Elizabeth C. Ailes

ORCID: 0000-0003-2062-8148
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About
Contact & Profiles
Research Areas
  • Pregnancy and Medication Impact
  • Congenital Heart Disease Studies
  • Maternal Mental Health During Pregnancy and Postpartum
  • Prenatal Substance Exposure Effects
  • Pregnancy and preeclampsia studies
  • Cardiovascular Issues in Pregnancy
  • Reproductive Health and Contraception
  • Viral gastroenteritis research and epidemiology
  • Salmonella and Campylobacter epidemiology
  • Mosquito-borne diseases and control
  • Urinary Tract Infections Management
  • Viral Infections and Vectors
  • Listeria monocytogenes in Food Safety
  • Respiratory viral infections research
  • Global Maternal and Child Health
  • Congenital Anomalies and Fetal Surgery
  • Folate and B Vitamins Research
  • Pediatric Urology and Nephrology Studies
  • Cardiovascular Conditions and Treatments
  • Homelessness and Social Issues
  • Gestational Diabetes Research and Management
  • Food Safety and Hygiene
  • Influenza Virus Research Studies
  • Autopsy Techniques and Outcomes
  • Opioid Use Disorder Treatment

Centers for Disease Control and Prevention
2015-2024

National Center on Birth Defects and Developmental Disabilities
2015-2024

October 6 University
2023

The Centers
2012-2023

American Society of Safety Professionals
2023

Center for Surveillance, Epidemiology, and Laboratory Services
2013-2020

Weatherford College
2018

University of Regina
2018

Kimberly-Clark (Canada)
2018

Truven Health Analytics (United States)
2018

Pregnant women living in or traveling to areas with local mosquito-borne Zika virus transmission are at risk for infection, which can lead severe fetal and infant brain abnormalities microcephaly (1). In February 2016, CDC recommended 1) routine testing infection of asymptomatic pregnant ongoing the first prenatal care visit, 2) retesting during second trimester who initially test negative, 3) signs symptoms consistent disease (e.g., fever, rash, arthralgia, conjunctivitis) any time...

10.15585/mmwr.mm6623e1 article EN MMWR Morbidity and Mortality Weekly Report 2017-06-08

Campylobacter is a common but decreasing cause of foodborne infections in the USA. Outbreaks are uncommon and have historically differed from sporadic cases seasonality contamination source. We reviewed reported outbreaks campylobacteriosis. From 1997 to 2008, 262 were reported, with 9135 illnesses, 159 hospitalizations, three deaths. The annual mean was 16 for 1997-2002, 28 2003-2008. Almost half occurred warmer months. Foodborne transmission 225 (86%) outbreaks, water 24 (9%), animal...

10.1017/s0950268812001744 article EN Epidemiology and Infection 2012-08-15

In 2011, critical congenital heart disease was added to the US Recommended Uniform Screening Panel for newborns, but whether state implementation of screening policies has been associated with infant death rates is unknown.To assess there an association between newborn and rates.Observational study group-level analyses. A difference-in-differences analysis conducted using National Center Health Statistics' period linked birth/infant data set files 2007-2013 26 546 503 births through June 30,...

10.1001/jama.2017.17627 article EN JAMA 2017-12-05

Critical congenital heart disease (CCHD) was added to the Recommended Uniform Screening Panel for Newborns in United States 2011. Many states have recently adopted or are considering requirements universal CCHD screening through pulse oximetry birth hospitals. Limited previous research is directly applicable question of how many US infants with might be identified screening.To estimate proportion late detection (>3 days after birth) based on existing clinical practice and investigate factors...

10.1001/jamapediatrics.2013.4779 article EN JAMA Pediatrics 2014-02-03

Disease outbreaks associated with drinking water drawn from untreated groundwater sources represent a substantial proportion (30.3%) of the 818 reported to CDC's Waterborne and Outbreak Surveillance System (WBDOSS) during 1971 2008. The objectives this study were identify underlying contributing factors, suggest improvements for data collection outbreaks, inform outbreak prevention efforts. Two researchers independently reviewed all qualifying reports (1971 2008), assigned factors abstracted...

10.1111/gwat.12121 article EN Ground Water 2013-10-03

In the United States, major structural or genetic birth defects affect approximately 3% of live births (1) and are responsible for 20% infant deaths (2). Birth can persons across their lifespan cause significant lifelong disabilities. CDC used Healthcare Cost Utilization Project (HCUP) 2013 National Inpatient Sample (NIS), a stratified sample discharges from nonfederal community hospitals, to estimate annual cost defect-associated hospitalizations in both all ages by age group. had...

10.15585/mmwr.mm6602a1 article EN MMWR Morbidity and Mortality Weekly Report 2017-01-19

In Colombia, approximately 105,000 suspected cases of Zika virus disease (diagnosed based on clinical symptoms, regardless laboratory confirmation) were reported during August 9, 2015-November 12, 2016, including nearly 20,000 in pregnant women (1,2). infection pregnancy is a known cause microcephaly and serious congenital brain abnormalities has been associated with other birth defects related to central nervous system damage (3). Colombia's Instituto Nacional de Salud (INS) maintains...

