Rebecca J. Free

ORCID: 0000-0001-8605-0532
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About
Contact & Profiles
Research Areas
  • Mosquito-borne diseases and control
  • COVID-19 Impact on Reproduction
  • Antifungal resistance and susceptibility
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Legionella and Acanthamoeba research
  • Global Maternal and Child Health
  • Fungal Infections and Studies
  • Bacterial biofilms and quorum sensing
  • Orthopedic Infections and Treatments
  • Hepatitis C virus research
  • Kawasaki Disease and Coronary Complications
  • Hepatitis B Virus Studies
  • COVID-19 Clinical Research Studies
  • Blood donation and transfusion practices
  • Blood transfusion and management
  • Vibrio bacteria research studies
  • Viral Infections and Vectors
  • Infectious Diseases and Tuberculosis
  • Historical Art and Culture Studies
  • Hemoglobinopathies and Related Disorders
  • Diverse Educational Innovations Studies
  • COVID-19 and healthcare impacts
  • SARS-CoV-2 detection and testing
  • Parasitic Infections and Diagnostics

Centers for Disease Control and Prevention
2022-2025

National Center for Immunization and Respiratory Diseases
2024

National Center for Emerging and Zoonotic Infectious Diseases
2022-2023

Waterborne Environmental (United States)
2023

Pregnant women living in or traveling to areas with local mosquito-borne Zika virus transmission are at risk for infection, which can lead severe fetal and infant brain abnormalities microcephaly (1). In February 2016, CDC recommended 1) routine testing infection of asymptomatic pregnant ongoing the first prenatal care visit, 2) retesting during second trimester who initially test negative, 3) signs symptoms consistent disease (e.g., fever, rash, arthralgia, conjunctivitis) any time...

10.15585/mmwr.mm6623e1 article EN MMWR Morbidity and Mortality Weekly Report 2017-06-08

Abstract Background National Blood Collection and Utilization Surveys (NBCUS) have reported decreases in U.S. blood collections transfusions since 2008. The declines began to stabilize 2015–2017, with a subsequent increase 2019. Data from the 2021 NBCUS were analyzed understand current dynamics of collection use United States. Methods In March 2022, all community‐based (53) hospital‐based (83) centers, randomly selected 40% transfusing hospitals performing 100–999 annual inpatient surgeries,...

10.1111/trf.17360 article EN Transfusion 2023-04-18

Two doses of JYNNEOS vaccine are effective in preventing many mpox cases and can reduce the severity symptoms infected persons.However, infections among fully vaccinated persons occur.During May 2022-May 2024, a total 271 were reported to CDC from 27 U.S. jurisdictions.These estimated have occurred <1% persons.Compared with unvaccinated persons, more likely occur non-Hispanic White men aged 30-39 years, associated increased numbers sexual partners, resulted less severe disease...

10.15585/mmwr.mm7320a3 article EN MMWR Morbidity and Mortality Weekly Report 2024-05-23

BackgroundIn 2021, four patients who had received solid organ transplants in the USA developed encephalitis beginning 2–6 weeks after transplantation from a common donor. We describe an investigation into cause of these patients.MethodsFrom Nov 7, to Feb 24, 2022, we conducted public health involving 15 agencies and medical centres USA. tested various specimens (blood, cerebrospinal fluid, intraocular serum, tissues) donor recipients by serology, RT-PCR, immunohistochemistry, metagenomic...

10.1016/s2666-5247(23)00170-2 article EN cc-by-nc-nd The Lancet Microbe 2023-08-03

Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious condition typically occurring 2-6 weeks after SARS-CoV-2 infection and characterized by fever multiorgan involvement (1,2).In May 2020, CDC created an MIS-C case definition established passive national surveillance system for voluntary reporting state local health departments.*In 2022, the Council of State Territorial Epidemiologists (CSTE) new that went into effect on January 1, 2023 † (3).Approximately 87% cases...

