A5079096045- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- Tuberculosis Research and Epidemiology
- Infective Endocarditis Diagnosis and Management
- COVID-19 Pandemic Impacts
- Otolaryngology and Infectious Diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Ocular Infections and Treatments
- Antibiotic Resistance in Bacteria
- Criminal Justice and Corrections Analysis
- Dental Research and COVID-19
- Neonatal and Maternal Infections
- Influenza Virus Research Studies
- Legionella and Acanthamoeba research
- Governance, Compliance, and Sustainability
- Bacterial Identification and Susceptibility Testing
- Ocular Diseases and Behçet’s Syndrome
- Antibiotic Use and Resistance
- Biochemical and Structural Characterization
- Antimicrobial Resistance in Staphylococcus
Ministerio de Salud Pública y Bienestar Social
2016-2024
National Public Health Laboratory
2021
Public Health Laboratory
2021
IPS Central
2021
Instituto Adolfo Lutz
2020
BackgroundThe Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, and agalactiae. We aimed analyse incidence distribution these during first 2 years compared preceding pandemic.MethodsFor this prospective analysis, laboratories in 30 countries territories representing five continents submitted surveillance data from Jan...
Serotype-specific surveillance for invasive pneumococcal disease (IPD) is essential assessing the impact of 10- and 13-valent conjugate vaccines (PCV10/13). The Pneumococcal Serotype Replacement Distribution Estimation (PSERENADE) project aimed to evaluate global evidence estimate PCV10/13 by age, product, schedule, syndrome. Here we systematically characterize summarize landscape routine serotype-specific IPD in PCV10/13-using countries describe subset that are included PSERENADE. Of 138...
Streptococcus pneumoniae is a cause of invasive diseases such as pneumonia, meningitis, and other serious infections among children adults in Paraguay. This study was conducted to establish S . baseline prevalence, serotype distribution, antibiotic resistance patterns healthy aged 2 59 months ≥60 years age prior the introduction PCV10 national childhood immunization program Between April July 2012, total 1444 nasopharyngeal swabs were collected, 718 from 726 age. The pneumococcal isolation,...
Introduction. Colonization by Neisseria meningitidis is the pre-requisite for development of disease. We present findings a cross-sectional investigation onto oropharyngeal carriage N. and species in population aged 3 to 21 Paraguay. Aim. Carriage prevalence age groups, risk factors associated with carriage, phenotypic genotypic characteristics strains are described. Methodology. collected 2011 swabs from consenting participants 3–21 years. Infants were recruited at immunization clinics,...
Background: Widespread use of pneumococcal conjugate vaccines (PCVs) has reduced vaccine-type invasive disease (IPD). We describe the serotype distribution IPD after extensive PCV10 and PCV13 globally.Methods: data were obtained from surveillance sites globally that exclusively used or in their national immunization program had primary series uptake ≥70%. Serotype was estimated for cases occurring ≥5 years post-introduction (i.e., mature PCV10/13 period) using multinomial Dirichlet...
Describe the phenotypical and genotypical characteristics of Neisseria meningitidis isolates from cases meningococcal disease in Paraguay between 1996 2015.Conventional microbiological methods molecular techniques were used to study 114 N. 12 clinical samples without isolation (confirmed by polymerase chain reaction), provided various sentinel centers collaborating Paraguay.The most affected age group was children under 1 year (19.0%), followed 1-5-year-olds (17.5%). The highest percentage...
Streptococcus pneumoniae sigue siendo una de las causas más importantes morbilidad y mortalidad en niños adultos alrededor del mundo. El objetivo estudio fue describir la frecuencia aislamiento S. enfermedad invasiva, distribución serotipos sensibilidad antimicrobiana Paraguay (2010-2018). Se estudiaron 793 cepas aisladas pacientes todas edades con invasiva Paraguay, provenientes los diferentes centros centinelas colaboradores el marco vigilancia meningitis neumonÃas, durante periodo...
La resistencia a los antimicrobianos (RAM) es una grave amenaza global que compromete la eficacia de tratamientos contra infecciones, siendo fundamental su detección temprana y el monitoreo continuo mecanismos emergentes resistencia. El objetivo este trabajo fue evaluar susceptibilidad antimicrobiana bacterias importancia clínica aisladas infecciones nosocomiales ambulatorias en Paraguay durante año 2023. Fueron analizados Sección Antimicrobianos del Dpto. Bacteriología Micología Laboratorio...
Se describe la frecuencia de aislamientos S. pneumoniae causante enfermedad neumocócica invasiva (ENI) en adultos, distribución los serotipos y su sensibilidad antimicrobiana Paraguay durante el periodo 2013-2018.Se trata un estudio descriptivo observacional retrospectivo corte transversal que se estudiaron total 269 cepas aisladas líquido cefalorraquídeo (LCR) (76/269), pleural (174/269) hemocultivo 19/269), provenientes diferentes centros centinelas colaboradores vigilancia meningitis...
Introducción. El serotipo 14 de Streptococcus pneumoniae es una causa importante enfermedades neumocócicas invasivas en todo el mundo. A menudo presenta resistencia a variedad agentes antimicrobianos, lo que genera dificultades tratamiento. Se dispone datos limitados sobre la población pediátrica Paraguay, por monitoreo los serotipos y antimicrobianos causan enfermedad neumocócica. Objetivo: Evaluar las relaciones clonales aislamientos S. invasivo recuperados niños menores cinco años asociar...
Introduction.Streptococcus pneumoniae remains a major cause of mortality and morbidity worldwide in children <5 years age, even with advances vaccination programmes.Hypothesis/Gap Statement. Reviewing reporting trends the distribution pneumococcal serotypes antimicrobial resistance Paraguay will be useful for decision-making public health.Aim. This study analysed serotype S. characteristics disease old before after introduction conjugate vaccines (PCVs).Methodology. A total 885 isolates 278...
Objetivos: Determinar la frecuencia de neumonías bacterianas atípicas causadas por Legionella pneumophila, Mycoplasma pneumoniae y Chlamydophila pneumoniae, en niños adultos Paraguay durante el periodo 2014-2017 técnicas moleculares.
 Materiales métodos: se incluyeron este estudio 148 muestras líquido pleural con diagnóstico neumonía adquirida comunidad (NAC) 2014 a febrero 2017. Las fueron remitidas al Laboratorio Central Salud Pública los Centros Centinelas Colaboradores Red...
La enfermedad meningocócica representa un problema de salud pública y una las principales causas morbilidad mortalidad en todo el mundo. Los serogrupos que causan la mayor carga a nivel global son A, B, C, W e Y. El objetivo del estudio fue describir los resistencia antimicrobiana Neisseria meningitidis aisladas invasiva Paraguay durante periodo 2010-2020. Se estudiaron todas muestras líquido cefalorraquídeo sangre con aislamientos o detección ADN por PCR N. pacientes diversas edades, fueron...