10.15585/mmwr.mm6549e1 article EN MMWR Morbidity and Mortality Weekly Report 2016-12-09

In 2011, the US Secretary of Health and Human Services recommended universal screening newborns for critical congenital heart defects (CCHDs), yet few estimates number infants with CCHDs likely to be detected through exist. Our objective was estimate nonsyndromic in United States (true positives) missed (false negatives) newborn CCHD screening.We developed a simulation model based on birth prevalence, prenatal diagnosis, late detection, sensitivity pulse oximetry true-positive false-negative...

10.1542/peds.2014-3662 article EN PEDIATRICS 2015-05-12

CDC has updated its interim guidance for U.S. health care providers caring pregnant women with possible Zika virus exposure, to include the emerging data indicating that RNA can be detected prolonged periods in some women. To increase proportion of infection who receive a definitive diagnosis, recommends expanding real-time reverse transcription-polymerase chain reaction (rRT-PCR) testing. Possible exposures travel or residence an area active transmission, sex* partner traveled resides...

10.15585/mmwr.mm6529e1 article EN MMWR Morbidity and Mortality Weekly Report 2016-07-25

Background: Urinary tract infection (UTI) is the most common bacterial in pregnancy. Known risk factors for UTI pregnancy include diabetes and certain urologic conditions. Other maternal characteristics might also be associated with could provide clues to etiology of Our objective was identify Materials Methods: We used data from pregnant women participating National Birth Defects Prevention Study, a population-based study major structural birth defects 10 U.S. sites, 1997 2011. In...

10.1089/jwh.2020.8946 article EN Journal of Women s Health 2021-09-07

Background. Little is known about the occurrence of Q fever among veterinarians in United States. In this study, we sought to estimate prevalence Coxiella burnetii antibodies and identify risk factors for exposure.

10.1086/596705 article EN Clinical Infectious Diseases 2009-01-23

Health insurance claims are a rich data source to examine medication use in pregnancy. Our objective was identify pregnant women, their pregnancy outcomes, and date of last menstrual period (LMP), estimate antidepressant dispensations pregnancy.From literature search, we identified diagnosis procedure codes indicating the end Using Truven MarketScan® Commercial Claims Encounters Databases, all inpatient admissions outpatient service with these codes. We developed an algorithm assign: (1)...

10.1002/bdra.23573 article EN Birth Defects Research 2016-11-01

Previous studies noted associations between birth defects and some antibiotics (e.g., nitrofurantoin, sulfonamides) but not others penicillins). It is unclear if previous findings were due to antibiotic use, infections, or chance. To control for potential confounding by indication, we examined use defects, among women reporting urinary tract infections (UTIs).The National Birth Defects Prevention Study a multi-site, population-based case-control study. Case infants/fetuses have any of over...

10.1002/bdra.23570 article EN Birth Defects Research 2016-11-01

From 2004 to 2014, the incidence of neonatal abstinence syndrome (NAS) in United States increased 433%, from 1.5 8.0 per 1,000 hospital births. The latest national data 2014 indicate that one baby was born with signs NAS every 15 minutes (1). is a drug withdrawal most commonly occurs among infants after utero exposure opioids, although other substances have also been associated NAS. Prenatal opioid has poor fetal growth, preterm birth, stillbirth, and possible specific birth defects (2-5)....

10.15585/mmwr.mm6801a2 article EN MMWR Morbidity and Mortality Weekly Report 2019-01-10

ABSTRACT Objectives Congenital heart defects (CHDs) occur in nearly 1% of live births. We sought to assess factors associated with prenatal CHD diagnosis the National Birth Defects Prevention Study (NBDPS). Methods analyzed data from mothers CHD‐affected pregnancies 1998 2005. Prenatal was defined as affirmative responses questions about abnormal ultrasounds and fetal echocardiography obtained during a structured telephone interview. Results Fifteen percent (1097/7299) women (excluding...

10.1002/pd.4282 article EN Prenatal Diagnosis 2013-11-13

Background When making decisions about medication use in pregnancy, women consult many information sources, including the Internet. The aim of this study was to assess content publicly accessible YouTube videos that discuss pregnancy. Methods Using 2023 distinct combinations search terms related medications and we extracted metadata from using a video Application Programming Interface. Relevant were defined as those with term pregnancy-related either title or description. We viewed relevant...

10.1002/pds.3911 article EN Pharmacoepidemiology and Drug Safety 2015-11-05

Birth defects are a leading cause of infant mortality in the United States, accounting for 20.6% deaths 2017 (1). Rates attributable to birth (IMBD) have generally declined since 1970s (1-3). U.S. linked birth/infant death data from 2003-2017 were used assess trends IMBD. Overall, rates 10% during 2003-2017, but decreases varied by maternal and characteristics. During IMBD decreased 4% infants Hispanic mothers, 11% non-Hispanic black (black) 12% white (white) mothers. In 2017, these highest...

10.15585/mmwr.mm6902a1 article EN MMWR Morbidity and Mortality Weekly Report 2020-01-16

Pregnancy is a condition of broad interest across many medical and health services research domains, but one not easily identified in healthcare claims data. Our objective was to establish an algorithm identify pregnant women their pregnancies We pregnancy-related diagnosis, procedure, diagnosis-related group codes, accounting for the transition International Statistical Classification Diseases, 10th Revision, Clinical Modification (ICD-10-CM) diagnosis procedure encounter reporting on...

10.1371/journal.pone.0284893 article EN public-domain PLoS ONE 2023-04-24
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