A5025312154- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Hepatitis B Virus Studies
- Herpesvirus Infections and Treatments
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Viral Infections and Outbreaks Research
- COVID-19 epidemiological studies
- Cytomegalovirus and herpesvirus research
- Quality and Safety in Healthcare
- Bacteriophages and microbial interactions
- Fungal Infections and Studies
- Viral gastroenteritis research and epidemiology
- Meta-analysis and systematic reviews
- Clinical Laboratory Practices and Quality Control
- HIV Research and Treatment
- Computational Drug Discovery Methods
- Machine Learning and Algorithms
- Malaria Research and Control
- HIV-related health complications and treatments
- Mosquito-borne diseases and control
- HIV/AIDS Research and Interventions
- Biosensors and Analytical Detection
- Microbial infections and disease research
Rwanda Biomedical Center
2014-2024
Ministry of Health
2020-2024
Suppressing infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will probably require the rapid identification and isolation individuals infected with virus on an ongoing basis. Reverse-transcription polymerase chain reaction (RT-PCR) tests are accurate but costly, which makes regular testing every individual expensive. These costs a challenge for all countries around world, particularly low-to-middle-income countries. Cost reductions can be achieved by pooling (or...
Abstract The ongoing outbreak of Marburg virus disease (MVD) in Rwanda marks the third largest historically, though it has exhibited lowest fatality rate. Genomic analysis identified a lineage with limited internal diversity most closely related to genome sequence from sporadic case sampled 2014 Uganda, lineages have diverged common ancestor that was circulating for decades animal reservoir. Notably, data also provide evidence resulted single zoonotic transmission event human-to-human...
Suppressing SARS-CoV-2 will likely require the rapid identification and isolation of infected individuals, on an ongoing basis. RT-PCR (reverse transcription polymerase chain reaction) tests are accurate but costly, making regular testing every individual expensive. The costs a challenge for all countries particularly developing countries. Cost reductions can be achieved by pooling (or combining) subsamples them in groups. We propose algorithm based geometry hypercube that, at low...
In 2009, to improve the performance of laboratories and strengthen healthcare systems, World Health Organization Regional Office for Africa (WHO AFRO) partners launched two initiatives: a laboratory quality improvement programme called Strengthening Laboratory Management Toward Accreditation (SLMTA), what is now Stepwise Quality Improvement Process Towards (SLIPTA).This study describes achievements Rwandan four years after introduction SLMTA in country, using SLIPTA scoring system measure...
Artemisinin-based combination therapies (ACTs) have proven highly effective in reducing malaria morbidity sub-Saharan Africa. Artemether–lumefantrine (AL) was introduced 2005 as a first-line ACT for the treatment of uncomplicated Rwanda. Monitoring therapeutic efficacy ACTs is necessary to ensure case management. A comparative study on AL and dihydroartemisinin–piperaquine (DHP) conducted two sites, Masaka Ruhuha, between September 2013 December 2015. Clinical parasitological responses were...
Suppressing SARS-CoV-2 will likely require the rapid identification and isolation of infected individuals, on an ongoing basis. RT-PCR (reverse transcription polymerase chain reaction) tests are accurate but costly, making regular testing every individual expensive. The costs a challenge for all countries particularly developing countries. Cost reductions can be achieved by combining samples them in groups. We propose algorithm grouping subsamples, prior to testing, based geometry hypercube....
Central nervous system (CNS) infection is a common and serious disease that needs rapid appropriate diagnosis for an treatment. However, in most recourse limited setting including Rwanda, conventional microbiological method the only way to establish confirmed infectious etiology. This was 4 years retrospective review of registers electronic laboratory records aimed determine causative agents hospitalized patient’s suspected be suffering from CNS at four referral hospitals Rwanda. In this...
Abstract Background: Cytokines network drive Human Immunodeficiency Virus (HIV) inflammation and pathogenesis. Highly Active Antiretroviral Therapy (HAART) maintains low HIV viral load (VL) but chronic remains high in subjects compared to naïve population. To date, there is no surrogate biomarker that gives the hallmark picture of immune activation, programs. This study aimed at determining plasma cytokine levels their association with VL initiation after six months on HAART Rwanda. Methods:...