthcare-Associated Infection (HAI). In recent years isolates producing New Delhi Metallo-β-lactamase (NDM) other β-lactamases have been reported that reduce the efficiency of clinical antimicrobial treatments. this study, we analyzed antibiotic resistance, presence resistance genes clonal relationship two P. obtained from male patients admitted same hospital in Bogotá - Colombia, 2015.
Providencia rettgeri is an opportunistic bacterial pathogen of clinical significance due to its association with urinary tract infections and multidrug resistance. Here, we report the first complete genome sequence P. The strain RB151 consists a 4.8-Mbp chromosome 108-kbp blaNDM-1-positive plasmid.