10.15585/mmwr.mm7310a2 article EN MMWR Morbidity and Mortality Weekly Report 2024-03-14

Abstract Coccidioidomycosis, histoplasmosis, and blastomycosis are underrecognized frequently misdiagnosed fungal infections that can clinically resemble bacterial viral community-acquired pneumonia. This guidance is intended to help outpatient clinicians test for these diseases in patients with pneumonia reduce misdiagnoses, unnecessary antibacterial use, poor outcomes.

10.1093/cid/ciad619 article EN public-domain Clinical Infectious Diseases 2023-10-05

Abstract Background SARS-CoV-2 infection can result in serious illness children. We used COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) data to assess characteristics associated with pediatric COVID-19 hospitalizations, including underlying medical conditions and vaccination status. Percent of Hospitalizations† Specific Underlying Medical Conditions among U.S. Children Aged ≤17 Years by Age Group — COVID-NET, January–December 2023 Methods children aged ≤ 17 years as the...

10.1093/ofid/ofae631.141 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Abstract Background Although multisystem inflammatory syndrome in children (MIS-C) incidence has decreased, cases continue to occur and can have notable morbidity mortality. This investigation evaluates clinical demographic risk factors for death from MIS-C.Table 1.Demographic with Multisystem Inflammatory Syndrome Children, United States, 2020-2022 Methods We evaluated reported CDC national MIS-C surveillance illness onset February 2020–December 2022 known outcome. performed multivariable...

10.1093/ofid/ofae631.2161 article EN cc-by Open Forum Infectious Diseases 2025-01-29
Sarah Reagan-Steiner Regina M. Simeone Elizabeth L. Simon Julu Bhatnagar Titilope Oduyebo and 95 more Rebecca J. Free Amy M. Denison D. Brett Rabeneck Sascha Ellington Emily E. Petersen Joy Gary Gillian Hale M. Kelly Keating Roosecelis B. Martines Atis Muehlenbachs Jana M. Ritter Ellen Lee Alexander Davidson Erin E. Conners Sarah Scotland Kayleigh Sandhu Andrea Bingham Elizabeth Kassens Lou C. Smith Kirsten St. George Nina Ahmad Mary R. Tanner Suzanne F. Beavers Brooke Miers Kelley VanMaldeghem Sumaiya Khan Ingrid B. Rabe Carolyn Gould Dana Meaney‐Delman Margaret A. Honein Wun‐Ju Shieh Denise J. Jamieson Marc Fischer Sherif R. Zaki Melissa Kretschmer Kara Tarter Hayley D. Yaglom Shoruq Alhajmohammad Dildeep Chhabra Wendy Jilek Meghana Madala Sharon Messenger Charsey Cole Porse María Salas Diana Singh Sarah Skallet Similoluwa Sowunmi Natalie S. Marzec K. Justin Davis Andrea Morrison M. Zachariah Fraser Colleen Ann O'Connor Wendy M. Chung Folasuyi Richardson Meredith E. Stocks Amanda Marie Bundek Jennifer L. Zambri A. Mark Allen Marie Ketty Etienne Jennifer Jackson Vanessa Landis Teresa C. Logue Nicole Muse Juliana Prieto Mercedes Rojas Amanda Feldpausch Teri Graham Sylvia Mann Sarah Y. Park Debbie Freeman Emily Potts Taryn Stevens Sean Simonson Julius Tonzel Shari Davis Sara Robinson Judie Hyun Erin Jenkins Catherine Brown Susan Soliva Elizabeth Schiffman Paul Byers Sheryl Hand Christine L. Mulgrew Jeff Hamik Samir Koirala Elizabeth Ludwig Carolyn Fredette Abigail Mathewson Kristin Garafalo K. J. Worthington Abubakar Ropri Danielle Bloch Sandhya Clark Hannah Cooper

Zika virus infection during pregnancy can cause congenital microcephaly and brain abnormalities (1), detection of RNA in clinical tissue specimens provide definitive laboratory evidence recent infection. Whereas duration viremia is typically short, prolonged placental, fetal, neonatal has been reported key diagnostic information by confirming (2). In accordance with guidance (3,4), CDC provides testing placental fetal tissues situations where this could add value. This report describes the...

