- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Genomics and Phylogenetic Studies
- Respiratory viral infections research
- Microbial infections and disease research
- Glutathione Transferases and Polymorphisms
- Herpesvirus Infections and Treatments
- Viral Infections and Vectors
- Marine Biology and Ecology Research
- Genomics, phytochemicals, and oxidative stress
- COVID-19 Clinical Research Studies
- Pharmacogenetics and Drug Metabolism
- Pesticide Exposure and Toxicity
- Identification and Quantification in Food
- Influenza Virus Research Studies
- Environmental Toxicology and Ecotoxicology
- Cancer, Hypoxia, and Metabolism
- Photodynamic Therapy Research Studies
- Pesticide and Herbicide Environmental Studies
- Reproductive biology and impacts on aquatic species
- Microbial Community Ecology and Physiology
- Epigenetics and DNA Methylation
- SARS-CoV-2 detection and testing
- Mass Spectrometry Techniques and Applications
- Marine Biology and Environmental Chemistry
Korea Disease Control and Prevention Agency
2012-2021
Korea Center for Disease Control and Prevention
2008-2020
Korea National Institute of Health
2011-2014
Hanyang University
2005-2009
Dankook University
2003
Korea Institute of Science and Technology
1996
The World Health Organization (WHO) coordinates the Global Invasive Bacterial Vaccine-Preventable Diseases (IB-VPD) Surveillance Network to support vaccine introduction decisions and use. network was established strengthen surveillance laboratory confirmation of meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis.
Mitochondrial DNA was isolated from the Korean freshwater gobioid fish Odontobutis platycephala by long‐polymerase chain reaction with conserved primers and this mtDNA sequenced primer walking using flanking sequences as sequencing primers. The resultant O. sequence found to be 17 588 bp in size a mostly structural organization when compared that of other teleost fish. Rearrangements tRNAs (tRNA‐Ser, tRNA‐Leu, tRNA‐His) an additional non‐coding region (533 bp) were present between ND4 ND5...
Background Limited data on the incidence and clinical characteristics of adult pertussis infections are available in Korea. Methods Thirty-one hospitals Korean Centers for Disease Control Prevention collaborated to investigate among adults with a bothersome cough non-outbreak, ordinary outpatient settings. Nasopharyngeal aspirates or nasopharyngeal swabs were collected polymerase chain reaction (PCR) culture tests. Results The study enrolled 934 patients between September 2009 April 2011....
Pertussis is a representative vaccine-preventable disease. However, there have been recent outbreaks in countries where even higher vaccination against the One reason emergence of antigenic variants, which are different to vaccine type. In Korea, reported cases rapidly increased since 2009. Therefore, we analyzed genotype strains isolated 2011-2012 by multilocus sequence typing method. As expected, profiles tested genes dramatically changed. The major type changed from ST1 ST2, and new (ST8)...
To confirm genotype diversities of clinical isolates Bordetella pertussis and to evaluate the risk outbreak in Korea.Seven housekeeping genes 10 antigenic determinant from B. were analyzed by Multilocus sequence typing (MLST).More variant pattern was observed genes. Especially, PtxS1 gene most gene; five genotypes eight global genotypes. In bacterial type, number types seven frequent form type 1 (79.6%). This major also showed a time-dependent transition pattern. Older (1968 1975) 6 genes,...
The Korea Centers for Disease Control and Prevention has published "A Guideline Unknown Outbreaks (UDO)." aim of this report was to introduce tabletop exercises (TTX) prepare UDO in the future.The Laboratory Analyses Task Force April 2018, assigned unknown diseases into 5 syndromes, designed an algorithm diagnosis, made a panel list diagnosis by exclusion. Using guidelines laboratory analyses UDO, TTX were introduced.Since September 9th, been preparing based on scenario outbreak caused novel...
We cloned two Bombina orientalis ferritin heavy chains (ferritin 1 and 2) one hemoglobin β-chain gene from a B. oviduct cDNA library, the length of transcripts was 882, 858 611 bp encoding 177, 177 148 aa, respectively. chain genes showed high similarity to those amphibia (88–93%), mammals (70–71%), fishes (70–72%), moderate amphibian (65–68%) mammalian (54–57%) genes, Based on phylogenetic analysis, were clustered same clade in amphibia. The different tissue-specific expression patterns....
Tumor hypoxia, either pre-existing or as a result of oxygen bleaching during Photodynamic Therapy (PDT) light irradiation, can significantly reduce the effectiveness PDT induced cell killing. To overcome effect tumor hypoxia and improve killing, we propose using supplemental hyperoxygenation Photofrin PDT. Our previous study has demonstrated that, in an vivo model, control be improved by normobaric hyperbaric 100% supply. The mechanism for cure enhancement hyperoxygenation-PDT combined...
Background: Recently, the pertussis incidences in Korea has been increasing. The average annual incidence of 2000-2008 was 18 cases/year. However, it rapily increased to 66 cases/year at 2009. Moreover, most high 2011, 89 for last 10 years. Therefore, we analyzed genotype variations 7 house keeping genes and antigenic determinant evaluate level changes currently distributing strains. Methods: Total 83 B. strains isolated from 2000 2011 were this study. target genes. After sequencing genes,...