A5103178087- Ovarian function and disorders
- HIV/AIDS Research and Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- HIV, Drug Use, Sexual Risk
- Reproductive Biology and Fertility
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Neuroscience and Neuropharmacology Research
- Estrogen and related hormone effects
- Reproductive System and Pregnancy
- Menopause: Health Impacts and Treatments
- Endometriosis Research and Treatment
- Bone health and osteoporosis research
- Receptor Mechanisms and Signaling
- Sex work and related issues
- Ion channel regulation and function
- Reproductive Health and Technologies
- Health and Wellbeing Research
- Sperm and Testicular Function
- Vitamin D Research Studies
- Gynecological conditions and treatments
- Nutrition and Health in Aging
- Nicotinic Acetylcholine Receptors Study
- Endometrial and Cervical Cancer Treatments
- Public Health Policies and Education
Center for Global Health
2016-2024
Centers for Disease Control and Prevention
2016-2023
Houston Fertility Institute
2013-2022
Office of Readiness and Response
2017
Canterbury District Health Board
2017
Madison Group (United States)
2014
The University of Texas Health Science Center at Houston
2013
Institute for Reproductive Health
2009-2010
University of Cincinnati
2005-2010
California Institute For Rural Studies
2010
Pregnant women living in or traveling to areas with local mosquito-borne Zika virus transmission are at risk for infection, which can lead severe fetal and infant brain abnormalities microcephaly (1). In February 2016, CDC recommended 1) routine testing infection of asymptomatic pregnant ongoing the first prenatal care visit, 2) retesting during second trimester who initially test negative, 3) signs symptoms consistent disease (e.g., fever, rash, arthralgia, conjunctivitis) any time...
Care coordination is an important component of the enhanced prenatal care services provided under recent expansions Medicaid program. The effect maternity on birth outcomes in North Carolina was assessed by comparing women who did and not receive these services.Health program data files, including claims paid for coordination, were linked to 1988 1989 live certificates. Simple comparisons percentages rates supplemented a logistic regression analysis.Among services, low weight rate 21%...
Abstract Background Hispanic immigrant workers dominate California's hired farm workforce. Little is known about their health status; even less those lacking employment authorization. Methods The California Agricultural Workers Health Survey (CAWHS) was a statewide cross‐sectional household survey conducted in 1999. Six hundred fifty‐four completed in‐person interviews, comprehensive physical examinations, and personal risk behavior interviews. Results CAWHS PE Sample comprised mostly of...
In 2016, an estimated 1.5 million females aged 15-24 years were living with human immunodeficiency virus (HIV) infection in Eastern and Southern Africa, where the prevalence of HIV among adolescent girls young women (3.4%) is more than double that for males same age range (1.6%) (1). Progress was assessed toward Joint United Nations Programme on HIV/AIDS (UNAIDS) 2020 targets sub-Saharan Africa (90% those aware their status, 90% HIV-infected persons status antiretroviral treatment [ART],...
Homologous desensitization of D<sub>1</sub> dopamine receptors is thought to occur through their phosphorylation leading arrestin association which interdicts G protein coupling. In order identify the relevant domains receptor phosphorylation, and determine how this leads association, we created a series mutated constructs. one mutant, all serine/threonine residues within 3rd cytoplasmic domain were altered (3rdTOT). A second construct was in only three these serines (serines 256, 258, 259)...
The global target for 2020 is that ≥90% of people living with HIV (PLHIV) receiving antiretroviral therapy (ART) will achieve viral load suppression (VLS). We examined VLS and its determinants among adults ART at least four months.
<h2>Abstract</h2> <i>γ</i>-Aminobutyric acid type A (GABA<sub>A</sub>) receptors are members of the ligand-gated ion channel gene superfamily. Using substituted cysteine accessibility method, we investigated whether residues in <i>α</i><sub>1</sub>M3 membrane-spanning segment water-accessible. Cysteine was substituted, one at a time, for each M3 residue from <i>α</i><sub>1</sub>Ala<sup>291</sup> to <i>α</i><sub>1</sub>Val<sup>307</sup>. The ability these mutants react with water-soluble,...
INCIDENCE OF OS-teoporotic fractures is in women older than 75 years, who constitute a rapidly expanding segment of the US population.Bone mineral density (BMD), which strong risk factor for osteoporosis, continues to decline with age.Indeed, recent prospective studies indicate that bone loss not only from middle age into old but may fact accelerate elderly persons. 1 Given progressive increase physical frailty typically occurs women, an osteoporotic fracture, particularly hip, often...
