A5016938435- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Global Maternal and Child Health
- Hepatitis B Virus Studies
- HIV/AIDS drug development and treatment
- Sex work and related issues
- Data-Driven Disease Surveillance
- Hepatitis C virus research
- Viral Infections and Outbreaks Research
- Genital Health and Disease
- Mosquito-borne diseases and control
- Malaria Research and Control
- COVID-19 epidemiological studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Viral Infections and Vectors
- Mobile Health and mHealth Applications
- HIV/AIDS Impact and Responses
- Female Genital Mutilation/Cutting Issues
- Liver Disease Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Ethics in Clinical Research
- ICT in Developing Communities
- Diagnosis and treatment of tuberculosis
Rwanda Biomedical Center
2016-2025
Ministry of Health
2015-2025
John H. Stroger, Jr. Hospital of Cook County
2024
University of Rwanda
2016-2023
University of Basel
2021-2022
Swiss Tropical and Public Health Institute
2021-2022
Instituut voor Tropische Geneeskunde
2021
University Hospital of Basel
2021
University of Global Health Equity
2021
University of West Florida
2018
BackgroundRwanda has achieved substantial progress in scaling up of antiretroviral therapy. We aimed to assess the effect increased access therapy on life expectancy among HIV-positive patients two distinct periods lower and higher coverage (1997–2007 2008–11).MethodsIn a retrospective observational cohort study, we collected clinical demographic data for all enrolled care at 110 health facilities across five provinces Rwanda. included aged 15 years or older with known enrolment date between...
Hepatitis C virus (HCV) infection is a pandemic causing disease; more than 185 million people are infected worldwide. An HCV antibody (Ab) prevalence of 6.0% was estimated in Central African countries. The study aimed at providing estimates among pregnant women Rwanda. surveillance through screening test attending antenatal clinics performed 30 HIV sentinel sites Among 12,903 tested clinics, 335 (2.6% [95% Confidence Interval 2.32–2.87]) positive for Ab. Ab aged 25–49 years 2.8% compared to...
The 2018-2019 Rwanda Population-based HIV Impact Assessment (RPHIA) was conducted to measure national incidence and prevalence. District-level estimates were modeled inform resources allocation.RPHIA a nationally representative cross-sectional household survey. Consenting adults interviewed tested for using the diagnostic algorithm followed by laboratory-based confirmation of status testing viral load (VL), limiting antigen (LAg) avidity, presence antiretrovirals. Incidence calculated...
A Rift Valley fever epizootic affected livestock in Rwanda during March-October 2022. We confirmed 3,112 infections with the virus, including 1,342 cases, 1,254 abortions, and 516 deaths among cattle, goats, sheep. recommend a One Health strategy for investigations response to protect animal human health.
Community isolation of patients with communicable infectious diseases limits spread pathogens but our understanding isolated patients’ needs and challenges is incomplete. Rwanda deployed a digital health service nationally to assist public clinicians remotely monitor support SARS-CoV-2 cases via their mobile phones using daily interactive short message (SMS) check-ins. We aimed assess the texting patterns communicated topics better understand patient experiences. extracted data on all...
Cardiovascular diseases (CVDs) pose a significant health challenge worldwide, particularly in low-and middle-income countries, including Rwanda. A National Cardiothoracic Surgery Symposium was held on February 23, 2024, Kigali, Bringing together key stakeholders and experts the field, focused establishment of sustainable cardiothoracic surgery program The discussed current surgical outcomes, sustainability, early diagnosis follow-up strategies, development cardiovascular disease research...
<title>Abstract</title> Background: Despite national efforts, cervical cancer screening participation remains critically low in Rwanda. This study assesses the prevalence, barriers, and socio-economic determinants of among Rwandan women. Methods: cross-sectional utilized data from 2022 Rwanda Non-Communicable Diseases Risk Factors STEPS Survey. Data a sample 2,719 women aged 30-69 years were analyzed using descriptive statistics Poisson regression to identify predictors not undergoing...
Abstract Background Malaria remains a significant health issue in Rwanda. Primary malaria prevention methods include insecticide-treated nets and indoor residual spraying as core interventions. Mosquito repellents, larval source management (LSM), housing improvement are recommended supplemental vector control methods. A 2020–2021 study rice field habitats of peri-urban Kigali City successfully evaluated the entomological epidemiological impacts drone-based larviciding using Bacillus...