10.15585/mmwr.mm6624a3 article EN MMWR Morbidity and Mortality Weekly Report 2017-06-22

Reports have suggested the COVID-19 pandemic resulted in blood donation shortages and adverse impacts on supply. Using data from National Blood Collection Utilization Survey (NBCUS), we quantified pandemic's impact red cell (RBC) apheresis platelet collections transfusions United States during year 2020.The 2021 NBCUS survey instrument was modified to include certain collection utilization variables for 2020. The distributed all US centers, hospitals performing ≥1000 surgeries annually, a...

10.1111/trf.17359 article EN Transfusion 2023-04-13

Abstract Drowned organ donors can be exposed to environmental molds through the aspiration of water; transplantation organs cause invasive mold infections in recipients. We describe 4 rapidly fatal cases potentially donor-derived United States, highlighting importance maintaining clinical suspicion for these transplant

10.3201/eid2907.230524 article EN cc-by Emerging infectious diseases 2023-06-15

Abstract Background The Department of Health and Human Services' National Blood Collection Utilization Survey (NBCUS) has been conducted biennially since 1997. Data are used to estimate national blood collection use. Supplemental data from the 2021 NBCUS not presented elsewhere here. Methods on survey participation, donor characteristics, component cost, transfusion‐associated adverse reactions, implementation safety measures, including pathogen‐reduction platelets, during 2021, were...

10.1111/trf.17509 article EN Transfusion 2023-09-13

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmissible through lung transplantation, and outcomes among infected organ recipients may be severe. Transmission risk to extrapulmonary recent (within 30 days of transplantation) SARS-CoV-2-infected recipient are unclear.During March 2020-March 2021, potential SARS-CoV-2 transmissions solid transplantation were investigated. Assessments included testing, medical record review, determination likely transmission route,...

10.1093/ofid/ofac221 article EN cc-by-nc-nd Open Forum Infectious Diseases 2022-05-02

In July 2022, the Pennsylvania Department of Health received two reports laboratory-confirmed Legionnaires disease in patients who had recently lung transplants from same donor at a single hospital. The donor's cause death was freshwater drowning river, raising suspicion potential donor-derived transmission, because Legionella bacteria naturally live fresh water. Further investigation receiving other organs did not identify additional legionellosis cases. care-associated infection caused by...

10.15585/mmwr.mm7237a1 article EN MMWR Morbidity and Mortality Weekly Report 2023-09-14

The U.S. Public Health Service (PHS) has periodically published recommendations about reducing the risk for transmission of HIV, hepatitis B virus (HBV), and C (HCV) through solid organ transplantation (1-4). Updated guidance in 2020 included recommendation that all transplant candidates receive HBV, HCV testing during hospital admission surgery to more accurately assess their pretransplant infection status better identify donor transmitted (4). In 2021, CDC was notified this might be...

10.15585/mmwr.mm7126a2 article EN MMWR Morbidity and Mortality Weekly Report 2022-06-30

A central challenge in short-term study abroad programs is making sure that students have meaningful interactions with people abroad, something scholarship has shown to be tremendously beneficial, both for linguistic gains and cross-cultural exchange. This article examines the potential benefits of collaborative mapping encouraging student interaction local residents, while also considering value spatial analysis interdisciplinary aims a course centered on theatre French Studies. One author...

10.3366/ijhac.2018.0202 article EN International Journal of Humanities and Arts Computing 2018-03-01

In October 2017, the Nebraska Department of Health and Human Services (NDHHS) was notified by a local health department gastrointestinal illness outbreak among attendees wedding reception at facility A, an event center. Shortly thereafter, state public officials began receiving reports similar subsequent A events. An investigation initiated to identify cases, establish cause, assess possible transmission routes, provide control recommendations. Overall, 159 cases consistent with norovirus...

10.15585/mmwr.mm6828a2 article EN MMWR Morbidity and Mortality Weekly Report 2019-07-18
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