OBJECTIVES: To determine whether exercise training added to ongoing hormone replacement therapy (HRT) increases bone mineral density (BMD) in physically frail elderly women. DESIGN: Prospective controlled trial. SETTING: University‐based research center. PARTICIPANTS: Twenty‐eight women on HRT, aged 75 and older with physical frailty. INTERVENTIONS: Participants were assigned 9 months of supervised (EXER) or home (HOME) exercise. The EXER program started gradually incorporated resistance...
HIV-1 incidence calculation currently includes recency classification by assay and unsuppressed viral load (VL ≥ 1000 copies/mL) in a recent infection testing algorithm (RITA). However, persons with not virally suppressed taking antiretroviral (ARV) medication may be misclassified.We used data from 13 African household surveys to describe the impact of an ARV-adjusted RITA on estimates.HIV-seropositive samples were tested for using Limiting Antigen (LAg)-Avidity enzyme immunoassay, load,...
Thyroid hormones, which are known to act by genomic mechanisms in peripheral tissues, were found influence the binding and function of GABAA receptor complex brain membranes. Submicromolar concentrations triiodothyronine thyroxine stereospecifically stimulated [35S]t-butylbicyclophosphorothionate (a convulsant ligand for complex) highly washed rat membranes, while higher hormones inhibited radioligand binding. GABA-stimulated36Cl− flux isolated membrane sacs was byl-triiodothyronine with a...
Background We examined the epidemiology and transmission potential of HIV population viral load (VL) in 12 sub-Saharan African countries. Methods analyzed data from Population-based Impact Assessments (PHIAs), large national household-based surveys conducted between 2015 2019 Cameroon, Cote d’Ivoire, Eswatini, Kenya, Lesotho, Malawi, Namibia, Rwanda, Tanzania, Uganda, Zambia, Zimbabwe. Blood-based biomarkers included serology, recency infection, VL. estimated number people living with...
Benzodiazepine binding to γ-aminobutyric acid type A (GABA<sub>A</sub>) receptors allosterically modulates GABA and increases the currents induced by submaximal concentrations. Benzodiazepines induce conformational changes in GABA-binding site extracellular domain, but it is uncertain whether these extend into membrane-spanning domain where channel gate located. Alone, benzodiazepines do not open channel. We used substituted-cysteine-accessibility method investigate diazepam-induced region...
Eighty falloposcopies were performed in fallopian tubes of women with suspected tubal disease. In three (4%), isthmic plugs observed occluding the entire lumen. all cases these mobilized by falloposcopic-directed, selected cannulation and aquadissection techniques. Restoration patency, verified concurrent chromopertubation under laparoscopic monitoring was achieved cases. On one occasion, plug identified on fimbria, patency confirmed. When this retrieved examined histologically, it found to...
To improve early enrollment in HIV care, the Swaziland Ministry of Health implemented new linkage procedures for persons diagnosed during Soka Uncobe male circumcision campaign (SOKA, 2011–2012) and Incidence Measurement Survey (SHIMS, 2011). Abstraction clinical records telephone interviews a retrospective cohort HIV-diagnosed SOKA SHIMS clients were conducted 2013–2014 to evaluate compliance with care at 92 facilities throughout Swaziland. Of 1,105 evaluated, within 3, 12, 24 months...
Identifying men living with HIV in sub-Saharan Africa (SSA) is critical to end the epidemic. We describe underlying factors of unawareness among aged 15-59 years who ever tested for 13 SSA countries.
HIV testing is a critical step to accessing antiretroviral therapy (ART) because early diagnosis can facilitate earlier initiation of ART. This study presents aggregated data individuals who self-reported being HIV-positive but subsequently tested HIV-negative during nationally representative Population-Based Impact Assessment surveys conducted in 11 countries from 2015 2018.
A previous study comparing the performance of different platforms for DNA microarray found that oligonucleotide (oligo) platform containing 385K isothermal probes had best when evaluating dosage sensitivity, precision, specificity, sensitivity and copy number variations border definition. Although oligo has been used in some research fields clinics, it not aneuploidy screening human embryos. The present was designed to use this new preimplantation genetic human. total 383 blastocysts from 72...
Objectives The main objectives of the study are to estimate HIV prevalence, active syphilis and correlates co-infection with in Zambia, among recently sexually individuals aged 15 59 years old. Methods We used data from 2016 Zambia Population-based Impact Assessment (ZAMPHIA), a national household survey that included biomarker testing for syphilis. Chembio DPP® Syphilis Screen Confirm Assay was distinguish between older infections. This is first time has been survey. Log-binominal modelling...