Introduction: Rwanda has initiated recency testing alongside existing HIV services (HTS) of provider-initiated testing, partner notification and prevention mother-to-child transmission. We aimed to determine characteristics the newly diagnosed population using a nationwide cohort. Methods: included all patients aged 15 above who consented assessed patient health center related predictors recent infection multivariable logistic regression models. Results: obtained data from 485 565 facilities...
Marburg Virus Disease (MVD) poses a significant global health risk due to its high case fatality rates (24%-88%) and the diagnostic challenges posed by non-specific early symptoms, which overlap with other febrile illnesses like malaria. This study analyzed symptom patterns from 2024 MVD outbreak in Rwanda refine definitions enhance detection. A retrospective analysis was conducted of 6,613 suspected cases (66 positive, 6,547 negative) reported between September 27 December 20, 2024. Symptom...
Background. The prevalence of syphilis among HIV-infected people is a public health concern, but there limited literature to describe the true burden in resource-limited settings. We conducted this survey 2013 estimate syphilis. Methods. A cross-sectional survey. Participants were tested for and HIV. Factors associated with infection identified. Results. was 0.9% (95% CI: 0.7-1.1). This higher 25-49-year-old age (1.1% [95% 0.8-1.3]) than 15-24-year-old (0.6% 0.4-0.9)). Women lower education...
Hepatitis B virus (HBV) affects people worldwide but the local burden especially in pregnant women and their new born babies is unknown. In Rwanda HIV-infected individuals who are also infected with HBV supposed to be initiated on ART immediately. easily transmitted from mother child during delivery. We sought estimate prevalence of chronic infection among attending ante-natal clinic (ANC) determine factors associated HIV co-infection. This study used a cross-sectional survey, targeting...
Background: Couples' voluntary HIV counseling and testing (CVCT) is a WHO-recommended intervention for prevention of heterosexual transmission which very few African couples have received. We report the successful nationwide implementation CVCT in Rwanda. Methods: From 1988 to 1994 Rwanda, pregnant postpartum women were tested requested their husbands. Partner was associated with more condom use lower sexually transmitted infection rates, particularly among HIV-discordant couples. After...
Electronic health records (EHRs) have been implemented in many low-resource settings but lack strong evidence for usability, use, user confidence, scalability, and sustainability. This study aimed to evaluate staff use perceptions of an EHR widely used HIV care >300 facilities Rwanda, providing on factors influencing current performance, A randomized, cross-sectional, structured interview survey center was designed assess functionality, attitudes toward the clinical alerts. associated...
Abstract The ongoing outbreak of Marburg virus disease (MVD) in Rwanda marks the third largest historically, though it has exhibited lowest fatality rate. Genomic analysis identified a lineage with limited internal diversity most closely related to genome sequence from sporadic case sampled 2014 Uganda, lineages have diverged common ancestor that was circulating for decades animal reservoir. Notably, data also provide evidence resulted single zoonotic transmission event human-to-human...
Aiming to reach UNAIDS 90-90-90 targets, nearly all sub-Saharan African countries have expanded antiretroviral therapy (ART) people living with HIV (PLWH) (Treat All). Few published data exist on viral load testing and suppression under Treat All in this region. We assessed proportions of patients available test results who were virally suppressed, as well factors associated suppression, among PLWH 10 Rwandan health centres after implementation.Cross-sectional study during 2018 adults (≥15...
Introduction HIV treatment guidelines recommend that all people living with (PLWH) initiate antiretroviral therapy (ART) as soon possible after diagnosis (Treat All). As Treat All is more widely implemented, an increasing proportion of PLWH are likely to ART when they asymptomatic, and may view the relative benefits risks differently than those initiating at advanced disease stages. To date, patient perspectives care under in sub-Saharan Africa have not been well described. Methods From...
Nearly all countries in sub-Saharan Africa have adopted policies to provide antiretroviral therapy (ART) persons living with HIV (Treat All), though care outcomes of these programmes are not well-described. We estimated changes ART initiation and retention following Treat All implementation Rwanda July 2016.We conducted an interrupted time series analysis adults enrolling at ten Rwandan health centres from 2014 September 2017. Using segmented linear regression, we assessed levels trends...
Introduction COVID-19 has shown an exceptionally high spread rate across and within countries worldwide. Understanding the dynamics of such infectious disease transmission is critical for devising strategies to control its spread. In particular, Rwanda was one African that started preparedness early in January 2020, a total lockdown imposed when country had only 18 confirmed cases known. Using intensive contact tracing, several infections were identified, with majority them being returning...
Identifying men living with HIV in sub-Saharan Africa (SSA) is critical to end the epidemic. We describe underlying factors of unawareness among aged 15-59 years who ever tested for 13 SSA countries.